Mutant p53 drives multinucleation and invasion through a process that is suppressed by ANKRD11. (Q39460398)

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14 February 2020

title

Mutant p53 drives multinucleation and invasion through a process that is suppressed by ANKRD11 (English)

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14 February 2020

1

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14 February 2020

Fares Al-Ejeh

3

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14 February 2020

David F. Callen

6

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14 February 2020

Paul M Neilsen

7

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author name string

J Jeffery

2

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14 February 2020

R Kumar

4

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14 February 2020

K K Khanna

5

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language of work or name

English

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publication date

10 October 2011

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14 February 2020

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14 February 2020

volume

31

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issue

23

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page(s)

2836-2848

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A Mutant-p53/Smad complex opposes p63 to empower TGFbeta-induced metastasis

14 February 2020

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A subset of tumor-derived mutant forms of p53 down-regulate p63 and p73 through a direct interaction with the p53 core domain

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Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice

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Small-molecule RETRA suppresses mutant p53-bearing cancer cells through a p73-dependent salvage pathway.

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FBXO31 is the chromosome 16q24.3 senescence gene, a candidate breast tumor suppressor, and a component of an SCF complex

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Cancer. p53, guardian of the genome

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A common gain of function of p53 cancer mutants in inducing genetic instability

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Regulation of the p53 transcriptional activity.

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Deregulated human Cdc14A phosphatase disrupts centrosome separation and chromosome segregation

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Mutant p53 drives invasion by promoting integrin recycling

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A gain of function p53 mutant promotes both genomic instability and cell survival in a novel p53-null mammary epithelial cell model

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Identification of ANKRD11 as a p53 coactivator

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TP53 mutations in human cancers: origins, consequences, and clinical use

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Mutant p53 gain-of-function in cancer

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Nutlin-3a is a potential therapeutic for ewing sarcoma

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Identifiers

DOI

10.1038/ONC.2011.456

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21986947%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

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