Wnt signaling and cellular metabolism in osteoblasts (Q39020338)

19 May 2018

review article

1 reference

title

Wnt signaling and cellular metabolism in osteoblasts (English)

1 reference

19 May 2018

0 references

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27888287%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Fanxin Long

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27888287%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

author name string

Courtney M Karner

series ordinal

1

1 reference

19 May 2018

Fanxin Long

series ordinal

2

1 reference

19 May 2018

publication date

26 November 2016

1 reference

19 May 2018

Cellular and Molecular Life Sciences

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27888287%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

volume

74

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27888287%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

issue

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27888287%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

page(s)

1649-1657

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27888287%20AND%20SRC:MED&resulttype=core&format=json

Mechanisms of diabetes mellitus-induced bone fragility

6 June 2020

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17 June 2018

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17 June 2018

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17 June 2018

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17 June 2018

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17 June 2018

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mTORC2 signaling promotes skeletal growth and bone formation in mice

17 June 2018

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Up-regulation of glycolytic metabolism is required for HIF1α-driven bone formation

17 June 2018

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Wnt signaling directs a metabolic program of glycolysis and angiogenesis in colon cancer

17 June 2018

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The swaying mouse as a model of osteogenesis imperfecta caused by WNT1 mutations

17 June 2018

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Tsc2 is a molecular checkpoint controlling osteoblast development and glucose homeostasis

17 June 2018

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Bioenergetics during calvarial osteoblast differentiation reflect strain differences in bone mass

17 June 2018

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BCAT1 promotes cell proliferation through amino acid catabolism in gliomas carrying wild-type IDH1.

17 June 2018

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Lrp5 and Lrp6 exert overlapping functions in osteoblasts during postnatal bone acquisition

17 June 2018

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WNT1 mutations in early-onset osteoporosis and osteogenesis imperfecta

17 June 2018

1 reference

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ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death.

17 June 2018

1 reference

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WNT-LRP5 signaling induces Warburg effect through mTORC2 activation during osteoblast differentiation.

17 June 2018

1 reference

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Canonical Wnt signaling inhibits osteoclastogenesis independent of osteoprotegerin

17 June 2018

1 reference

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β-catenin promotes bone formation and suppresses bone resorption in postnatal growing mice

17 June 2018

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Gpr177, a novel locus for bone mineral density and osteoporosis, regulates osteogenesis and chondrogenesis in skeletal development

17 June 2018

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WNT16 influences bone mineral density, cortical bone thickness, bone strength, and osteoporotic fracture risk

17 June 2018

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Wnt5a can both activate and repress Wnt/β-catenin signaling during mouse embryonic development

17 June 2018

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Wntless functions in mature osteoblasts to regulate bone mass

17 June 2018

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Loss of wnt/β-catenin signaling causes cell fate shift of preosteoblasts from osteoblasts to adipocytes

17 June 2018

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Matrix IGF-1 maintains bone mass by activation of mTOR in mesenchymal stem cells

17 June 2018

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Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture

17 June 2018

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Building strong bones: molecular regulation of the osteoblast lineage

17 June 2018

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mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H(+)-ATPase

17 June 2018

1 reference

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Wnt antagonists bind through a short peptide to the first β-propeller domain of LRP5/6

17 June 2018

1 reference

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Lrp5 functions in bone to regulate bone mass

17 June 2018

1 reference

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Control of bone formation by the serpentine receptor Frizzled-9

17 June 2018

1 reference

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Wnt signaling requires sequestration of glycogen synthase kinase 3 inside multivesicular endosomes

17 June 2018

1 reference

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Endoplasmic reticulum stress response mediated by the PERK-eIF2(alpha)-ATF4 pathway is involved in osteoblast differentiation induced by BMP2

17 June 2018

1 reference

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Stimulation of glucose transport in osteoblastic cells by parathyroid hormone and insulin-like growth factor I

17 June 2018

1 reference

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Glutamate preferentially suppresses osteoblastogenesis than adipogenesis through the cystine/glutamate antiporter in mesenchymal stem cells

17 June 2018

1 reference

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Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies

17 June 2018

1 reference

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Dependence of mouse embryonic stem cells on threonine catabolism

17 June 2018

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Genetic control of bone formation

17 June 2018

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ATP-citrate lyase links cellular metabolism to histone acetylation

17 June 2018

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Understanding the Warburg effect: the metabolic requirements of cell proliferation

17 June 2018

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17 June 2018

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Bidirectional transport of amino acids regulates mTOR and autophagy

17 June 2018

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Bone mineral density, osteoporosis, and osteoporotic fractures: a genome-wide association study.

17 June 2018

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Rac1 activation controls nuclear localization of beta-catenin during canonical Wnt signaling.

