Transforming growth factor-β1 induces epithelial-to-mesenchymal transition in human lung cancer cells via PI3K/Akt and MEK/Erk1/2 signaling pathways (Q39516240)

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scientific article published on 29 June 2011

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English	Transforming growth factor-β1 induces epithelial-to-mesenchymal transition in human lung cancer cells via PI3K/Akt and MEK/Erk1/2 signaling pathways	scientific article published on 29 June 2011

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scholarly article

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Europe PubMed Central

PubMed publication ID

12 September 2017

Transforming growth factor-β1 induces epithelial-to-mesenchymal transition in human lung cancer cells via PI3K/Akt and MEK/Erk1/2 signaling pathways (English)

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12 September 2017

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Hong-Tao Zhang

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Xiao-Feng Chen

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12 September 2017

Hui-Jun Zhang

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Hai-Bing Wang

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12 September 2017

Jun Zhu

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Wen-Yong Zhou

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Hui Zhang

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Ming-Chuan Zhao

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Jin-Mei Su

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Wen Gao

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Lei Zhang

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Ke Fei

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12 September 2017

He-Yong Wang

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publication date

29 June 2011

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Molecular Biology Reports

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12 September 2017

39

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4

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3549-3556

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Epithelial-mesenchymal transition in development and cancer: role of phosphatidylinositol 3' kinase/AKT pathways

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https://pubmed.ncbi.nlm.nih.gov/21713404

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Molecular requirements for epithelial-mesenchymal transition during tumor progression

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https://pubmed.ncbi.nlm.nih.gov/21713404

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Diverse cellular and molecular mechanisms contribute to epithelial plasticity and metastasis.

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https://pubmed.ncbi.nlm.nih.gov/21713404

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TGF-beta-induced epithelial to mesenchymal transition

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https://pubmed.ncbi.nlm.nih.gov/21713404

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Reassessing epithelial to mesenchymal transition as a prerequisite for carcinoma invasion and metastasis

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https://pubmed.ncbi.nlm.nih.gov/21713404

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TGF-beta1 induces human alveolar epithelial to mesenchymal cell transition (EMT)

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Dissemination and growth of cancer cells in metastatic sites

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A microenvironmental model of carcinogenesis.

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https://pubmed.ncbi.nlm.nih.gov/21713404

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The epithelial-mesenchymal transition: new insights in signaling, development, and disease

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https://pubmed.ncbi.nlm.nih.gov/21713404

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How cells read TGF-beta signals

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Role of Ras and Mapks in TGFbeta signaling

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https://pubmed.ncbi.nlm.nih.gov/21713404

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Non-Smad TGF-beta signals

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Transforming growth factor beta1 treatment leads to an epithelial-mesenchymal transdifferentiation of pancreatic cancer cells requiring extracellular signal-regulated kinase 2 activation

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Collagen I promotes epithelial-to-mesenchymal transition in lung cancer cells via transforming growth factor-beta signaling

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https://pubmed.ncbi.nlm.nih.gov/21713404

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Smad-dependent and Smad-independent pathways in TGF-beta family signalling

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https://pubmed.ncbi.nlm.nih.gov/21713404

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Dissection of key events in tubular epithelial to myofibroblast transition and its implications in renal interstitial fibrosis

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Cancer metastasis: building a framework

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Hepatocytes convert to a fibroblastoid phenotype through the cooperation of TGF-beta1 and Ha-Ras: steps towards invasiveness.

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Osteopontin stimulates melanoma growth and lung metastasis through NIK/MEKK1-dependent MMP-9 activation pathways.

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Cadherins and catenins in breast cancer

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The war on cancer

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Transforming growth factor-beta regulates tubular epithelial-myofibroblast transdifferentiation in vitro

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https://pubmed.ncbi.nlm.nih.gov/21713404

12 December 2020

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Synergistic effect between EGF and TGF-beta1 in inducing oncogenic properties of intestinal epithelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21713404

12 December 2020

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Epithelial-mesenchymal transition in breast cancer relates to the basal-like phenotype

1 reference

https://pubmed.ncbi.nlm.nih.gov/21713404

12 December 2020

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TGF-beta signaling in tumor suppression and cancer progression

1 reference

https://pubmed.ncbi.nlm.nih.gov/21713404

12 December 2020

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Epithelial-mesenchymal transition in cancer metastasis: mechanisms, markers and strategies to overcome drug resistance in the clinic

1 reference

https://pubmed.ncbi.nlm.nih.gov/21713404

12 December 2020

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Ras and TGF[beta] cooperatively regulate epithelial cell plasticity and metastasis: dissection of Ras signaling pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/21713404

12 December 2020

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Osteopontin: regulation in tumor metastasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21713404

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PI3 kinase/Akt signaling mediates epithelial-mesenchymal transition in hypoxic hepatocellular carcinoma cells

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https://pubmed.ncbi.nlm.nih.gov/21713404

12 December 2020

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Complex networks orchestrate epithelial-mesenchymal transitions

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https://pubmed.ncbi.nlm.nih.gov/21713404

12 December 2020

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Activation of the Erk pathway is required for TGF-beta1-induced EMT in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/21713404

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TGF-beta induced transdifferentiation of mammary epithelial cells to mesenchymal cells: involvement of type I receptors

1 reference

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Clusterin silencing in human lung adenocarcinoma cells induces a mesenchymal-to-epithelial transition through modulating the ERK/Slug pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/21713404

12 December 2020

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Snail is required for transforming growth factor-beta-induced epithelial-mesenchymal transition by activating PI3 kinase/Akt signal pathway

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https://pubmed.ncbi.nlm.nih.gov/21713404

12 December 2020

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Cadherin switching: essential for behavioral but not morphological changes during an epithelium-to-mesenchyme transition.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21713404

12 December 2020

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Epithelial-mesenchymal transitions in development and pathologies

1 reference

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Transforming growth factor-beta and epidermal growth factor synergistically stimulate epithelial to mesenchymal transition (EMT) through a MEK-dependent mechanism in primary cultured pig thyrocytes.

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https://pubmed.ncbi.nlm.nih.gov/21713404

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Transforming growth factor-beta1 induces epithelial-to-mesenchymal transition and apoptosis via a cell cycle-dependent mechanism

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https://pubmed.ncbi.nlm.nih.gov/21713404

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Mammalian cadherins and protocadherins: about cell death, synapses and processing

1 reference

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Epithelial-mesenchymal transitions in tumour progression

1 reference

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Cancer statistics, 2001

1 reference

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12 December 2020

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Identifiers

10.1007/S11033-011-1128-0

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Europe PubMed Central

PubMed publication ID

12 September 2017

release_j6sbmzrobffbdcntdglvdyivfe

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https://api.fatcat.wiki/v0/release/j6sbmzrobffbdcntdglvdyivfe

24 November 2022

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PubMed publication ID

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Europe PubMed Central

PubMed publication ID

12 September 2017

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