Quantitative Proteome Analysis of Mouse Liver Lysosomes Provides Evidence for Mannose 6-phosphate-independent Targeting Mechanisms of Acid Hydrolases in Mucolipidosis II. (Q39034834)

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scientific article published on 6 January 2017

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English	Quantitative Proteome Analysis of Mouse Liver Lysosomes Provides Evidence for Mannose 6-phosphate-independent Targeting Mechanisms of Acid Hydrolases in Mucolipidosis II.	scientific article published on 6 January 2017

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5 April 2020

Quantitative Proteome Analysis of Mouse Liver Lysosomes Provides Evidence for Mannose 6-phosphate-independent Targeting Mechanisms of Acid Hydrolases in Mucolipidosis II (English)

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5 April 2020

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Sandra Markmann

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Svenja Krambeck

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Christopher J Hughes

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Mina Mirzaian

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Michaela Schweizer

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Johannes P C Vissers

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Thomas Braulke

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6 January 2017

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Molecular & Cellular Proteomics

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3

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438-450

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describes a project that uses

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The position of lysosomes within the cell determines their luminal pH

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Cathepsin D and its newly identified transport receptor SEZ6L2 can modulate neurite outgrowth

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Subunit interactions of the disease-related hexameric GlcNAc-1-phosphotransferase complex.

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Prosaposin facilitates sortilin-independent lysosomal trafficking of progranulin

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BORC, a multisubunit complex that regulates lysosome positioning.

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Decreased bone formation and increased osteoclastogenesis cause bone loss in mucolipidosis II.

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An extended proteome map of the lysosomal membrane reveals novel potential transporters

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Lysosomal dysfunction causes neurodegeneration in mucolipidosis II 'knock-in' mice

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Mannose 6-phosphate receptor and sortilin mediated endocytosis of α-galactosidase A in kidney endothelial cells

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17 June 2018

Sortilin-mediated endocytosis determines levels of the frontotemporal dementia protein, progranulin.

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The proteome of lysosomes

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17 June 2018

Pro-cathepsin D interacts with the extracellular domain of the beta chain of LRP1 and promotes LRP1-dependent fibroblast outgrowth.

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Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids

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17 June 2018

Functions of the alpha, beta, and gamma subunits of UDP-GlcNAc:lysosomal enzyme N-acetylglucosamine-1-phosphotransferase

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17 June 2018

Impaired lysosomal trimming of N-linked oligosaccharides leads to hyperglycosylation of native lysosomal proteins in mice with alpha-mannosidosis

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17 June 2018

Proteomics of the lysosome

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17 June 2018

LIMP-2 is a receptor for lysosomal mannose-6-phosphate-independent targeting of beta-glucocerebrosidase

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17 June 2018

Murine UDP-GlcNAc:lysosomal enzyme N-acetylglucosamine-1-phosphotransferase lacking the gamma-subunit retains substantial activity toward acid hydrolases

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17 June 2018

Endocytosis provides a major alternative pathway for lysosomal biogenesis in kidney proximal tubular cells

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Retrograde transport from endosomes to the trans-Golgi network

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Absolute quantification of proteins by LCMSE: a virtue of parallel MS acquisition

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Proteomic analysis of lysosomal acid hydrolases secreted by osteoclasts: implications for lytic enzyme transport and bone metabolism

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Mucolipidosis II is caused by mutations in GNPTA encoding the alpha/beta GlcNAc-1-phosphotransferase

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17 June 2018

The alpha- and beta-subunits of the human UDP-N-acetylglucosamine:lysosomal enzyme N-acetylglucosamine-1-phosphotransferase [corrected] are encoded by a single cDNA.

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The human brain mannose 6-phosphate glycoproteome: a complex mixture composed of multiple isoforms of many soluble lysosomal proteins

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The lysosomal trafficking of sphingolipid activator proteins (SAPs) is mediated by sortilin

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17 June 2018

Mannose 6-phosphate receptors: new twists in the tale

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Mannose receptor-mediated regulation of serum glycoprotein homeostasis

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Mannose 6-phosphate-independent targeting of lysosomal enzymes in I-cell disease B lymphoblasts

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Lysosomal enzyme targeting. N-Acetylglucosaminylphosphotransferase selectively phosphorylates native lysosomal enzymes

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UDP-N-acetylglucosamine:lysosomal enzyme precursor N-acetylglucosamine-1-phosphotransferase. Partial purification and characterization of the rat liver Golgi enzyme

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Is movement of mannose 6-phosphate-specific receptor triggered by binding of lysosomal enzymes?

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17 June 2018

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17 June 2018

Clearance of lysosomal hydrolases following intravenous infusion. The role of liver in the clearance of beta-glucuronidase and N-acetyl-beta-D-glucosaminidase

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17 June 2018

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17 June 2018

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21 August 2018

Biosynthesis, targeting, and processing of lysosomal proteins: pulse-chase labeling and immune precipitation

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21 August 2018

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21 August 2018

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21 August 2018

Tolerogenic maturation of liver sinusoidal endothelial cells promotes B7-homolog 1-dependent CD8+ T cell tolerance

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21 January 2018

Identification of a rat liver alpha-N-acetylglucosaminyl phosphodiesterase capable of removing “blocking” alpha-N-acetylglucosamine residues from phosphorylated high mannose oligosaccharides of lysosomal enzymes

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12 December 2020

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Proteomics analysis of serum from mutant mice reveals lysosomal proteins selectively transported by each of the two mannose 6-phosphate receptors

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12 December 2020

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Proteolysis of Insulin-Like Growth Factors (IGF) and IGF Binding Proteins by Cathepsin D1

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12 December 2020

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inferred from PubMed ID database lookup

Rat hepatocytes prepared without collagenase: prolonged retention of differentiated characteristics in culture

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biosynthesis of cathepsin B in cultured normal and I-cell fibroblasts

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12 December 2020

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inferred from PubMed ID database lookup

The mucolipidoses: identification by abnormal electrophoretic patterns of lysosomal hydrolases

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Is there a mechanism for introducing acid hydrolases into liver lysosomes that is independent of mannose 6-phosphate recognition? Evidence from I-cell disease

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12 December 2020

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Bovine UDP-N-acetylglucosamine:lysosomal-enzyme N-acetylglucosamine-1-phosphotransferase. I. Purification and subunit structure

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12 December 2020

based on heuristic

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Identifiers

10.1074/MCP.M116.063636

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