17 June 2018

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17 June 2018

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17 June 2018

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Noncanonical Wnt signaling through G protein-linked PKCdelta activation promotes bone formation

17 June 2018

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17 June 2018

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ATF4 mediation of NF1 functions in osteoblast reveals a nutritional basis for congenital skeletal dysplasiae

17 June 2018

1 reference

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TSC2 integrates Wnt and energy signals via a coordinated phosphorylation by AMPK and GSK3 to regulate cell growth

17 June 2018

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Differential expression and functional characterization of system L amino acid transporters in human normal osteoblast cells and osteogenic sarcoma cells

17 June 2018

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Mice lacking brain/kidney phosphate-activated glutaminase have impaired glutamatergic synaptic transmission, altered breathing, disorganized goal-directed behavior and die shortly after birth

17 June 2018

1 reference

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Purified Wnt5a protein activates or inhibits beta-catenin-TCF signaling depending on receptor context

17 June 2018

1 reference

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Histone demethylation by a family of JmjC domain-containing proteins

17 June 2018

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SOST is a ligand for LRP5/LRP6 and a Wnt signaling inhibitor

17 June 2018

1 reference

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Canonical Wnt signaling in differentiated osteoblasts controls osteoclast differentiation

17 June 2018

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Wnt/beta-catenin signaling in mesenchymal progenitors controls osteoblast and chondrocyte differentiation during vertebrate skeletogenesis

17 June 2018

1 reference

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Canonical Wnt/beta-catenin signaling prevents osteoblasts from differentiating into chondrocytes

17 June 2018

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Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signaling pathways

17 June 2018

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Essential role of beta-catenin in postnatal bone acquisition

17 June 2018

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Regulation of osteoblastogenesis and bone mass by Wnt10b

17 June 2018

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Sequential roles of Hedgehog and Wnt signaling in osteoblast development

17 June 2018

1 reference

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Protein kinase A signalling via CREB controls myogenesis induced by Wnt proteins

17 June 2018

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The Wnt signaling pathway in development and disease

17 June 2018

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Mammalian Ryk is a Wnt coreceptor required for stimulation of neurite outgrowth

17 June 2018

1 reference

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ATF4 is a substrate of RSK2 and an essential regulator of osteoblast biology; implication for Coffin-Lowry Syndrome

17 June 2018

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17 June 2018

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Sclerostin is an osteocyte-expressed negative regulator of bone formation, but not a classical BMP antagonist

17 June 2018

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The Wnt antagonist secreted frizzled-related protein-1 is a negative regulator of trabecular bone formation in adult mice

17 June 2018

1 reference

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CELL POPULATION KINETICS OF AN OSTEOGENIC TISSUE. II

17 June 2018

1 reference

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High bone mass in mice expressing a mutant LRP5 gene

17 June 2018

1 reference

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Dishevelled activates Ca2+ flux, PKC, and CamKII in vertebrate embryos.

17 June 2018

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Coactivation of Rac and Rho by Wnt/Frizzled signaling is required for vertebrate gastrulation

17 June 2018

1 reference

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High bone density due to a mutation in LDL-receptor-related protein 5

17 June 2018

1 reference

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The PERK eukaryotic initiation factor 2 alpha kinase is required for the development of the skeletal system, postnatal growth, and the function and viability of the pancreas

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380548

Cbfa1-independent decrease in osteoblast proliferation, osteopenia, and persistent embryonic eye vascularization in mice deficient in Lrp5, a Wnt coreceptor

17 June 2018

1 reference

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Identification of a 52 kb deletion downstream of the SOST gene in patients with van Buchem disease

17 June 2018

1 reference

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Wnt/beta-catenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway

17 June 2018

1 reference

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The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation

17 June 2018

1 reference

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JNK functions in the non-canonical Wnt pathway to regulate convergent extension movements in vertebrates

17 June 2018

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A mutation in the LDL receptor-related protein 5 gene results in the autosomal dominant high-bone-mass trait

17 June 2018

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17 June 2018

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Head inducer Dickkopf-1 is a ligand for Wnt coreceptor LRP6

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380548

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380548

Bone dysplasia sclerosteosis results from loss of the SOST gene product, a novel cystine knot-containing protein

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380548

Inhibition of the Wnt signaling pathway by Idax, a novel Dvl-binding protein

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380548

Regulated translation initiation controls stress-induced gene expression in mammalian cells

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380548

naked cuticle encodes an inducible antagonist of Wnt signalling

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380548

Synergy between tumor suppressor APC and the beta-catenin-Tcf4 target Tcf1.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380548

Protein kinase C is differentially stimulated by Wnt and Frizzled homologs in a G-protein-dependent manner

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380548

Carnitine and dehydroepiandrosterone sulfate induce protein synthesis in porcine primary osteoblast-like cells

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380548

Missense mutations abolishing DNA binding of the osteoblast-specific transcription factor OSF2/CBFA1 in cleidocranial dysplasia.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380548

Purification and molecular cloning of a secreted, Frizzled-related antagonist of Wnt action

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380548

Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380548

Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380548

Frzb-1 is a secreted antagonist of Wnt signaling expressed in the Spemann organizer

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380548

A family of secreted proteins contains homology to the cysteine-rich ligand-binding domain of frizzled receptors

