Inhibitory effect of unsaturated fatty acids on saturated fatty acid-induced apoptosis in human pancreatic β-cells: activation of caspases and ER stress induction. (Q39521067)

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scientific article published on 15 June 2011

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English	Inhibitory effect of unsaturated fatty acids on saturated fatty acid-induced apoptosis in human pancreatic β-cells: activation of caspases and ER stress induction.	scientific article published on 15 June 2011

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5 February 2020

Inhibitory effect of unsaturated fatty acids on saturated fatty acid-induced apoptosis in human pancreatic β-cells: activation of caspases and ER stress induction (English)

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5 February 2020

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Vlasta Němcová-Fürstová

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5 February 2020

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Roger F L James

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15 June 2011

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Cellular Physiology and Biochemistry

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525-538

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5 February 2020

Reduced beta-cell mass and expression of oxidative stress-related DNA damage in the islet of Japanese Type II diabetic patients.

1 reference

https://api.crossref.org/works/10.1159%2F000329954

21 January 2018

Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes

1 reference

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21 January 2018

Beta-cell failure as a complication of diabetes

1 reference

https://api.crossref.org/works/10.1159%2F000329954

21 January 2018

The cytoprotective actions of long-chain mono-unsaturated fatty acids in pancreatic beta-cells

1 reference

https://api.crossref.org/works/10.1159%2F000329954

21 January 2018

Distinct effects of saturated and monounsaturated fatty acids on beta-cell turnover and function

1 reference

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21 January 2018

Different role of saturated and unsaturated fatty acids in beta-cell apoptosis

1 reference

https://api.crossref.org/works/10.1159%2F000329954

21 January 2018

Monounsaturated fatty acids prevent the deleterious effects of palmitate and high glucose on human pancreatic beta-cell turnover and function

1 reference

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21 January 2018

Comparison of the effect of individual saturated and unsaturated fatty acids on cell growth and death induction in the human pancreatic beta-cell line NES2Y.

1 reference

https://api.crossref.org/works/10.1159%2F000329954

21 January 2018

Protein kinase C delta activation and translocation to the nucleus are required for fatty acid-induced apoptosis of insulin-secreting cells

1 reference

https://api.crossref.org/works/10.1159%2F000329954

21 January 2018

Saturated fatty acids synergize with elevated glucose to cause pancreatic beta-cell death

1 reference

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21 January 2018

Adiponectin counteracts cytokine- and fatty acid-induced apoptosis in the pancreatic beta-cell line INS-1.

1 reference

https://api.crossref.org/works/10.1159%2F000329954

21 January 2018

Sequential activation of caspases and synergistic beta-cell cytotoxicity by palmitate and anti-Fas antibodies.

1 reference

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21 January 2018

Involvement of Ca2+-mediated apoptotic signals in palmitate-induced MIN6N8a beta cell death

1 reference

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21 January 2018

Structural requirements for the cytoprotective actions of mono-unsaturated fatty acids in the pancreatic beta-cell line, BRIN-BD11

1 reference

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21 January 2018

Pancreatic islets from type 2 diabetic patients have functional defects and increased apoptosis that are ameliorated by metformin.

1 reference

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21 January 2018

Mitochondrial dysfunction is involved in apoptosis induced by serum withdrawal and fatty acids in the beta-cell line INS-1.

1 reference

https://api.crossref.org/works/10.1159%2F000329954

21 January 2018

Protein kinase B/Akt prevents fatty acid-induced apoptosis in pancreatic beta-cells (INS-1).

1 reference

https://api.crossref.org/works/10.1159%2F000329954

21 January 2018

Alterations in microRNA expression contribute to fatty acid-induced pancreatic beta-cell dysfunction

1 reference

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21 January 2018

The PIDDosome, a protein complex implicated in activation of caspase-2 in response to genotoxic stress

1 reference

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21 January 2018

Inverse relationship between cytotoxicity of free fatty acids in pancreatic islet cells and cellular triglyceride accumulation.

1 reference

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21 January 2018

Initiation and execution of lipotoxic ER stress in pancreatic beta-cells

1 reference

https://api.crossref.org/works/10.1159%2F000329954

21 January 2018

Fatty acid protection from palmitic acid-induced apoptosis is lost following PI3-kinase inhibition

1 reference

https://api.crossref.org/works/10.1159%2F000329954

21 January 2018

Mono-unsaturated fatty acids protect against beta-cell apoptosis induced by saturated fatty acids, serum withdrawal or cytokine exposure

1 reference

https://api.crossref.org/works/10.1159%2F000329954

21 January 2018

Differential protective effects of palmitoleic acid and cAMP on caspase activation and cell viability in pancreatic beta-cells exposed to palmitate

