Upregulation of DR5 by proteasome inhibitors potently sensitizes glioma cells to TRAIL-induced apoptosis. (Q40002391)

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4 January 2020

title

Upregulation of DR5 by proteasome inhibitors potently sensitizes glioma cells to TRAIL-induced apoptosis (English)

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4 January 2020

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4

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4 January 2020

author name string

Holger Hetschko

1

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4 January 2020

Valerie Voss

2

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4 January 2020

Volker Seifert

3

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4 January 2020

Donat Kögel

5

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4 January 2020

language of work or name

English

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publication date

13 March 2008

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4 January 2020

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4 January 2020

volume

275

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4 January 2020

issue

8

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4 January 2020

page(s)

1925-1936

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The WHO classification of tumors of the nervous system

4 January 2020

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TRAIL sensitizes for ionizing irradiation-induced apoptosis through an entirely Bax-dependent mitochondrial cell death pathway

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Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules

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Pharmacological inhibition of Bcl-2 family members reactivates TRAIL-induced apoptosis in malignant glioma

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CHOP is involved in endoplasmic reticulum stress-induced apoptosis by enhancing DR5 expression in human carcinoma cells

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Proteasome inhibitor MG132 induces death receptor 5 through CCAAT/enhancer-binding protein homologous protein

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Apoptosis induced by proteasome inhibition in cancer cells: predominant role of the p53/PUMA pathway

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KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene

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Induction of the mammalian stress response gene GADD153 by oxidative stress: role of AP-1 element

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APO2 ligand: a novel lethal weapon against malignant glioma?

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Augmenting chemosensitivity of malignant melanoma tumors via proteasome inhibition: implication for bortezomib (VELCADE, PS-341) as a therapeutic agent for malignant melanoma

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Proteasome inhibitor MG132 upregulates death receptor 5 and cooperates with Apo2L/TRAIL to induce apoptosis in Bax-proficient and -deficient cells

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The TRAIL apoptotic pathway mediates proteasome inhibitor induced apoptosis in primary chronic lymphocytic leukemia cells

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Enhanced caspase-8 recruitment to and activation at the DISC is critical for sensitisation of human hepatocellular carcinoma cells to TRAIL-induced apoptosis by chemotherapeutic drugs.

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Proteasome inhibitors trigger NOXA-mediated apoptosis in melanoma and myeloma cells

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Proteasome inhibitors induce p53/p21-independent apoptosis in human glioma cells

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Proteasome inhibitor PS-341 causes cell growth arrest and apoptosis in human glioblastoma multiforme (GBM).

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