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380548

Functional interaction of beta-catenin with the transcription factor LEF-1

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380548

Structure and function of mammalian facilitative sugar transporters.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380548

Facilitative glucose transporters

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380548

A hierarchy of ATP-consuming processes in mammalian cells

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380548

Amino acid transport in bone: stimulation by cyclic AMP.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380548

Insulin effect on amino acid transport in bone: dependence on protein synthesis and Na+.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380548

Some properties of the stimulatory effect of thyroid hormones on amino acid transport by embryonic chick bone.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380548

Mechanism of mobilization of bone mineral by 1,25-dihydroxyvitamin D3

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380548

Aerobic glycolysis in bone: lactic acid production by rat calvaria cells in culture

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380548

Aging Reduces an ERRalpha-Directed Mitochondrial Glutaminase Expression Suppressing Glutamine Anaplerosis and Osteogenic Differentiation of Mesenchymal Stem Cells

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380548

HIF-1α Promotes Glutamine-Mediated Redox Homeostasis and Glycogen-Dependent Bioenergetics to Support Postimplantation Bone Cell Survival

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380548

Methionine metabolism regulates maintenance and differentiation of human pluripotent stem cells.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380548

WNT7B promotes bone formation in part through mTORC1.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380548

Glutaminolysis activates Rag-mTORC1 signaling.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380548

Absence of glutamine supplementation prevents differentiation of murine calvarial osteoblasts to a mineralizing phenotype

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380548

Negative regulation of osteoblastogenesis through downregulation of runt-related transcription factor-2 in osteoblastic MC3T3-E1 cells with stable overexpression of the cystine/glutamate antiporter xCT subunit.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380548

Comprehensive expression analysis of all Wnt genes and their major secreted antagonists during mouse limb development and cartilage differentiation.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380548

Targeted deletion of the sclerostin gene in mice results in increased bone formation and bone strength

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380548

Distinct roles for Hedgehog and canonical Wnt signaling in specification, differentiation and maintenance of osteoblast progenitors.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380548

Beta-catenin-sensitive isoforms of lymphoid enhancer factor-1 are selectively expressed in colon cancer

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380548

Bioenergetics and mitochondrial transmembrane potential during differentiation of cultured osteoblasts.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380548

Induction of osteoprogenitor cell differentiation in rat marrow stroma increases mitochondrial retention of rhodamine 123 in stromal cells

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380548

Fatty acid oxidation in bone tissue and bone cells in culture. Characterization and hormonal influences

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380548

Canonical WNT Signaling Promotes Osteogenesis by Directly StimulatingRunx2Gene Expression

21 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00018-016-2425-5

Deletion of a single allele of the Dkk1 gene leads to an increase in bone formation and bone mass

21 January 2018

1 reference

12 December 2020

Aerobic glycolysis in bone: lactate production and gradients in calvaria

1 reference

12 December 2020

A negative correlation between expression profiles of runt-related transcription factor-2 and cystine/glutamate antiporter xCT subunit in ovariectomized mouse bone

1 reference

12 December 2020

Characteristics of a neutral amino acid transport system (system A) in osteoblastic rat osteosarcoma cells

1 reference

12 December 2020

Ontogenesis of ultrastructural features during osteogenic differentiation in diffusion chamber cultures of marrow cells

1 reference

12 December 2020

Amino acid transport in bone. Evidence for separate transport systems for neutral amino and imino acids

1 reference

12 December 2020

Parathormone promotes glycogen formation from [14C]glucose in cultured osteoblast-like cells

1 reference

12 December 2020

Selective Alteration by Triiodothyronine of Amino Acid Transport in Embryonic Bone

1 reference

12 December 2020

Aerobic metabolism of glucose by bone

1 reference

12 December 2020

Amino acid transport in adult diaphyseal bone: contrast with amino acid transport mechanisms in fetal membranous bone

1 reference

12 December 2020

Uptake of postprandial lipoproteins into bone in vivo: impact on osteoblast function

1 reference

12 December 2020

Effect of parathyroid extract on the oxidation in vitro of glucose and the production of 14CO2 by bone and kidney

1 reference

12 December 2020

Growth of rat osteoblast-like cells in a lipid-enriched culture medium and regulation of function by parathyroid hormone and 1,25-dihydroxyvitamin D

1 reference

12 December 2020

PTH Promotes Bone Anabolism by Stimulating Aerobic Glycolysis via IGF Signaling

1 reference

12 December 2020

Further Studies of Amino Acid Transport by Embryonic Chick Bone

1 reference

12 December 2020

Metabolic studies of bone in vitro. I. Normal bone

1 reference

12 December 2020

Effect of parathyroid hormone on amino acid transport by cultured neonatal mouse calvarial bone cells

1 reference

12 December 2020

Mutations in WNT1 are a cause of osteogenesis imperfecta

1 reference

12 December 2020

Insulin effect on amino acid transport in bone

1 reference

12 December 2020

Glutamine metabolism in bone

1 reference

12 December 2020

10.1007/S00018-016-2425-5

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27888287%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27888287%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

PubMed publication ID

27888287

1 reference