Implications of Resveratrol on Glucose Uptake and Metabolism. (Q39168097)

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5 April 2020

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19 July 2022

Implications of Resveratrol on Glucose Uptake and Metabolism (English)

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8 April 2021

David León

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Elena Uribe

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Angara Zambrano

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Mónica Salas

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7 March 2017

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Creative Commons Attribution

5 April 2020

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2 references

8 April 2021

19 July 2022

0 references

Cancer chemopreventive activity of resveratrol, a natural product derived from grapes

1 reference

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Resveratrol and inflammation: Challenges in translating pre-clinical findings to improved patient outcomes

21 January 2018

1 reference

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Antioxidant effects of resveratrol and other stilbene derivatives on oxidative stress and *NO bioavailability: Potential benefits to cardiovascular diseases

21 January 2018

1 reference

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Resveratrol induces apoptosis involving mitochondrial pathways in mouse skin tumorigenesis

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1 reference

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Anti-proliferative and gene expression actions of resveratrol in breast cancer cells in vitro

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Resveratrol and cancer: focus on in vivo evidence

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Resveratrol: Biological and pharmaceutical properties as anticancer molecule

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Understanding the Warburg effect: the metabolic requirements of cell proliferation

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Over-expression of facilitative glucose transporter genes in human cancer.

21 January 2018

1 reference

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GLUT-1 expression in ovarian carcinoma: association with survival and response to chemotherapy.

21 January 2018

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A small-molecule inhibitor of glucose transporter 1 downregulates glycolysis, induces cell-cycle arrest, and inhibits cancer cell growth in vitro and in vivo.

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Small compound inhibitors of basal glucose transport inhibit cell proliferation and induce apoptosis in cancer cells via glucose-deprivation-like mechanisms

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High absorption but very low bioavailability of oral resveratrol in humans

21 January 2018

1 reference

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Bioavailability of trans-resveratrol from red wine in humans.

21 January 2018

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Properties of Resveratrol: In Vitro and In Vivo Studies about Metabolism, Bioavailability, and Biological Effects in Animal Models and Humans

21 January 2018

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Anticancer Efficacy of Polyphenols and Their Combinations

21 January 2018

1 reference

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Cisplatin and resveratrol induce apoptosis and autophagy following oxidative stress in malignant mesothelioma cells

21 January 2018

1 reference

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Resveratrol improves insulin signaling in a tissue-specific manner under insulin-resistant conditions only: in vitro and in vivo experiments in rodents

21 January 2018

1 reference

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High-dose resveratrol supplementation in obese men: an investigator-initiated, randomized, placebo-controlled clinical trial of substrate metabolism, insulin sensitivity, and body composition.

21 January 2018

1 reference

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Effect of resveratrol on glucose control and insulin sensitivity: a meta-analysis of 11 randomized controlled trials

21 January 2018

1 reference

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Diabetes treatment in 2025: can scientific advances keep pace with prevalence?

21 January 2018

1 reference

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Banting Lecture. From the triumvirate to the ominous octet: a new paradigm for the treatment of type 2 diabetes mellitus

21 January 2018

1 reference

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Regulation and function of AMPK in physiology and diseases

21 January 2018

1 reference

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AMP-activated protein kinase and muscle glucose uptake

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030398

Activation of the glucose transporter GLUT4 by insulin

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030398

Activators of AMP-activated protein kinase enhance GLUT4 translocation and its glucose transport activity in 3T3-L1 adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030398

Stimulation of muscle cell glucose uptake by resveratrol through sirtuins and AMPK.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030398

The Impact of Resveratrol Supplementation on Blood Glucose, Insulin, Insulin Resistance, Triglyceride, and Periodontal Markers in Type 2 Diabetic Patients with Chronic Periodontitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030398

Caveolin-3 is involved in the protection of resveratrol against high-fat-diet-induced insulin resistance by promoting GLUT4 translocation to the plasma membrane in skeletal muscle of ovariectomized rats

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030398

Antihyperglycemic effects of short term resveratrol supplementation in type 2 diabetic patients

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030398

Pilot study of resveratrol in older adults with impaired glucose tolerance.

21 January 2018

1 reference

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Effects of resveratrol in patients with type 2 diabetes mellitus on skeletal muscle SIRT1 expression and energy expenditure

21 January 2018

1 reference

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Expression of glucose transporters in cancers

21 January 2018

1 reference

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Metabolic phenotype of bladder cancer

21 January 2018

1 reference

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Facilitative glucose transporters: Implications for cancer detection, prognosis and treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030398

Resveratrol-induced autophagocytosis in ovarian cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030398

Resveratrol inhibits glucose metabolism in human ovarian cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030398

Cancer-specific interruption of glucose metabolism by resveratrol is mediated through inhibition of Akt/GLUT1 axis in ovarian cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030398

Resveratrol decreases breast cancer cell viability and glucose metabolism by inhibiting 6-phosphofructo-1-kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030398

Resveratrol inhibits cancer cell metabolism by down regulating pyruvate kinase M2 via inhibition of mammalian target of rapamycin

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030398

Resveratrol suppresses cancer cell glucose uptake by targeting reactive oxygen species-mediated hypoxia-inducible factor-1α activation

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030398

Kinetics of transport and phosphorylation of glucose in cancer cells.

