Gingerol and Its Role in Chronic Diseases (Q38988577)

8 September 2017

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title

Gingerol and Its Role in Chronic Diseases (English)

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8 September 2017

Yasmin Anum Mohd Yusof

series ordinal

1

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PubMed ID

27771925

8 September 2017

language of work or name

English

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publication date

1 January 2016

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Advances in Experimental Medicine and Biology

8 September 2017

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8 September 2017

929

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8 September 2017

177-207

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Effect of the combination of gelam honey and ginger on oxidative stress and metabolic profile in streptozotocin-induced diabetic Sprague-Dawley rats

8 September 2017

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Molecular targets of dietary agents for prevention and therapy of cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Ginger prevents Th2-mediated immune responses in a mouse model of airway inflammation

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Anticancer Effect of Ginger Extract against Pancreatic Cancer Cells Mainly through Reactive Oxygen Species-Mediated Autotic Cell Death

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Gingerol metabolite and a synthetic analogue Capsarol inhibit macrophage NF-kappaB-mediated iNOS gene expression and enzyme activity

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Anti-diabetic and hypolipidaemic properties of ginger (Zingiber officinale) in streptozotocin-induced diabetic rats.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Some phytochemical, pharmacological and toxicological properties of ginger (Zingiber officinale Roscoe): a review of recent research

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

The role of the Wnt signalling pathway in colorectal tumorigenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Nuclear factor-kappa B and cancer: its role in prevention and therapy

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Stability of [6]-gingerol and [6]-shogaol in simulated gastric and intestinal fluids

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Effectiveness and safety of ginger in the treatment of pregnancy-induced nausea and vomiting.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Ginger and its health claims: molecular aspects

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Regulation of cell death protease caspase-9 by phosphorylation

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

[6]-Gingerol isolated from ginger attenuates sodium arsenite induced oxidative stress and plays a corrective role in improving insulin signaling in mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Involvement of PI3K/Akt pathway in cell cycle progression, apoptosis, and neoplastic transformation: a target for cancer chemotherapy.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Effects of ginger supplementation on cell-cycle biomarkers in the normal-appearing colonic mucosa of patients at increased risk for colorectal cancer: results from a pilot, randomized, and controlled trial

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

p27KIP1 phosphorylation by PKB/Akt leads to poor breast cancer prognosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Cycling to cancer with cyclin D1

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Pharmacokinetics of [6]-gingerol after intravenous administration in rats.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Blocking of tumor promoter-induced AP-1 activity inhibits induced transformation in JB6 mouse epidermal cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Role of chemopreventive agents in cancer therapy

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Comparative antioxidant and anti-inflammatory effects of [6]-gingerol, [8]-gingerol, [10]-gingerol and [6]-shogaol

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Efficacy of ginger for nausea and vomiting: a systematic review of randomized clinical trials

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Inhibition of human neutrophil 5-lipoxygenase activity by gingerdione, shogaol, capsaicin and related pungent compounds

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

PI3K/Akt signalling pathway and cancer.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Extrinsic versus intrinsic apoptosis pathways in anticancer chemotherapy

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Defining the role of mTOR in cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Enterohepatic recirculation of bioactive ginger phytochemicals is associated with enhanced tumor growth-inhibitory activity of ginger extract.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Ginger extract (Zingiber officinale) has anti-cancer and anti-inflammatory effects on ethionine-induced hepatoma rats

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Isolation of 6-, 8-, and 10-Gingerol from Ginger Rhizome by HPLC and Preliminary Evaluation of Inhibition ofMycobacteriumaviumandMycobacteriumtuberculosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Inhibitory effect of [6]-gingerol on melanogenesis in B16F10 melanoma cells and a possible mechanism of action

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

[8]-Gingerol inhibits melanogenesis in murine melanoma cells through down-regulation of the MAPK and PKA signal pathways

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

6-Shogaol, an active constituent of dietary ginger, induces autophagy by inhibiting the AKT/mTOR pathway in human non-small cell lung cancer A549 cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

