Prodomain of the proprotein convertase subtilisin/kexin Furin (ppFurin) protects from tumor progression and metastasis (Q39078284)

8 September 2017

title

Prodomain of the proprotein convertase subtilisin/kexin Furin (ppFurin) protects from tumor progression and metastasis (English)

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8 September 2017

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Nabil Seidah

5

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author name string

Nathalie Scamuffa

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8 September 2017

Fatma Sfaxi

2

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8 September 2017

Jia Ma

3

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8 September 2017

Claude Lalou

4

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8 September 2017

Fabien Calvo

6

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Abdel-Majid Khatib

7

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8 September 2017

language of work or name

English

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publication date

14 October 2013

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8 September 2017

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8 September 2017

volume

35

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8 September 2017

issue

3

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8 September 2017

page(s)

528-536

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The biology and therapeutic targeting of the proprotein convertases

8 September 2017

cites work

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGT345

Role of proprotein convertases in prostate cancer progression

21 January 2018

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Proprotein convertases: "master switches" in the regulation of tumor growth and progression

21 January 2018

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Proprotein convertases in tumor progression and malignancy: novel targets in cancer therapy

21 January 2018

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Blockade of furin activity and furin-induced tumor cells malignant phenotypes by the chemically synthesized human furin prodomain

21 January 2018

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Inhibition of proprotein convertases is associated with loss of growth and tumorigenicity of HT-29 human colon carcinoma cells: importance of insulin-like growth factor-1 (IGF-1) receptor processing in IGF-1-mediated functions

21 January 2018

1 reference

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Selective inhibition of proprotein convertases represses the metastatic potential of human colorectal tumor cells

21 January 2018

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Inhibition of the proprotein convertases represses the invasiveness of human primary melanoma cells with altered p53, CDKN2A and N-Ras genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGT345

Inhibitory feature of the proprotein convertases prosegments.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGT345

The prosegments of furin and PC7 as potent inhibitors of proprotein convertases. In vitro and ex vivo assessment of their efficacy and selectivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGT345

Post-translational processing of beta-secretase (beta-amyloid-converting enzyme) and its ectodomain shedding. The pro- and transmembrane/cytosolic domains affect its cellular activity and amyloid-beta production

21 January 2018

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A novel enediynyl peptide inhibitor of furin that blocks processing of proPDGF-A, B and proVEGF-C.

21 January 2018

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Potential opportunity in the development of new therapeutic agents based on endogenous and exogenous inhibitors of the proprotein convertases

21 January 2018

1 reference

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Regulation of the stepwise proteolytic cleavage and secretion of PDGF-B by the proprotein convertases

21 January 2018

1 reference

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Cell signaling by receptor tyrosine kinases

21 January 2018

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Opposing function of the proprotein convertases furin and PACE4 on breast cancer cells' malignant phenotypes: role of tissue inhibitors of metalloproteinase-1.

21 January 2018

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Phase I trial of "bi-shRNAi(furin)/GMCSF DNA/autologous tumor cell" vaccine (FANG) in advanced cancer

21 January 2018

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The IGF-I receptor in cancer research

21 January 2018

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Autocrine PDGF stimulation in malignancies

21 January 2018

1 reference

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Human carcinoma cell growth and invasiveness is impaired by the propeptide of the ubiquitous proprotein convertase furin

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGT345

Inhibition of proprotein convertases enhances cell migration and metastases development of human colon carcinoma cells in a rat model

21 January 2018

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RNAi-mediated gene silencing in non-human primates.

21 January 2018

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21 January 2018

Identifiers

DOI

10.1093/CARCIN/BGT345

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8 September 2017

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