A genome-wide RNA interference screen identifies a differential role of the mediator CDK8 module subunits for GATA/ RUNX-activated transcription in Drosophila. (Q40754406)

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scientific article published on 5 April 2010

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English	A genome-wide RNA interference screen identifies a differential role of the mediator CDK8 module subunits for GATA/ RUNX-activated transcription in Drosophila.	scientific article published on 5 April 2010

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30 January 2020

A genome-wide RNA interference screen identifies a differential role of the mediator CDK8 module subunits for GATA/ RUNX-activated transcription in Drosophila (English)

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30 January 2020

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RNA interference

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based on heuristic

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Michael Boutros

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Vanessa Gobert

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Dani Osman

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Stéphanie Bras

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Benoit Augé

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Muriel Boube

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Henri-Marc Bourbon

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Thomas Horn

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Molecular and Cellular Biology

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30 January 2020

GenomeRNAi: a database for cell-based RNAi phenotypes. 2009 update.

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Gatekeeper function of the RUNX1 transcription factor in acute leukemia

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The GATA factor Serpent cross-regulates lozenge and u-shaped expression during Drosophila blood cell development

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Regulation of RUNX1 transcriptional function by GATA-1.

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CDK8 is a stimulus-specific positive coregulator of p53 target genes

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Distinct roles for Mediator Cdk8 module subunits in Drosophila development.

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Genome-wide location of the coactivator mediator: Binding without activation and transient Cdk8 interaction on DNA.

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Physical association of the patient-specific GATA1 mutants with RUNX1 in acute megakaryoblastic leukemia accompanying Down syndrome

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Runx1 binds positive transcription elongation factor b and represses transcriptional elongation by RNA polymerase II: possible mechanism of CD4 silencing

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Mediator as a general transcription factor

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GATA transcription factors in hematologic disease

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Mediator expression profiling epistasis reveals a signal transduction pathway with antagonistic submodules and highly specific downstream targets

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GATA-1: one protein, many partners.

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Identification of JAK/STAT signalling components by genome-wide RNA interference.

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Structure of eukaryotic Mediator complexes

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Dynamic regulation of pol II transcription by the mammalian Mediator complex

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The mammalian Mediator complex and its role in transcriptional regulation

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The yeast Mediator complex and its regulation

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Mediator and the mechanism of transcriptional activation

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Developmental control via GATA factor interplay at chromatin domains

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Gene expression regulation and domain function of hematopoietic GATA factors

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Identification and characterization of genes involved in embryonic crystal cell formation during Drosophila hematopoiesis

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Core-binding factors in hematopoiesis and immune function

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RUNX1 and GATA-1 coexpression and cooperation in megakaryocytic differentiation

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Two isoforms of Serpent containing either one or two GATA zinc fingers have different roles in Drosophila haematopoiesis

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Mediator is a transducer of Wnt/beta-catenin signaling.

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The two origins of hemocytes in Drosophila.

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A molecular aspect of hematopoiesis and endoderm development common to vertebrates and Drosophila

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A genome-wide RNA interference screen in Drosophila melanogaster cells for new components of the Hh signaling pathway

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2 December 2018

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10.1128/MCB.01625-09

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30 January 2020

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