Myc down-regulation as a mechanism to activate the Rb pathway in STAT5A-induced senescence. (Q40072601)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17913706%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

title

Myc down-regulation as a mechanism to activate the Rb pathway in STAT5A-induced senescence (English)

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8 January 2020

1

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8 January 2020

author name string

Marie-France Gaumont-Leclerc

series ordinal

2

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8 January 2020

Geneviève Huot

series ordinal

3

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8 January 2020

Gerardo Ferbeyre

series ordinal

4

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8 January 2020

language of work or name

English

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publication date

3 October 2007

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Journal of Biological Chemistry

8 January 2020

published in

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8 January 2020

volume

282

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8 January 2020

issue

48

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8 January 2020

page(s)

34938-34944

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Pocket proteins and cell cycle control

8 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707074200

E2Fs regulate the expression of genes involved in differentiation, development, proliferation, and apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707074200

Cellular response to oncogenic ras involves induction of the Cdk4 and Cdk6 inhibitor p15(INK4b)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707074200

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707074200

Biallelic mutations in p16(INK4a) confer resistance to Ras- and Ets-induced senescence in human diploid fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707074200

The DNA damage signaling pathway is a critical mediator of oncogene-induced senescence.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707074200

Identification and characterization of a constitutively active STAT5 mutant that promotes cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707074200

Src kinases mediate STAT growth pathways in squamous cell carcinoma of the head and neck

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707074200

Human fibroblasts require the Rb family of tumor suppressors, but not p53, for PML-induced senescence.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707074200

Dose-dependent oncogene-induced senescence in vivo and its evasion during mammary tumorigenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707074200

Stat5a is mandatory for adult mammary gland development and lactogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707074200

Stat5 in the mammary gland: controlling normal development and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707074200

Loss of Stat5a delays mammary cancer progression in a mouse model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707074200

Stat5a is tyrosine phosphorylated and nuclear localized in a high proportion of human breast cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707074200

Intrinsic tumour suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707074200

Increased ezrin expression and activation by CDK5 coincident with acquisition of the senescent phenotype.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707074200

Identification of CDK4 as a target of c-MYC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707074200

Reversible kinetic analysis of Myc targets in vivo provides novel insights into Myc-mediated tumorigenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707074200

Repression of p15INK4b expression by Myc through association with Miz-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707074200

c-Myc localization within the nucleus: evidence for association with the PML nuclear body

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707074200

PML interacts with Myc, and Myc target gene expression is altered in PML-null fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707074200

PML4 induces differentiation by Myc destabilization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707074200

The IL-2 receptor promotes lymphocyte proliferation and induction of the c-myc, bcl-2, and bcl-x genes through the trans-activation domain of Stat5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707074200

Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707074200

Reduced c-Myc signaling triggers telomere-independent senescence by regulating Bmi-1 and p16(INK4a).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707074200

Cellular senescence is an important mechanism of tumor regression upon c-Myc inactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707074200

Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707074200

Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707074200

Immortalization of primary human prostate epithelial cells by c-Myc.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707074200

Amino-terminal domains of c-myc and N-myc proteins mediate binding to the retinoblastoma gene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707074200

A genetic screen to identify genes that rescue the slow growth phenotype of c-myc null fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707074200

E1A-dependent trans-activation of the human MYC promoter is mediated by the E2F factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707074200

PML is a direct p53 target that modulates p53 effector functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707074200

Ras enhances Myc protein stability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707074200

Identification of c-MYC as a target of the APC pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707074200

The tumor suppressor KLF11 mediates a novel mechanism in transforming growth factor beta-induced growth inhibition that is inactivated in pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707074200

Increased rate of degradation of c-myc mRNA in interferon-treated Daudi cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707074200

Rapid cytoplasmic turnover of c-myc mRNA: requirement of the 3' untranslated sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707074200

Selective activation of STAT5 unveils its role in stem cell self-renewal in normal and leukemic hematopoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707074200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707074200

Mutations of the tumor suppressor gene SOCS-1 in classical Hodgkin lymphoma are frequent and associated with nuclear phospho-STAT5 accumulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707074200

The role of Stat5 in estrogen receptor-positive breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707074200

Signal transducer and activator of transcription-5 activation and breast cancer prognosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707074200

Mutational inactivation of the p53 gene in the human erythroid leukemic K562 cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707074200

Cytokine receptor signalling and aging.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707074200

Stat5 tetramer formation is associated with leukemogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707074200

A block to elongation is largely responsible for decreased transcription of c-myc in differentiated HL60 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707074200

21 January 2018

Identifiers

DOI

10.1074/JBC.M707074200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17913706%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

1 reference