1 reference

https://api.crossref.org/works/10.1159%2F000329954

21 January 2018

Chronic palmitate but not oleate exposure induces endoplasmic reticulum stress, which may contribute to INS-1 pancreatic beta-cell apoptosis

1 reference

https://api.crossref.org/works/10.1159%2F000329954

21 January 2018

Endoplasmic reticulum stress contributes to beta cell apoptosis in type 2 diabetes

1 reference

https://api.crossref.org/works/10.1159%2F000329954

21 January 2018

Differential regulation of the endoplasmic reticulum stress response in pancreatic beta-cells exposed to long-chain saturated and monounsaturated fatty acids

1 reference

https://api.crossref.org/works/10.1159%2F000329954

21 January 2018

Differential regulation of the ER stress response by long-chain fatty acids in the pancreatic beta-cell

1 reference

https://api.crossref.org/works/10.1159%2F000329954

21 January 2018

Impaired expression of transcription factor IUF1 in a pancreatic beta-cell line derived from a patient with persistent hyperinsulinaemic hypoglycaemia of infancy (nesidioblastosis).

1 reference

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21 January 2018

Engineering a glucose-responsive human insulin-secreting cell line from islets of Langerhans isolated from a patient with persistent hyperinsulinemic hypoglycemia of infancy

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21 January 2018

Additive stimulatory effect of extracellular calcium and potassium on non-transferrin ferric iron uptake by HeLa and K562 cells.

1 reference

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21 January 2018

Iron deprivation induces apoptosis via mitochondrial changes related to Bax translocation.

1 reference

https://api.crossref.org/works/10.1159%2F000329954

21 January 2018

Quantitation of mitochondrial alterations associated with apoptosis

1 reference

https://api.crossref.org/works/10.1159%2F000329954

21 January 2018

Measurement of protein using bicinchoninic acid

1 reference

https://api.crossref.org/works/10.1159%2F000329954

21 January 2018

Cell death induced by novel fluorinated taxanes in drug-sensitive and drug-resistant cancer cells.

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21 January 2018

Resveratrol-induced cytotoxicity in human Burkitt's lymphoma cells is coupled to the unfolded protein response

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21 January 2018

Differing expression of genes involved in non-transferrin iron transport across plasma membrane in various cell types under iron deficiency and excess

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21 January 2018

Quantitative determination of plasma c8-c26 total fatty acids for the biochemical diagnosis of nutritional and metabolic disorders

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21 January 2018

WAF1, a potential mediator of p53 tumor suppression

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21 January 2018

Autoproteolysis of PIDD marks the bifurcation between pro-death caspase-2 and pro-survival NF-kappaB pathway

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21 January 2018

Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response

1 reference

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21 January 2018

Roles of CHOP/GADD153 in endoplasmic reticulum stress

1 reference

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21 January 2018

The role for endoplasmic reticulum stress in diabetes mellitus

1 reference

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21 January 2018

Mechanisms involved in the cytotoxic and cytoprotective actions of saturated versus monounsaturated long-chain fatty acids in pancreatic beta-cells

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21 January 2018

Ex vivo transcriptional profiling of human pancreatic islets following chronic exposure to monounsaturated fatty acids

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21 January 2018

Identification and classification of p53-regulated genes

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21 January 2018

Caspase-2 activation in the absence of PIDDosome formation

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21 January 2018

DISC-mediated activation of caspase-2 in DNA damage-induced apoptosis

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Glucose induces beta-cell apoptosis via upregulation of the Fas receptor in human islets

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FLIP switches Fas-mediated glucose signaling in human pancreatic beta cells from apoptosis to cell replication

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21 January 2018

Deletion of Fas in the pancreatic beta-cells leads to enhanced insulin secretion

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21 January 2018

RyR2 and calpain-10 delineate a novel apoptosis pathway in pancreatic islets

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21 January 2018

Enhanced signaling downstream of ribonucleic Acid-activated protein kinase-like endoplasmic reticulum kinase potentiates lipotoxic endoplasmic reticulum stress in human islets.

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Glucagon-like peptide-1 agonists protect pancreatic beta-cells from lipotoxic endoplasmic reticulum stress through upregulation of BiP and JunB.

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21 January 2018

Increased fatty acid desaturation and enhanced expression of stearoyl coenzyme A desaturase protects pancreatic beta-cells from lipoapoptosis.

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Caspase-12 and ER-stress-mediated apoptosis: the story so far.

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Inflammatory caspases and inflammasomes: master switches of inflammation

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Involvement of caspase-2 and caspase-9 in endoplasmic reticulum stress-induced apoptosis: a role for the IAPs.

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21 January 2018

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