Calcium/calmodulin-dependent kinase IV controls glucose-induced Irs2 expression in mouse beta cells via activation of cAMP response element-binding protein. (Q39596238)

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scientific article published on 8 February 2011

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English	Calcium/calmodulin-dependent kinase IV controls glucose-induced Irs2 expression in mouse beta cells via activation of cAMP response element-binding protein.	scientific article published on 8 February 2011

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21 January 2020

Calcium/calmodulin-dependent kinase IV controls glucose-induced Irs2 expression in mouse beta cells via activation of cAMP response element-binding protein (English)

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21 January 2020

Shanta J. Persaud

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21 January 2020

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21 January 2020

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B Liu

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21 January 2020

H Barbosa Sampaio

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21 January 2020

D S Muller

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21 January 2020

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8 February 2011

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21 January 2020

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21 January 2020

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21 January 2020

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21 January 2020

1109-1120

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21 January 2020

https://scigraph.springernature.com/pub.10.1007/s00125-011-2050-7

0 references

Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes

1 reference

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Mechanisms of disease:Molecular and metabolic mechanisms of insulin resistance and beta-cell failure in type 2 diabetes

1 reference

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21 January 2018

An examination of beta-cell function measures and their potential use for estimating beta-cell mass.

1 reference

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21 January 2018

Prevention of type 2 diabetes: insulin resistance and beta-cell function

1 reference

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Pancreatic B-cell defects in gestational diabetes: implications for the pathogenesis and prevention of type 2 diabetes

1 reference

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Increased beta-cell apoptosis prevents adaptive increase in beta-cell mass in mouse model of type 2 diabetes: evidence for role of islet amyloid formation rather than direct action of amyloid

1 reference

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21 January 2018

Dietary-fat-induced obesity in mice results in beta cell hyperplasia but not increased insulin release: evidence for specificity of impaired beta cell adaptation

1 reference

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21 January 2018

Adaptation of islets of Langerhans to pregnancy: increased islet cell proliferation and insulin secretion correlates with the onset of placental lactogen secretion

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21 January 2018

Specific and Combined Effects of Insulin and Glucose on Functional Pancreatic β-Cell Mass in Vivo in Adult Rats

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21 January 2018

Autocrine anti-apoptotic and proliferative effects of insulin in pancreatic beta-cells

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2050-7

21 January 2018

Autocrine insulin action activates Akt and increases survival of isolated human islets.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2050-7

21 January 2018

The metabolisable hexoses D-glucose and D-mannose enhance the expression of IRS-2 but not of IRS-1 in pancreatic beta-cells

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2050-7

21 January 2018

Specific regulation of IRS-2 expression by glucose in rat primary pancreatic islet beta-cells

1 reference

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21 January 2018

Disruption of insulin receptor substrate 2 causes type 2 diabetes because of liver insulin resistance and lack of compensatory beta-cell hyperplasia.

1 reference

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21 January 2018

Disruption of IRS-2 causes type 2 diabetes in mice

1 reference

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21 January 2018

Upregulation of insulin receptor substrate-2 in pancreatic beta cells prevents diabetes

1 reference

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21 January 2018

Exendin-4 uses Irs2 signaling to mediate pancreatic beta cell growth and function

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2050-7

21 January 2018

Calcium regulation of dendritic growth via CaM kinase IV and CREB-mediated transcription.

1 reference

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21 January 2018

The role of calcium/calmodulin-dependent protein kinase cascade in glucose upregulation of insulin gene expression

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2050-7

21 January 2018

Activating transcription factor-2 is a positive regulator in CaM kinase IV-induced human insulin gene expression

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2050-7

21 January 2018

cAMP promotes pancreatic beta-cell survival via CREB-mediated induction of IRS2.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2050-7

21 January 2018

Islet transplantation outcomes in mice are better with fresh islets and exendin-4 treatment

1 reference

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21 January 2018

Anti-apoptotic effects of arachidonic acid and prostaglandin E2 in pancreatic beta-cells.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2050-7

21 January 2018

Identification of insulin signaling elements in human beta-cells: autocrine regulation of insulin gene expression.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2050-7

21 January 2018

Regulation of activating transcription factor-1 and the cAMP response element-binding protein by Ca2+/calmodulin-dependent protein kinases type I, II, and IV.

1 reference

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21 January 2018

Failure of Ca2+-activated, CREB-dependent transcription in astrocytes

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21 January 2018

Ca2+/calmodulin-dependent protein kinases II and IV both promote survival but differ in their effects on axon growth in spiral ganglion neurons.

1 reference

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21 January 2018

Calcium promotes cell survival through CaM-K kinase activation of the protein-kinase-B pathway

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2050-7

21 January 2018

Calcium/calmodulin-dependent protein kinase type IV (CaMKIV) inhibits apoptosis induced by potassium deprivation in cerebellar granule neurons

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2050-7

21 January 2018

Translocation of calmodulin to the nucleus supports CREB phosphorylation in hippocampal neurons

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2050-7

21 January 2018

Glucose controls CREB activity in islet cells via regulated phosphorylation of TORC2

1 reference

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21 January 2018

Blood glucose levels regulate pancreatic beta-cell proliferation during experimentally-induced and spontaneous autoimmune diabetes in mice

1 reference

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21 January 2018

Glucose promotes survival of rat pancreatic beta cells by activating synthesis of proteins which suppress a constitutive apoptotic program

1 reference

https://api.crossref.org/works/10.1007%2FS00125-011-2050-7

21 January 2018

Interplay of Ca2+ and cAMP signaling in the insulin-secreting MIN6 beta-cell line

1 reference

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21 January 2018

Pancreatic beta cell line MIN6 exhibits characteristics of glucose metabolism and glucose-stimulated insulin secretion similar to those of normal islets

1 reference

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21 January 2018

Calcium/calmodulin-dependent protein kinase type IV is a target gene of the Wnt/beta-catenin signaling pathway.

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The Wnt signaling pathway effector TCF7L2 and type 2 diabetes mellitus

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The WNT signalling pathway and diabetes mellitus

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Glucagon-like peptide-1 activation of TCF7L2-dependent Wnt signaling enhances pancreatic beta cell proliferation

1 reference

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TCF7L2 controls insulin gene expression and insulin secretion in mature pancreatic beta-cells

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21 January 2018

Compensatory Growth of Pancreatic -Cells in Adult Rats After Short-Term Glucose Infusion

1 reference

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Dynamics of insulin secretion in obesity and diabetes

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Regulation of pancreatic beta-cell mass in vivo

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Adaptation of beta-cell mass to substrate oversupply: enhanced function with normal gene expression

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Impaired synaptic plasticity and cAMP response element-binding protein activation in Ca2+/calmodulin-dependent protein kinase type IV/Gr-deficient mice

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Beta cell failure: causes and consequences

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Characterization of Ca2+/calmodulin-dependent protein kinase IV. Role in transcriptional regulation.

1 reference

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Structural and functional abnormalities in the islets isolated from type 2 diabetic subjects

1 reference

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inferred from PubMed ID database lookup

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