Ex vivo drug response profiling detects recurrent sensitivity patterns in drug-resistant acute lymphoblastic leukemia. (Q38999126)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28122742%20AND%20SRC:MED&resulttype=core&format=json

9 April 2020

title

Ex vivo drug response profiling detects recurrent sensitivity patterns in drug-resistant acute lymphoblastic leukemia (English)

1 reference

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9 April 2020

17

1 reference

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Paulina Richter-Pechanska

9 April 2020

7

1 reference

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9 April 2020

Timothy J Brown

13

1 reference

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9 April 2020

Vaskar Saha

28

1 reference

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9 April 2020

Beat C Bornhauser

36

1 reference

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9 April 2020

Jean-Pierre Bourquin

37

1 reference

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9 April 2020

27

Martina U Muckenthaler

1 reference

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9 April 2020

author name string

Viktoras Frismantas

1

1 reference

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9 April 2020

Maria Pamela Dobay

2

1 reference

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9 April 2020

Anna Rinaldi

3

1 reference

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9 April 2020

Joelle Tchinda

4

1 reference

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9 April 2020

Samuel H Dunn

5

1 reference

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9 April 2020

Joachim Kunz

6

1 reference

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9 April 2020

Blerim Marovca

8

1 reference

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9 April 2020

Orrin Pail

9

1 reference

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9 April 2020

Silvia Jenni

10

1 reference

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9 April 2020

Ernesto Diaz-Flores

11

1 reference

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9 April 2020

Bill H Chang

12

1 reference

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9 April 2020

Robert H Collins

14

1 reference

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9 April 2020

Sebastian Uhrig

15

1 reference

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9 April 2020

Gnana P Balasubramanian

16

1 reference

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9 April 2020

Salome Higi

18

1 reference

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9 April 2020

Sabrina Eugster

19

1 reference

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9 April 2020

Pamela Voegeli

20

1 reference

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9 April 2020

Mauro Delorenzi

21

1 reference

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9 April 2020

Gunnar Cario

22

1 reference

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9 April 2020

Mignon L Loh

23

1 reference

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9 April 2020

Andreas E Kulozik

26

1 reference

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9 April 2020

Julie A Irving

29

1 reference

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9 April 2020

Roland Meisel

30

1 reference

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9 April 2020

Thomas Radimerski

31

1 reference

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9 April 2020

Arend Von Stackelberg

32

1 reference

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9 April 2020

Cornelia Eckert

33

1 reference

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9 April 2020

Jeffrey W Tyner

34

1 reference

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9 April 2020

Peter Horvath

35

1 reference

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9 April 2020

Martin Schrappe

24

1 reference

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9 April 2020

Martin Stanulla

25

1 reference

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9 April 2020

language of work or name

English

0 references

publication date

25 January 2017

1 reference

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9 April 2020

1 reference

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9 April 2020

volume

129

1 reference

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9 April 2020

issue

11

1 reference

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9 April 2020

page(s)

e26-e37

1 reference

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Efficacy and Biological Correlates of Response in a Phase II Study of Venetoclax Monotherapy in Patients with Acute Myelogenous Leukemia

9 April 2020

cites work

1 reference

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A review of new agents evaluated against pediatric acute lymphoblastic leukemia by the Pediatric Preclinical Testing Program.

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Patient-derived xenotransplants can recapitulate the genetic driver landscape of acute leukemias.

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Venetoclax responses of pediatric ALL xenografts reveal sensitivity of MLL-rearranged leukemia.

17 June 2018

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The Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in Mice

17 June 2018

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New and emerging prognostic and predictive genetic biomarkers in B-cell precursor acute lymphoblastic leukemia

17 June 2018

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Expression Profile of BCL-2, BCL-XL, and MCL-1 Predicts Pharmacological Response to the BCL-2 Selective Antagonist Venetoclax in Multiple Myeloma Models

17 June 2018

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High-throughput screening using patient-derived tumor xenografts to predict clinical trial drug response.

17 June 2018

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Genomics and drug profiling of fatal TCF3-HLF-positive acute lymphoblastic leukemia identifies recurrent mutation patterns and therapeutic options

17 June 2018

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Self-enforcing feedback activation between BCL6 and pre-B cell receptor signaling defines a distinct subtype of acute lymphoblastic leukemia

17 June 2018

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Monitoring minimal residual disease in children with high-risk relapses of acute lymphoblastic leukemia: prognostic relevance of early and late assessment

17 June 2018

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Drug-induced death signaling strategy rapidly predicts cancer response to chemotherapy.

17 June 2018

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Axitinib effectively inhibits BCR-ABL1(T315I) with a distinct binding conformation

17 June 2018

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BH3 Inhibitor Sensitivity and Bcl-2 Dependence in Primary Acute Lymphoblastic Leukemia Cells.

17 June 2018

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Monitoring of minimal residual disease after allogeneic stem-cell transplantation in relapsed childhood acute lymphoblastic leukemia allows for the identification of impending relapse: results of the ALL-BFM-SCT 2003 trial

17 June 2018

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Image-based RNA interference screening reveals an individual dependence of acute lymphoblastic leukemia on stromal cysteine support.