[6]-Gingerol inhibits nitric oxide synthesis in activated J774.1 mouse macrophages and prevents peroxynitrite-induced oxidation and nitration reactions

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Ginger ingredients reduce viability of gastric cancer cells via distinct mechanisms

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

31 March 2020

Global cancer statistics

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

[6]-Gingerol suppresses colon cancer growth by targeting leukotriene A4 hydrolase

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Characterization of gingerol-related compounds in ginger rhizome (Zingiber officinale Rosc.) by high-performance liquid chromatography/electrospray ionization mass spectrometry

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Effect of ginger root on cyclooxygenase-1 and 15-hydroxyprostaglandin dehydrogenase expression in colonic mucosa of humans at normal and increased risk for colorectal cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Fresh organically grown ginger (Zingiber officinale): composition and effects on LPS-induced PGE2 production.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Commercially processed dry ginger (Zingiber officinale): composition and effects on LPS-stimulated PGE2 production

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

10-Gingerol inhibits proliferation and invasion of MDA-MB-231 breast cancer cells through suppression of Akt and p38MAPK activity.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

(S)-[6]-Gingerol inhibits TGF-β-stimulated biglycan synthesis but not glycosaminoglycan hyperelongation in human vascular smooth muscle cells.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

[6]-Gingerol, a pungent ingredient of ginger, inhibits angiogenesis in vitro and in vivo

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

[6]-Gingerol prevents UVB-induced ROS production and COX-2 expression in vitro and in vivo

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

[6]-Gingerol Prevents Disassembly of Cell Junctions and Activities of MMPs in Invasive Human Pancreas Cancer Cells through ERK/NF- κ B/Snail Signal Transduction Pathway

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Inhibitory effects of [6]-gingerol on PMA-induced COX-2 expression and activation of NF-kappaB and p38 MAPK in mouse skin

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

[6]-Gingerol inhibits COX-2 expression by blocking the activation of p38 MAP kinase and NF-kappaB in phorbol ester-stimulated mouse skin

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Inhibitors of prostaglandin biosynthesis from ginger

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Gingerols and related analogues inhibit arachidonic acid-induced human platelet serotonin release and aggregation

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

The effect of extracts from ginger rhizome on inflammatory mediator production.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Gingerol sensitizes TRAIL-induced apoptotic cell death of glioblastoma cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Induction of apoptosis in HL-60 cells by pungent vanilloids, [6]-gingerol and [6]-paradol

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

[6]-Gingerol inhibits metastasis of MDA-MB-231 human breast cancer cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Multiple mechanisms are involved in 6-gingerol-induced cell growth arrest and apoptosis in human colorectal cancer cells.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

[6]-Gingerol attenuates β-amyloid-induced oxidative cell death via fortifying cellular antioxidant defense system

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

6-Gingerol Inhibits Growth of Colon Cancer Cell LoVo via Induction of G2/M Arrest

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

An enantioselective synthesis of (+)-(S)-[n]-gingerols via the L-proline-catalyzed aldol reaction

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Inflammation and cancer: role of nuclear factor-kappaB activation

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Gingerol, isoproterenol and ouabain normalize impaired post-rest behavior but not force-frequency relation in failing human myocardium

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Differential colorectal carcinogenesis: Molecular basis and clinical relevance

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Metabolism of [6]-gingerol in rats

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Targeting specific cell signaling transduction pathways by dietary and medicinal phytochemicals in cancer chemoprevention

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

[6]-Gingerol induces reactive oxygen species regulated mitochondrial cell death pathway in human epidermoid carcinoma A431 cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Induction of apoptosis by [6]-gingerol associated with the modulation of p53 and involvement of mitochondrial signaling pathway in B[a]P-induced mouse skin tumorigenesis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Effective anti-platelet and COX-1 enzyme inhibitors from pungent constituents of ginger

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Analgesic, antiinflammatory and hypoglycaemic effects of ethanol extract of Zingiber officinale (Roscoe) rhizomes (Zingiberaceae) in mice and rats

