Proteasome inhibitor MG-132 mediated expression of p27Kip1 via S-phase kinase protein 2 degradation induces cell cycle coupled apoptosis in primary effusion lymphoma cells. (Q39832776)

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English	Proteasome inhibitor MG-132 mediated expression of p27Kip1 via S-phase kinase protein 2 degradation induces cell cycle coupled apoptosis in primary effusion lymphoma cells.	scientific article

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1 February 2020

Proteasome inhibitor MG-132 mediated expression of p27Kip1 via S-phase kinase protein 2 degradation induces cell cycle coupled apoptosis in primary effusion lymphoma cells (English)

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1 February 2020

apoptotic process

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primary effusion lymphoma

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based on heuristic

inferred from title

9

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1 February 2020

author name string

Azhar R Hussain

1

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1 February 2020

Maqbool Ahmed

2

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1 February 2020

Saeeda O Ahmed

3

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1 February 2020

Sara Al-Thari

4

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1 February 2020

Asma S Khan

5

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1 February 2020

Shirin Razack

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1 February 2020

Leonidas C Platanias

7

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1 February 2020

Khawla S Al-Kuraya

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publication date

1 July 2009

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Leukemia & Lymphoma

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50

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1204-1213

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7

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1 February 2020

Primary effusion lymphoma (PEL) in HIV-negative patients--a distinct clinical entity

1 reference

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21 January 2018

The ubiquitin-proteasome proteolytic pathway

1 reference

https://api.crossref.org/works/10.1080%2F10428190902951799

21 January 2018

Activity-based ubiquitin-specific protease (USP) profiling of virus-infected and malignant human cells

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The proteasome: a worthwhile target for the treatment of solid tumours?

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https://api.crossref.org/works/10.1080%2F10428190902951799

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p45SKP2 promotes p27Kip1 degradation and induces S phase in quiescent cells

1 reference

https://api.crossref.org/works/10.1080%2F10428190902951799

21 January 2018

S-phase kinase protein 2 is an attractive therapeutic target in a subset of diffuse large B-cell lymphoma.

1 reference

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21 January 2018

Bortezomib (Velcade) induces p27Kip1 expression through S-phase kinase protein 2 degradation in colorectal cancer.

1 reference

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Oncogenic role of the ubiquitin ligase subunit Skp2 in human breast cancer

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The apoptogenic response of human myeloid leukaemia cell lines and of normal and malignant haematopoietic progenitor cells to the proteasome inhibitor PSI.

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Proteasome inhibition in cancer: development of PS-341.

1 reference

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Apoptosis in brain-specific autoimmune disease

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Apoptosis control in syncytia induced by the HIV type 1-envelope glycoprotein complex: role of mitochondria and caspases.

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Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

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The biochemistry of apoptosis

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Sanguinarine-dependent induction of apoptosis in primary effusion lymphoma cells.

1 reference

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Curcumin induces apoptosis via inhibition of PI3'-kinase/AKT pathway in acute T cell leukemias

1 reference

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Curcumin suppresses growth and induces apoptosis in primary effusion lymphoma.

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Role of phosphatidylinositol 3'-kinase/AKT pathway in diffuse large B-cell lymphoma survival

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Differentiation stage-specific activation of p38 mitogen-activated protein kinase isoforms in primary human erythroid cells

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21 January 2018

Curcumin suppresses constitutive activation of nuclear factor-kappa B and requires functional Bax to induce apoptosis in Burkitt's lymphoma cell lines.

1 reference

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21 January 2018

Inhibition of phosphatidylinositol 3'-kinase/AKT signaling promotes apoptosis of primary effusion lymphoma cells.

1 reference

https://api.crossref.org/works/10.1080%2F10428190902951799

21 January 2018

Inhibition of phosphatidylinositol 3'-kinase induces preferentially killing of PTEN-null T leukemias through AKT pathway.

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21 January 2018

Cyclin is degraded by the ubiquitin pathway

1 reference

https://api.crossref.org/works/10.1080%2F10428190902951799

21 January 2018

Cleavage of p21Cip1/Waf1 and p27Kip1 mediates apoptosis in endothelial cells through activation of Cdk2: role of a caspase cascade

1 reference

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21 January 2018

N-Terminal ubiquitination of extracellular signal-regulated kinase 3 and p21 directs their degradation by the proteasome

1 reference

https://api.crossref.org/works/10.1080%2F10428190902951799

21 January 2018

Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27

1 reference

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21 January 2018

Ciglitazone-induced cellular anti-proliferation increases p27kip1 protein levels through both increased transcriptional activity and inhibition of proteasome degradation.

1 reference

https://api.crossref.org/works/10.1080%2F10428190902951799

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Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

1 reference

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Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

1 reference

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Bid-induced conformational change of Bax is responsible for mitochondrial cytochrome c release during apoptosis

1 reference

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Ubiquitin ligases: cell-cycle control and cancer

1 reference

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Deregulated degradation of the cdk inhibitor p27 and malignant transformation.

1 reference

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A novel target gene, SKP2, within the 5p13 amplicon that is frequently detected in small cell lung cancers.

1 reference

https://api.crossref.org/works/10.1080%2F10428190902951799

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Bax-induced caspase activation and apoptosis via cytochrome c release from mitochondria is inhibitable by Bcl-xL.

1 reference

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Bax directly induces release of cytochrome c from isolated mitochondria

1 reference

https://api.crossref.org/works/10.1080%2F10428190902951799

21 January 2018

Cytochrome c release occurs via Ca2+-dependent and Ca2+-independent mechanisms that are regulated by Bax.

1 reference

https://api.crossref.org/works/10.1080%2F10428190902951799

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An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9

1 reference

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21 January 2018

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