17 June 2018

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ABT-199 mediated inhibition of BCL-2 as a novel therapeutic strategy in T-cell acute lymphoblastic leukemia

17 June 2018

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Ras pathway mutations are prevalent in relapsed childhood acute lymphoblastic leukemia and confer sensitivity to MEK inhibition

17 June 2018

1 reference

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Targetable kinase-activating lesions in Ph-like acute lymphoblastic leukemia

17 June 2018

1 reference

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Cell and molecular determinants of in vivo efficacy of the BH3 mimetic ABT-263 against pediatric acute lymphoblastic leukemia xenografts

17 June 2018

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Maturation stage of T-cell acute lymphoblastic leukemia determines BCL-2 versus BCL-XL dependence and sensitivity to ABT-199

17 June 2018

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Niche-based screening identifies small-molecule inhibitors of leukemia stem cells

17 June 2018

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Acute lymphoblastic leukaemia

17 June 2018

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The role of tumour-stromal interactions in modifying drug response: challenges and opportunities

17 June 2018

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The genomic landscape of hypodiploid acute lymphoblastic leukemia

17 June 2018

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ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets

17 June 2018

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Crosstalk between ROR1 and the Pre-B cell receptor promotes survival of t(1;19) acute lymphoblastic leukemia

17 June 2018

1 reference

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Kinase pathway dependence in primary human leukemias determined by rapid inhibitor screening

17 June 2018

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Outcomes after induction failure in childhood acute lymphoblastic leukemia

17 June 2018

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The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

17 June 2018

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Systematic identification of genomic markers of drug sensitivity in cancer cells

17 June 2018

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Pretreatment mitochondrial priming correlates with clinical response to cytotoxic chemotherapy

17 June 2018

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Thiazolyl N-benzyl-substituted acetamide derivatives: synthesis, Src kinase inhibitory and anticancer activities

17 June 2018

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Mutations and deletions of the TP53 gene predict nonresponse to treatment and poor outcome in first relapse of childhood acute lymphoblastic leukemia

17 June 2018

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Gain-of-function mutations in interleukin-7 receptor-α (IL7R) in childhood acute lymphoblastic leukemias

17 June 2018

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Effect of mitoxantrone on outcome of children with first relapse of acute lymphoblastic leukaemia (ALL R3): an open-label randomised trial

17 June 2018

1 reference

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Induction of autophagy-dependent necroptosis is required for childhood acute lymphoblastic leukemia cells to overcome glucocorticoid resistance

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5356455

Drug combination studies and their synergy quantification using the Chou-Talalay method

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5356455

Therapeutic targeting of MLL.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5356455

Mesenchymal cells regulate the response of acute lymphoblastic leukemia cells to asparaginase

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5356455

Dasatinib (BMS-354825) pharmacokinetics and pharmacodynamic biomarkers in animal models predict optimal clinical exposure

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5356455

ERBB receptors and cancer: the complexity of targeted inhibitors

17 June 2018

1 reference

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Development and functional characterization of human bone marrow mesenchymal cells immortalized by enforced expression of telomerase

17 June 2018

1 reference

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Bone marrow-derived stromal cells prevent apoptotic cell death in B-lineage acute lymphoblastic leukemia

17 June 2018

1 reference

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Activation of concurrent apoptosis and necroptosis by SMAC mimetics for the treatment of refractory and relapsed ALL.

17 June 2018

1 reference

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Individualized systems medicine strategy to tailor treatments for patients with chemorefractory acute myeloid leukemia.

21 August 2018

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Dasatinib in children and adolescents with relapsed or refractory leukemia: results of the CA180-018 phase I dose-escalation study of the Innovative Therapies for Children with Cancer Consortium

21 August 2018

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Leukemia surfaceome analysis reveals new disease-associated features.

21 August 2018

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Dasatinib as first-line treatment for adult patients with Philadelphia chromosome-positive acute lymphoblastic leukemia.

21 August 2018

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Xenografts of highly resistant leukemia recapitulate the clonal composition of the leukemogenic compartment.

21 August 2018

1 reference

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Molecular response to treatment redefines all prognostic factors in children and adolescents with B-cell precursor acute lymphoblastic leukemia: results in 3184 patients of the AIEOP-BFM ALL 2000 study

21 August 2018

1 reference

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Rapid complete cytogenetic remission after upfront dasatinib monotherapy in a patient with a NUP214-ABL1-positive T-cell acute lymphoblastic leukemia

21 August 2018

1 reference

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Patient stratification based on prednisolone-vincristine-asparaginase resistance profiles in children with acute lymphoblastic leukemia

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5356455

Two types of genomic rearrangements create alternative E2A-HLF fusion proteins in t(17;19)-ALL

21 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28122742

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

How I treat relapsed childhood acute lymphoblastic leukemia

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28122742

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1182/BLOOD-2016-09-738070

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28122742%20AND%20SRC:MED&resulttype=core&format=json

9 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28122742%20AND%20SRC:MED&resulttype=core&format=json

9 April 2020

PubMed publication ID

28122742

1 reference