Transforming growth factor beta suppresses human telomerase reverse transcriptase (hTERT) by Smad3 interactions with c-Myc and the hTERT gene (Q40265633)

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scientific article published on 19 June 2006

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English	Transforming growth factor beta suppresses human telomerase reverse transcriptase (hTERT) by Smad3 interactions with c-Myc and the hTERT gene	scientific article published on 19 June 2006

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

Transforming growth factor beta suppresses human telomerase reverse transcriptase (hTERT) by Smad3 interactions with c-Myc and the hTERT gene (English)

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

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Europe PubMed Central

PubMed publication ID

19 September 2017

author name string

He Li

1

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Europe PubMed Central

PubMed publication ID

19 September 2017

Jinhua Li

3

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Europe PubMed Central

PubMed publication ID

19 September 2017

Michael C Berndt

4

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Europe PubMed Central

PubMed publication ID

19 September 2017

Jun-Ping Liu

5

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

language of work or name

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publication date

19 June 2006

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Europe PubMed Central

PubMed publication ID

19 September 2017

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

19 September 2017

281

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Europe PubMed Central

PubMed publication ID

19 September 2017

35

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Europe PubMed Central

PubMed publication ID

19 September 2017

25588-25600

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Europe PubMed Central

PubMed publication ID

19 September 2017

Telomeres and telomerase: their mechanisms of action and the effects of altering their functions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602381200

21 January 2018

Telomeres and human disease: ageing, cancer and beyond

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602381200

21 January 2018

Telomere and telomerase dynamics in human cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602381200

21 January 2018

Telomeric DNA in ALT cells is characterized by free telomeric circles and heterogeneous t-loops

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602381200

21 January 2018

Amplification of telomeric arrays via rolling-circle mechanism

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602381200

21 January 2018

Telomere elongation by hnRNP A1 and a derivative that interacts with telomeric repeats and telomerase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602381200

21 January 2018

Overexpression of telomerase confers growth advantage, stress resistance, and enhanced differentiation of ESCs toward the hematopoietic lineage.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602381200

21 January 2018

Human telomerase reverse transcriptase immortalizes bovine lens epithelial cells and suppresses differentiation through regulation of the ERK signaling pathway.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602381200

21 January 2018

Telomerase down-regulation does not mediate PC12 pheochromocytoma cell differentiation induced by NGF, but requires MAP kinase signalling.

1 reference

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21 January 2018

Effects of telomerase and telomere length on epidermal stem cell behavior

1 reference

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21 January 2018

Conditional telomerase induction causes proliferation of hair follicle stem cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602381200

21 January 2018

Extension of life-span by introduction of telomerase into normal human cells

1 reference

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21 January 2018

Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602381200

21 January 2018

Senescence and immortalization: role of telomeres and telomerase

1 reference

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21 January 2018

The human telomerase catalytic subunit hTERT: organization of the gene and characterization of the promoter

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602381200

21 January 2018

Direct examination of histone acetylation on Myc target genes using chromatin immunoprecipitation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602381200

21 January 2018

Sp1 cooperates with c-Myc to activate transcription of the human telomerase reverse transcriptase gene (hTERT).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602381200

21 January 2018

Transcriptional regulation and transformation by Myc proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602381200

21 January 2018

Direct activation of TERT transcription by c-MYC.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602381200

21 January 2018

Switch from Myc/Max to Mad1/Max binding and decrease in histone acetylation at the telomerase reverse transcriptase promoter during differentiation of HL60 cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602381200

21 January 2018

Function of AP-1 in transcription of the telomerase reverse transcriptase gene (TERT) in human and mouse cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602381200

21 January 2018

Identification of a Drosophila activin receptor

1 reference

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21 January 2018

Transforming growth factor-beta signal transduction in epithelial cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602381200

21 January 2018

Hierarchical model of gene regulation by transforming growth factor beta

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602381200

21 January 2018

Smad transcription factors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602381200

21 January 2018

Mechanisms of TGF-beta signaling from cell membrane to the nucleus

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602381200

21 January 2018

TGF-beta signalling from cell membrane to nucleus through SMAD proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602381200

21 January 2018

Transforming growth factor beta triggers two independent-senescence programs in cancer cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602381200

21 January 2018

Repeated exposure of human skin fibroblasts to UVB at subcytotoxic level triggers premature senescence through the TGF-beta1 signaling pathway.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602381200

21 January 2018

Expression of the telomerase catalytic subunit, hTERT, induces resistance to transforming growth factor beta growth inhibition in p16INK4A(-) human mammary epithelial cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602381200

21 January 2018

Smurf2 up-regulation activates telomere-dependent senescence

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602381200

21 January 2018

Direct activation of telomerase by EGF through Ets-mediated transactivation of TERT via MAP kinase signaling pathway.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602381200

21 January 2018

Inhibition of the epidermal growth factor receptor suppresses telomerase activity in HSC-1 human cutaneous squamous cell carcinoma cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602381200

21 January 2018

Multiple tumor suppressor pathways negatively regulate telomerase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602381200

21 January 2018

Hyperactivation of Stat3 in gp130 mutant mice promotes gastric hyperproliferation and desensitizes TGF-beta signaling.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602381200

21 January 2018

Smad7 differentially regulates transforming growth factor beta-mediated signaling pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602381200

21 January 2018

Expression of telomerase RNA template, but not telomerase reverse transcriptase, is limiting for telomere length maintenance in vivo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602381200

21 January 2018

Telomerase is controlled by protein kinase Calpha in human breast cancer cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602381200

21 January 2018

Cytostatic and apoptotic actions of TGF-beta in homeostasis and cancer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602381200

21 January 2018

Smad-dependent and Smad-independent pathways in TGF-beta family signalling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602381200

21 January 2018

Downstream E-box-mediated regulation of the human telomerase reverse transcriptase (hTERT) gene transcription: evidence for an endogenous mechanism of transcriptional repression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602381200

21 January 2018

Cyclin-dependent kinases regulate the antiproliferative function of Smads

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602381200

21 January 2018

Role of Rho/ROCK and p38 MAP kinase pathways in transforming growth factor-beta-mediated Smad-dependent growth inhibition of human breast carcinoma cells in vivo

1 reference

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21 January 2018

Cross-talk between IGF-I and TGF-beta signaling pathways

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https://api.crossref.org/works/10.1074%2FJBC.M602381200

21 January 2018

Gradual phenotypic conversion associated with immortalization of cultured human mammary epithelial cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602381200

21 January 2018

Smads bind directly to the Jun family of AP-1 transcription factors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602381200

21 January 2018

Smad3 mutant mice develop metastatic colorectal cancer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602381200

21 January 2018

Targeted disruption of Smad3 reveals an essential role in transforming growth factor beta-mediated signal transduction

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21 January 2018

Regulation of p53 function and stability by phosphorylation

1 reference

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21 January 2018

Targeted disruption of SMAD3 results in impaired mucosal immunity and diminished T cell responsiveness to TGF-beta

1 reference

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21 January 2018

Loss of Smad3 in acute T-cell lymphoblastic leukemia.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602381200

21 January 2018

Direct interaction of c-Myc with Smad2 and Smad3 to inhibit TGF-beta-mediated induction of the CDK inhibitor p15(Ink4B)

1 reference

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21 January 2018

E2F4/5 and p107 as Smad cofactors linking the TGFbeta receptor to c-myc repression

1 reference

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21 January 2018

Risky immortalization by telomerase

1 reference

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21 January 2018

Identifiers

10.1074/JBC.M602381200

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

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