Stabilization of p53 in human cytomegalovirus-initiated cells is associated with sequestration of HDM2 and decreased p53 ubiquitination (Q40094191)

17 September 2017

Stabilization of p53 in human cytomegalovirus-initiated cells is associated with sequestration of HDM2 and decreased p53 ubiquitination (English)

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17 September 2017

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protein ubiquitination

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Zhenping Chen

1

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17 September 2017

Eugene Knutson

2

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17 September 2017

Shuo Wang

3

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17 September 2017

Luis A Martinez

4

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17 September 2017

Thomas Albrecht

5

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17 September 2017

language of work or name

English

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publication date

13 August 2007

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Journal of Biological Chemistry

17 September 2017

12

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based on heuristic

inferred from page(s)

published in

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17 September 2017

282

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17 September 2017

40

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17 September 2017

29284-29295

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Human cytomegalovirus: clinical aspects, immune regulation, and emerging treatments.

17 September 2017

1 reference

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Human cytomegalovirus inhibits cellular DNA synthesis and arrests productively infected cells in late G1.

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Human cytomegalovirus stimulates arachidonic acid metabolism through pathways that are affected by inhibitors of phospholipase A2 and protein kinase C.

21 January 2018

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Receptor-Initiated Activation of Cells and Their Oncogenes by Herpes-Family Viruses

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Ca2+ responses in cytomegalovirus-infected fibroblasts of human origin

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Cellular stress and signal transduction responses to human cytomegalovirus infection

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Activation of Proto-Oncogenes: an Immediate Early Event in Human Cytomegalovirus Infection

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Epidermal growth factor receptor is a cellular receptor for human cytomegalovirus

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Integrin alphavbeta3 is a coreceptor for human cytomegalovirus

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Degradation of p21cip1 in cells productively infected with human cytomegalovirus

21 January 2018

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The cyclin E promoter is activated by human cytomegalovirus 86-kDa immediate early protein

21 January 2018

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Cellular gene expression altered by human cytomegalovirus: global monitoring with oligonucleotide arrays

21 January 2018

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Human cytomegalovirus immediate early proteins and cell growth control

21 January 2018

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Human cytomegalovirus immediate early proteins upregulate endothelial p53 function.

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Human tumor suppressor p53 and DNA viruses

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Combined In Situ Hybridization and Immunohistochemistry for Automated Detection of Cytomegalovirus and p53.

21 January 2018

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Surfing the p53 network

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p53 and disease: when the guardian angel fails

21 January 2018

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TP53: a key gene in human cancer.

21 January 2018

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Regulating the p53 system through ubiquitination

21 January 2018

1 reference

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Mapping of the p53 and mdm-2 interaction domains

21 January 2018

1 reference

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Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53

21 January 2018

1 reference

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Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain

21 January 2018

1 reference

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Structural details on mdm2-p53 interaction

21 January 2018

1 reference

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Nuclear export is required for degradation of endogenous p53 by MDM2 and human papillomavirus E6

21 January 2018

1 reference

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Polyubiquitination of p53 by a ubiquitin ligase activity of p300.

21 January 2018

1 reference

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Multiple ribosomal RNA cleavage pathways in mammalian cells

21 January 2018

1 reference

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The major calpain isozymes are long-lived proteins. Design of an antisense strategy for calpain depletion in cultured cells

21 January 2018

1 reference

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The structure-function relationship between peptide aldehyde derivatives on initiation of neurite outgrowth in PC12h cells

21 January 2018

1 reference

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p53 ubiquitination: Mdm2 and beyond

21 January 2018

1 reference

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Pirh2, a p53-induced ubiquitin-protein ligase, promotes p53 degradation

21 January 2018

1 reference

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The ubiquitin ligase COP1 is a critical negative regulator of p53

21 January 2018

1 reference

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Topors functions as an E3 ubiquitin ligase with specific E2 enzymes and ubiquitinates p53

21 January 2018

1 reference

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Design, synthesis, and evaluation of novel boronic-chalcone derivatives as antitumor agents

21 January 2018

1 reference

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Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53

21 January 2018

1 reference

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Nucleocytoplasmic shuttling of oncoprotein Hdm2 is required for Hdm2-mediated degradation of p53

21 January 2018

1 reference

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Evidence that the human cytomegalovirus IE2-86 protein binds mdm2 and facilitates mdm2 degradation

21 January 2018

1 reference

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Cellular oncogene activation by human cytomegalovirus Lack of correlation with virus infectivity and immediate early gene expression

21 January 2018

1 reference

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Immediate early antigens in human cytomegalovirus infected cells

21 January 2018

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The ubiquitin-proteasome pathway: the complexity and myriad functions of proteins death

21 January 2018

1 reference

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MDM2 is a central node in the p53 pathway: 12 years and counting

21 January 2018

1 reference

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p300/MDM2 complexes participate in MDM2-mediated p53 degradation

21 January 2018

1 reference

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Nucleo-cytoplasmic shuttling of the hdm2 oncoprotein regulates the levels of the p53 protein via a pathway used by the human immunodeficiency virus rev protein.

21 January 2018

1 reference

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Cocompartmentalization of p53 and Mdm2 is a major determinant for Mdm2-mediated degradation of p53.

21 January 2018

1 reference

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Mono- versus polyubiquitination: differential control of p53 fate by Mdm2.

21 January 2018

1 reference

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Disruption of the nucleolus mediates stabilization of p53 in response to DNA damage and other stresses

21 January 2018

1 reference

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Cytomegalovirus: An Ultrastructural Study of the Morphogenesis of Nuclear Inclusions in Human Cell Culture

21 January 2018

1 reference

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ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways

21 January 2018

1 reference

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The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2.

21 January 2018

1 reference

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P19(ARF) stabilizes p53 by blocking nucleo-cytoplasmic shuttling of Mdm2

21 January 2018

1 reference

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The ribosomal L5 protein is associated with mdm-2 and mdm-2-p53 complexes

21 January 2018

1 reference

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Inhibition of MDM2-mediated p53 ubiquitination and degradation by ribosomal protein L5

21 January 2018

1 reference

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Inhibition of cell division by the human cytomegalovirus IE86 protein: role of the p53 pathway or cyclin-dependent kinase 1/cyclin B1.

21 January 2018

1 reference

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Human cytomegalovirus causes endothelial injury through the ataxia telangiectasia mutant and p53 DNA damage signaling pathways

21 January 2018

1 reference

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Human cytomegalovirus inhibits a DNA damage response by mislocalizing checkpoint proteins

21 January 2018

1 reference

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ATM complexes with HDM2 and promotes its rapid phosphorylation in a p53-independent manner in normal and tumor human cells exposed to ionizing radiation

21 January 2018

1 reference

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Mdm2-mediated NEDD8 conjugation of p53 inhibits its transcriptional activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705349200

Human cytomegalovirus infection results in altered Cdk2 subcellular localization

21 January 2018

1 reference

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Replication of human cytomegalovirus at supra-optimal temperatures is dependent on the virus strain, multiplicity of infection and phase of virus replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705349200

21 January 2018

Identifiers

DOI

10.1074/JBC.M705349200

1 reference

17 September 2017

1 reference