21 January 2018

1 reference

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Resolution of the direct interaction with and inhibition of the human GLUT1 hexose transporter by resveratrol from its effect on glucose accumulation

21 January 2018

1 reference

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Crystal structure of the human glucose transporter GLUT1

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030398

Resveratrol regulates gene transcription via activation of stimulus-responsive transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030398

Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030398

Resveratrol ameliorates aging-related metabolic phenotypes by inhibiting cAMP phosphodiesterases

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030398

SIRT1 transgenic mice show phenotypes resembling calorie restriction

21 January 2018

1 reference

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SirT1 gain of function increases energy efficiency and prevents diabetes in mice

21 January 2018

1 reference

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Diverse roles of SIRT1 in cancer biology and lipid metabolism

21 January 2018

1 reference

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Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha

21 January 2018

1 reference

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AMP-activated protein kinase and its downstream transcriptional pathways

21 January 2018

1 reference

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Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1

21 January 2018

1 reference

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The molecular targets of resveratrol

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030398

Modulation of SIRT1-Foxo1 signaling axis by resveratrol: implications in skeletal muscle aging and insulin resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030398

Resveratrol stimulates AMP kinase activity in neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030398

Resveratrol stimulates glucose transport in C2C12 myotubes by activating AMP-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030398

AMPK: a nutrient and energy sensor that maintains energy homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030398

Cross-talk between AMPK and mTOR in regulating energy balance

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030398

Rapalogs and mTOR inhibitors as anti-aging therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030398

Resveratrol inhibits protein translation in hepatic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030398

TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030398

The RSK family of kinases: emerging roles in cellular signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030398

AMPK phosphorylation of raptor mediates a metabolic checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030398

Resveratrol directly targets DDX5 resulting in suppression of the mTORC1 pathway in prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030398

Anticancer Molecular Mechanisms of Resveratrol

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030398

Resveratrol is a class IA phosphoinositide 3-kinase inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030398

Resveratrol rescues hyperglycemia-induced endothelial dysfunction via activation of Akt.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030398

Kaempferol induces apoptosis in two different cell lines via Akt inactivation, Bax and SIRT3 activation, and mitochondrial dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030398

Kaempferol induces apoptosis in human lung non-small carcinoma cells accompanied by an induction of antioxidant enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030398

Kaempferol inhibits gastric cancer tumor growth: An in vitro and in vivo study

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030398

Kaempferol suppresses bladder cancer tumor growth by inhibiting cell proliferation and inducing apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030398

The chemopreventive effect of the dietary compound kaempferol on the MCF-7 human breast cancer cell line is dependent on inhibition of glucose cellular uptake.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030398

Curcumin-induced suppression of cell proliferation correlates with down-regulation of cyclin D1 expression and CDK4-mediated retinoblastoma protein phosphorylation

21 January 2018

1 reference

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Curcumin, a multi-functional chemopreventive agent, blocks growth of colon cancer cells by targeting beta-catenin-mediated transactivation and cell-cell adhesion pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030398

Cell cycle inhibition and apoptosis induced by curcumin in Ewing sarcoma cell line SK-NEP-1.

21 January 2018

1 reference

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Curcumin (diferuloylmethane) down-regulates the constitutive activation of nuclear factor-kappa B and IkappaBalpha kinase in human multiple myeloma cells, leading to suppression of proliferation and induction of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030398

Activation of peroxisome proliferator-activated receptor-gamma contributes to the inhibitory effects of curcumin on rat hepatic stellate cell growth

21 January 2018

1 reference

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Curcumin directly inhibits the transport activity of GLUT1

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030398

Larrea tridentata (Creosote bush), an abundant plant of Mexican and US-American deserts and its metabolite nordihydroguaiaretic acid.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030398

Nordihydroguaiaretic acid, an antioxidant, inhibits transforming growth factor-beta activity through the inhibition of Smad signaling pathway.

21 January 2018

1 reference

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Mechanisms of nordihydroguaiaretic acid-induced growth inhibition and apoptosis in human cancer cells

21 January 2018

1 reference

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Nordihydroguaiaretic acid (NDGA) inhibits the IGF-1 and c-erbB2/HER2/neu receptors and suppresses growth in breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030398

Study to evaluate molecular mechanics behind synergistic chemo-preventive effects of curcumin and resveratrol during lung carcinogenesis

21 January 2018

1 reference

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Beneficial effects of combined resveratrol and metformin therapy in treating diet-induced insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030398

Resveratrol directly affects in vitro lipolysis and glucose transport in human fat cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030398

Acute exposure to resveratrol inhibits AMPK activity in human skeletal muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030398

Resveratrol supplementation improves glycemic control in type 2 diabetes mellitus

21 January 2018

1 reference

12 December 2020

Modulation of expression of endothelial nitric oxide synthase by nordihydroguaiaretic acid, a phenolic antioxidant in cultured endothelial cells

1 reference

12 December 2020

Sulphation of resveratrol, a natural compound present in wine, and its inhibition by natural flavonoids

1 reference

12 December 2020

Distribution of the glucose transporters in human brain tumors

1 reference

12 December 2020

Overexpression of Glut-1 glucose transporter in human breast cancer. An immunohistochemical study

1 reference

12 December 2020

A low dose of dietary resveratrol partially mimics caloric restriction and retards aging parameters in mice

1 reference

12 December 2020

Glucose transport: meeting the metabolic demands of cancer, and applications in glioblastoma treatment

1 reference

12 December 2020

Synthesis and anticancer activity of nordihydroguaiaretic acid (NDGA) and analogues.

1 reference

12 December 2020

10.3390/MOLECULES22030398

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DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28272357%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

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5 April 2020

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