Activation of p53 by MDM2 antagonists has differential apoptotic effects on Epstein-Barr virus (EBV)-positive and EBV-negative Burkitt's lymphoma cells (Q39855621)

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English	Activation of p53 by MDM2 antagonists has differential apoptotic effects on Epstein-Barr virus (EBV)-positive and EBV-negative Burkitt's lymphoma cells	scientific article

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scholarly article

1 reference

Europe PubMed Central

15 September 2017

Activation of p53 by MDM2 antagonists has differential apoptotic effects on Epstein-Barr virus (EBV)-positive and EBV-negative Burkitt's lymphoma cells (English)

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Europe PubMed Central

15 September 2017

apoptotic process

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Burkitt lymphoma

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Epstein–Barr virus

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object named as

J Wiels

6

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author name string

B Renouf

1

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Europe PubMed Central

15 September 2017

E Hollville

2

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Europe PubMed Central

15 September 2017

A Pujals

3

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Europe PubMed Central

15 September 2017

C Tétaud

4

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Europe PubMed Central

15 September 2017

J Garibal

5

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Europe PubMed Central

15 September 2017

publication date

7 May 2009

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Europe PubMed Central

15 September 2017

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Europe PubMed Central

15 September 2017

23

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Europe PubMed Central

15 September 2017

1557-1563

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Europe PubMed Central

15 September 2017

9

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Europe PubMed Central

15 September 2017

https://scigraph.springernature.com/pub.10.1038/leu.2009.92

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The p53 pathway: positive and negative feedback loops

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https://api.crossref.org/works/10.1038%2FLEU.2009.92

21 January 2018

Surfing the p53 network

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https://api.crossref.org/works/10.1038%2FLEU.2009.92

21 January 2018

Live or let die: the cell's response to p53

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https://api.crossref.org/works/10.1038%2FLEU.2009.92

21 January 2018

MDM2 is a central node in the p53 pathway: 12 years and counting

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https://api.crossref.org/works/10.1038%2FLEU.2009.92

21 January 2018

Amplification of a gene encoding a p53-associated protein in human sarcomas

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2009.92

21 January 2018

A single nucleotide polymorphism in the MDM2 promoter attenuates the p53 tumor suppressor pathway and accelerates tumor formation in humans

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2009.92

21 January 2018

Overexpression of MDM2, due to enhanced translation, results in inactivation of wild-type p53 in Burkitt's lymphoma cells.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2009.92

21 January 2018

MDM2 oncogene as a novel target for human cancer therapy

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https://api.crossref.org/works/10.1038%2FLEU.2009.92

21 January 2018

Small molecule inhibitors of HDM2 ubiquitin ligase activity stabilize and activate p53 in cells

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https://api.crossref.org/works/10.1038%2FLEU.2009.92

21 January 2018

In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2009.92

21 January 2018

Reactivation of the p53 pathway as a treatment modality for KSHV-induced lymphomas.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2009.92

21 January 2018

Nongenotoxic activation of the p53 pathway as a therapeutic strategy for multiple myeloma

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2009.92

21 January 2018

Mouse double minute antagonist Nutlin-3a enhances chemotherapy-induced apoptosis in cancer cells with mutant p53 by activating E2F1.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2009.92

21 January 2018

MDM2 inhibition sensitizes neuroblastoma to chemotherapy-induced apoptotic cell death

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2009.92

21 January 2018

Radiosensitization of lung cancer by nutlin, an inhibitor of murine double minute 2.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2009.92

21 January 2018

MDM2 antagonists activate p53 and synergize with genotoxic drugs in B-cell chronic lymphocytic leukemia cells.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2009.92

21 January 2018

Inhibition of p53-murine double minute 2 interaction by nutlin-3A stabilizes p53 and induces cell cycle arrest and apoptosis in Hodgkin lymphoma

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2009.92

21 January 2018

Functional integrity of the p53-mediated apoptotic pathway induced by the nongenotoxic agent nutlin-3 in B-cell chronic lymphocytic leukemia (B-CLL).