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Chemopreventive effects of natural dietary compounds on cancer development

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Botanicals in cancer chemoprevention

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Inhibitory effects of [6]-gingerol, a major pungent principle of ginger, on phorbol ester-induced inflammation, epidermal ornithine decarboxylase activity and skin tumor promotion in ICR mice.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Antibacterial activity of [10]-gingerol and [12]-gingerol isolated from ginger rhizome against periodontal bacteria

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Effect of [6]-gingerol on myofibroblast differentiation in transforming growth factor beta 1-induced nasal polyp-derived fibroblasts

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

[6]-Gingerol induces cell cycle arrest and cell death of mutant p53-expressing pancreatic cancer cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

[6]-gingerol as a cancer chemopreventive agent: a review of its activity on different steps of the metastatic process

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Ginger and its constituents: role in prevention and treatment of gastrointestinal cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

[6]-Gingerol induces caspase-dependent apoptosis and prevents PMA-induced proliferation in colon cancer cells by inhibiting MAPK/AP-1 signaling

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Biosynthesis of curcuminoids and gingerols in turmeric (Curcuma longa) and ginger (Zingiber officinale): Identification of curcuminoid synthase and hydroxycinnamoyl-CoA thioesterases

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Apoptosis-regulating proteins as targets for drug discovery

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Ginger inhibits cell growth and modulates angiogenic factors in ovarian cancer cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

[10]-Gingerol induces mitochondrial apoptosis through activation of MAPK pathway in HCT116 human colon cancer cells.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Helicobacter pylori and gastric cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Gingerols and shogaols: Important nutraceutical principles from ginger

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Cancer preventive properties of ginger: a brief review

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

The activation of Akt/PKB signaling pathway and cell survival.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Cyclooxygenase 2: a molecular target for cancer prevention and treatment

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Chemoprotective properties of some pungent ingredients present in red pepper and ginger.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Enzymic reduction of [6]-gingerol, a major pungent principle of ginger, in the cell-free preparation of rat liver

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Combined ginger extract & Gelam honey modulate Ras/ERK and PI3K/AKT pathway genes in colon cancer HT29 cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

The importance of using scientific principles in the development of medicinal agents from plants

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Modulation of Wnt/β-catenin signaling pathway by bioactive food components

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Effects of ginger and its constituents on airway smooth muscle relaxation and calcium regulation

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

p53 function and dysfunction

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Cytotoxic and apoptotic activities of diarylheptanoids and gingerol-related compounds from the rhizome of Chinese ginger

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Anti-invasion effects of 6-shogaol and 6-gingerol, two active components in ginger, on human hepatocarcinoma cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Molecular mechanism inhibiting human hepatocarcinoma cell invasion by 6-shogaol and 6-gingerol.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Gingerol content of diploid and tetraploid clones of ginger (Zingiber officinale Roscoe).

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Dysregulation and crosstalk of cellular signaling pathways in colon carcinogenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Inhibitory effect of gingerol on the proliferation and invasion of hepatoma cells in culture

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

6-Gingerol induces apoptosis through lysosomal-mitochondrial axis in human hepatoma G2 cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Genotoxic effect of 6-gingerol on human hepatoma G2 cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Molecular targets of dietary polyphenols with anti-inflammatory properties

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Modifying effects of fungal and herb metabolites on azoxymethane-induced intestinal carcinogenesis in rats

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Zerumbone, a Southeast Asian Ginger Sesquiterpene, Induced Apoptosis of Pancreatic Carcinoma Cells through p53 Signaling Pathway

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Pharmacokinetics of 6-gingerol, 8-gingerol, 10-gingerol, and 6-shogaol and conjugate metabolites in healthy human subjects

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

Pilot clinical study of the effects of ginger root extract on eicosanoids in colonic mucosa of subjects at increased risk for colorectal cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41342-6_8

10.1007/978-3-319-41342-6_8

31 March 2020

Identifiers

DOI

0 references

PubMed ID

27771925

1 reference

PubMed ID

27771925