Upregulation of ABCG2 by romidepsin via the aryl hydrocarbon receptor pathway. (Q39584939)

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23 January 2020

title

Upregulation of ABCG2 by romidepsin via the aryl hydrocarbon receptor pathway (English)

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23 January 2020

1

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23 January 2020

Rob Robey

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2

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23 January 2020

5

Susan E Bates

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23 January 2020

author name string

Zhirong Zhan

series ordinal

3

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23 January 2020

Lois Bangiolo

series ordinal

4

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23 January 2020

publication date

25 February 2011

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Molecular Cancer Research

23 January 2020

published in

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23 January 2020

volume

9

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23 January 2020

issue

4

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23 January 2020

page(s)

516-527

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Increased MDR1 expression in normal and malignant peripheral blood mononuclear cells obtained from patients receiving depsipeptide (FR901228, FK228, NSC630176).

23 January 2020

cites work

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Aberrant promoter methylation of the ABCG2 gene in renal carcinoma

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Inhibition of histone deacetylase 6 acetylates and disrupts the chaperone function of heat shock protein 90: a novel basis for antileukemia activity of histone deacetylase inhibitors.

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Resveratrol inhibits transcription of CYP1A1 in vitro by preventing activation of the aryl hydrocarbon receptor

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Modulation of p53, ErbB1, ErbB2, and Raf-1 expression in lung cancer cells by depsipeptide FR901228

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HSP90 and the chaperoning of cancer

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Regulation of signaling protein function and trafficking by the hsp90/hsp70-based chaperone machinery

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Reduction of androgen receptor expression by benzo[alpha]pyrene and 7,8-dihydro-9,10-epoxy-7,8,9,10-tetrahydrobenzo[alpha]pyrene in human lung cells.

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Pheophorbide a is a specific probe for ABCG2 function and inhibition.

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Activity of suberoylanilide hydroxamic Acid against human breast cancer cells with amplification of her-2.

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Overexpression of the BCRP/MXR/ABCP gene in a topotecan-selected ovarian tumor cell line.

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Ligand binding and activation of the Ah receptor

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A human placenta-specific ATP-binding cassette gene (ABCP) on chromosome 4q22 that is involved in multidrug resistance

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In vivo cross-linking and immunoprecipitation for studying dynamic Protein:DNA associations in a chromatin environment

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Aryl hydrocarbon receptor expression is associated with a family history of upper gastrointestinal tract cancer in a high-risk population exposed to aromatic hydrocarbons

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Aryl hydrocarbon receptor is a transcriptional activator of the human breast cancer resistance protein (BCRP/ABCG2).

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HDAC6 regulates Hsp90 acetylation and chaperone-dependent activation of glucocorticoid receptor

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Molecular cloning of cDNAs which are highly overexpressed in mitoxantrone-resistant cells: demonstration of homology to ABC transport genes

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A multidrug resistance transporter from human MCF-7 breast cancer cells

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12 December 2020

Overexpression of the ATP-binding cassette half-transporter, ABCG2 (Mxr/BCrp/ABCP1), in flavopiridol-resistant human breast cancer cells

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12 December 2020

Histone deacetylase inhibitor LAQ824 down-regulates Her-2 and sensitizes human breast cancer cells to trastuzumab, taxotere, gemcitabine, and epothilone B

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12 December 2020

Hydroxamic acid analogue histone deacetylase inhibitors attenuate estrogen receptor-alpha levels and transcriptional activity: a result of hyperacetylation and inhibition of chaperone function of heat shock protein 90.

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12 December 2020

The expression of a small fraction of cellular genes is changed in response to histone hyperacetylation.

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12 December 2020

Human class I histone deacetylase complexes show enhanced catalytic activity in the presence of ATP and co-immunoprecipitate with the ATP-dependent chaperone protein Hsp70

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12 December 2020

Role of heat shock protein 90 dissociation in mediating agonist-induced activation of the aryl hydrocarbon receptor

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12 December 2020

Identification of patterns in biological sequences at the ALGGEN server: PROMO and MALGEN.

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12 December 2020

Identification of kaempferol as an inhibitor of cigarette smoke-induced activation of the aryl hydrocarbon receptor and cell transformation

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12 December 2020

siRNA Selection Server: an automated siRNA oligonucleotide prediction server

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Aryl hydrocarbon receptor activation and overexpression upregulated fibroblast growth factor-9 in human lung adenocarcinomas.

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Hsp70 and Hsp90--a relay team for protein folding

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12 December 2020

FK228 inhibits Hsp90 chaperone function in K562 cells via hyperacetylation of Hsp70

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12 December 2020

Histone deacetylase inhibitors induce a very broad, pleiotropic anticancer drug resistance phenotype in acute myeloid leukemia cells by modulation of multiple ABC transporter genes

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12 December 2020

Disruption of the Raf-1-Hsp90 Molecular Complex Results in Destabilization of Raf-1 and Loss of Raf-1-Ras Association

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12 December 2020

Histone deacetylase inhibitor LAQ824 both lowers expression and promotes proteasomal degradation of Bcr-Abl and induces apoptosis of imatinib mesylate-sensitive or -refractory chronic myelogenous leukemia-blast crisis cells.

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12 December 2020

Prolonged depletion of AH receptor without alteration of receptor mRNA levels after treatment of cells in culture with 2,3,7,8-tetrachlorodibenzo-p-dioxin

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12 December 2020

Hsp90 inhibitors as novel cancer chemotherapeutic agents

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12 December 2020

DNA binding and protein interactions of the AHR/ARNT heterodimer that facilitate gene activation

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12 December 2020

Resveratrol inhibits dioxin-induced expression of human CYP1A1 and CYP1B1 by inhibiting recruitment of the aryl hydrocarbon receptor complex and RNA polymerase II to the regulatory regions of the corresponding genes

1 reference

12 December 2020

ABCG2: a perspective.

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12 December 2020

The drug salicylamide is an antagonist of the aryl hydrocarbon receptor that inhibits signal transduction induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin

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12 December 2020

Overexpression of wild-type breast cancer resistance protein mediates methotrexate resistance.

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12 December 2020

Up-regulation of MDR1 and induction of doxorubicin resistance by histone deacetylase inhibitor depsipeptide (FK228) and ATRA in acute promyelocytic leukemia cells

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12 December 2020

Akt forms an intracellular complex with heat shock protein 90 (Hsp90) and Cdc37 and is destabilized by inhibitors of Hsp90 function

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12 December 2020

Histone-deacetylase inhibitors: novel drugs for the treatment of cancer

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12 December 2020

FK228 (depsipeptide) as a natural prodrug that inhibits class I histone deacetylases

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12 December 2020

Modulation of Akt kinase activity by binding to Hsp90

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12 December 2020

Regulation of constitutive and inducible AHR signaling: complex interactions involving the AHR repressor

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12 December 2020

Histone modifications at the ABCG2 promoter following treatment with histone deacetylase inhibitor mirror those in multidrug-resistant cells

1 reference

12 December 2020

10.1158/1541-7786.MCR-10-0270

Identifiers

DOI

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23 January 2020

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