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2009.92

21 January 2018

p53 mutations in human lymphoid malignancies: association with Burkitt lymphoma and chronic lymphocytic leukemia

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https://api.crossref.org/works/10.1038%2FLEU.2009.92

21 January 2018

Inactivation of the ARF-MDM-2-p53 pathway in sporadic Burkitt's lymphoma in children.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2009.92

21 January 2018

Role of genetic and epigenetic changes in Burkitt lymphoma

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2009.92

21 January 2018

Epstein-Barr virus and cancer

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2009.92

21 January 2018

Three restricted forms of Epstein-Barr virus latency counteracting apoptosis in c-myc-expressing Burkitt lymphoma cells.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2009.92

21 January 2018

Epstein–Barr virus can inhibit genotoxin-induced G1 arrest downstream of p53 by preventing the inactivation of CDK2

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2009.92

21 January 2018

Epstein-Barr virus suppresses a G(2)/M checkpoint activated by genotoxins

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2009.92

21 January 2018

Correlation between immunoglobulin light chain expression and variant translocation in Burkitt's lymphoma

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2009.92

21 January 2018

Identification and classification of p53-regulated genes

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2009.92

21 January 2018

Cell survival, cell death and cell cycle pathways are interconnected: implications for cancer therapy

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2009.92

21 January 2018

MDM2 inhibitors for cancer therapy

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2009.92

21 January 2018

Functional p53 signaling in Kaposi's sarcoma-associated herpesvirus lymphomas: implications for therapy.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2009.92

21 January 2018

HDM2 antagonist Nutlin-3 disrupts p73-HDM2 binding and enhances p73 function.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2009.92

21 January 2018

MDM2 antagonist nutlin-3 displays antiproliferative and proapoptotic activity in mantle cell lymphoma.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2009.92

21 January 2018

Spectrum of Kaposi's sarcoma-associated herpesvirus, or human herpesvirus 8, diseases

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2009.92

21 January 2018

Nutlin-3 protects kidney cells during cisplatin therapy by suppressing Bax/Bak activation

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2009.92

21 January 2018

Nongenotoxic p53 activation protects cells against S-phase-specific chemotherapy

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2009.92

21 January 2018

Epstein-barr virus nuclear antigen 2 retards cell growth, induces p21(WAF1) expression, and modulates p53 activity post-translationally.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2009.92

21 January 2018

Epstein-Barr virus selectively deregulates DNA damage responses in normal B cells but has no detectable effect on regulation of the tumor suppressor p53.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2009.92

21 January 2018

Apoptosis of tumoral and nontumoral lymphoid cells is induced by both mdm2 and p53 antisense oligodeoxynucleotides

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2009.92

21 January 2018

p14ARF homozygous deletion or MDM2 overexpression in Burkitt lymphoma lines carrying wild type p53

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2009.92

7 January 2021

based on heuristic

inferred from DOI database lookup

Differences in B cell growth phenotype reflect novel patterns of Epstein-Barr virus latent gene expression in Burkitt's lymphoma cells

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https://api.crossref.org/works/10.1038%2FLEU.2009.92

7 January 2021

based on heuristic

inferred from DOI database lookup

Activation of p53 by MDM2 antagonists can protect proliferating cells from mitotic inhibitors

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2009.92

7 January 2021

based on heuristic

inferred from DOI database lookup

Involvement of cyclin-dependent kinases in doxorubicin-induced apoptosis in human tumor cells

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2009.92

7 January 2021

based on heuristic

inferred from DOI database lookup

DNA damage in human B cells can induce apoptosis, proceeding from G1/S when p53 is transactivation competent and G2/M when it is transactivation defective.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2009.92

7 January 2021

based on heuristic

inferred from DOI database lookup

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10.1038/LEU.2009.92

1 reference

Europe PubMed Central

15 September 2017

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release_3fzeyymgenextmgcadqbt2nbwe

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https://api.fatcat.wiki/v0/release/3fzeyymgenextmgcadqbt2nbwe

24 November 2022

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mapped directly with Wikidata item

1 reference

Europe PubMed Central

15 September 2017

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