TMAO-Protein Preferential Interaction Profile Determines TMAO's Conditional In&#160;Vivo Compatibility (Q39223628)

4 November 2017

TMAO-Protein Preferential Interaction Profile Determines TMAO's Conditional In Vivo Compatibility (English)

1 reference

4 November 2017

Jiang Hong

1

1 reference

PMCID

5103029

4 November 2017

Shangqin Xiong

series ordinal

2

1 reference

PMCID

5103029

4 November 2017

language of work or name

English

0 references

publication date

1 November 2016

1 reference

4 November 2017

10

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inferred from page(s)

published in

Biophysical Journal

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4 November 2017

111

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4 November 2017

1866-1875

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4 November 2017

9

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How osmolytes influence hydrophobic polymer conformations: A unified view from experiment and theory.

4 November 2017

1 reference

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1 reference

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Regulation and aggregation of intrinsically disordered peptides

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1 reference

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Energy landscapes of functional proteins are inherently risky

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Microscopic insights into the protein-stabilizing effect of trimethylamine N-oxide (TMAO)

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1 reference

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1 reference

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Introductory lecture: interpreting and predicting Hofmeister salt ion and solute effects on biopolymer and model processes using the solute partitioning model

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1 reference

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1 reference

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15 June 2018

1 reference

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Entropic stabilization of proteins by TMAO

15 June 2018

1 reference

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Quantifying why urea is a protein denaturant, whereas glycine betaine is a protein stabilizer

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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15 June 2018

1 reference

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Interactions of the osmolyte glycine betaine with molecular surfaces in water: thermodynamics, structural interpretation, and prediction of m-values.

15 June 2018

1 reference

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15 June 2018

1 reference

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1 reference

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Thermodynamic origin of hofmeister ion effects

15 June 2018

1 reference

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15 June 2018

1 reference

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Thermodynamic characterization of the osmolyte effect on protein stability and the effect of GdnHCl on the protein denatured state

15 June 2018

1 reference

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Protein misfolding, functional amyloid, and human disease

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1 reference

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TMAO promotes fibrillization and microtubule assembly activity in the C-terminal repeat region of tau.

15 June 2018

1 reference

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Use of urea and glycine betaine to quantify coupled folding and probe the burial of DNA phosphates in lac repressor-lac operator binding

15 June 2018

1 reference

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Organic osmolytes as compatible, metabolic and counteracting cytoprotectants in high osmolarity and other stresses

15 June 2018

1 reference

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15 June 2018

1 reference

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Counteraction of urea-induced protein denaturation by trimethylamine N-oxide: a chemical chaperone at atomic resolution

15 June 2018

1 reference

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15 June 2018

1 reference

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THERMODYNAMIC ANALYSIS OF MULTICOMPONENT SOLUTIONS.

15 June 2018

1 reference

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Rationalization of the effects of mutations on peptide and protein aggregation rates.

15 June 2018

1 reference

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Measuring the stability of partly folded proteins using TMAO.

15 June 2018

1 reference

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The Cationminus signpi Interaction

15 June 2018

1 reference

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The molecular mechanism of stabilization of proteins by TMAO and its ability to counteract the effects of urea

15 June 2018

1 reference

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Linked folding and anion binding of the Bacillus subtilis ribonuclease P protein

15 June 2018

1 reference

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Osmolyte-driven contraction of a random coil protein

15 June 2018

1 reference

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Trimethylamine-N-oxide counteracts urea effects on rabbit muscle lactate dehydrogenase function: a test of the counteraction hypothesis

15 June 2018

1 reference

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15 June 2018

1 reference

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Denaturant m values and heat capacity changes: relation to changes in accessible surface areas of protein unfolding

15 June 2018

1 reference

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Trimethylamine N-oxide metabolism by abundant marine heterotrophic bacteria.

15 June 2018

1 reference

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17 June 2018

1 reference

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21 August 2018

1 reference

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21 August 2018

1 reference

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Prediction of aggregation-prone regions in structured proteins

21 August 2018

1 reference

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21 August 2018

1 reference

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21 August 2018

1 reference

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21 August 2018

1 reference

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Osmolytes induce structure in an early intermediate on the folding pathway of barstar

21 August 2018

1 reference

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Preferential interactions in aqueous solutions of urea and KCl

21 August 2018

1 reference

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21 August 2018

1 reference

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A bacterial TMAO transporter

21 August 2018

1 reference

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21 August 2018

1 reference

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Trimethylamine-N-oxide-induced folding of alpha-synuclein.

21 August 2018

1 reference

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Natural osmolyte trimethylamine N-oxide corrects assembly defects of mutant branched-chain alpha-ketoacid decarboxylase in maple syrup urine disease

21 August 2018

1 reference

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Manipulating the amyloid-beta aggregation pathway with chemical chaperones.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103029

Control of protein stability and reactions by weakly interacting cosolvents: the simplicity of the complicated.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103029

Analysis of effects of salts and uncharged solutes on protein and nucleic acid equilibria and processes: a practical guide to recognizing and interpreting polyelectrolyte effects, Hofmeister effects, and osmotic effects of salts.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103029

Is a Methyl Group Always Hydrophobic? Hydrophilicity of Trimethylamine-N-oxide, Tetramethyl Urea and Tetramethylammonium Ion

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103029

Life on the edge: a link between gene expression levels and aggregation rates of human proteins

1 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103029

Vapor pressure osmometry studies of osmolyte-protein interactions: implications for the action of osmoprotectants in vivo and for the interpretation of "osmotic stress" experiments in vitro

2 December 2018

1 reference

12 December 2020

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12 December 2020

The role of the concentration scale in the definition of transfer free energies

1 reference

12 December 2020

Methyl groups of trimethylamine N-oxide orient away from hydrophobic interfaces

1 reference

12 December 2020

Forcing thermodynamically unfolded proteins to fold

1 reference

12 December 2020

Natural osmolytes remodel the aggregation pathway of mutant huntingtin exon 1

1 reference

12 December 2020

Why do some organisms use a urea-methylamine mixture as osmolyte? Thermodynamic compensation of urea and trimethylamine N-oxide interactions with protein

1 reference

12 December 2020

10.1016/J.BPJ.2016.09.035

Identifiers

DOI

1 reference

4 November 2017

1 reference

4 November 2017

1 reference

PMCID

5103029