BAX channel activity mediates lysosomal disruption linked to Parkinson disease. (Q42364834)

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12 March 2020

title

BAX channel activity mediates lysosomal disruption linked to Parkinson disease (English)

1 reference

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12 March 2020

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8

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12 March 2020

Marta Martinez-vicente

2

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12 March 2020

Benjamin Dehay

3

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12 March 2020

Ariadna Recasens

5

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12 March 2020

author name string

Jordi Bové

1

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12 March 2020

Celine Perier

4

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12 March 2020

Agnes Bombrun

6

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12 March 2020

Bruno Antonsson

7

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12 March 2020

publication date

26 March 2014

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12 March 2020

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12 March 2020

volume

10

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12 March 2020

issue

5

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12 March 2020

page(s)

889-900

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describes a project that uses

12 March 2020

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5119069/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

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TFEB-mediated autophagy rescues midbrain dopamine neurons from α-synuclein toxicity

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Lysosomal impairment in Parkinson's disease

29 May 2018

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Optic atrophy 1 mediates mitochondria remodeling and dopaminergic neurodegeneration linked to complex I deficiency.

29 May 2018

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Loss of P-type ATPase ATP13A2/PARK9 function induces general lysosomal deficiency and leads to Parkinson disease neurodegeneration.

29 May 2018

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Deficiency of ATP13A2 leads to lysosomal dysfunction, α-synuclein accumulation, and neurotoxicity

29 May 2018

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Mitochondria and programmed cell death in Parkinson's disease: apoptosis and beyond

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Bcl-x(L) retrotranslocates Bax from the mitochondria into the cytosol

29 May 2018

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Pathogenic lysosomal depletion in Parkinson's disease

29 May 2018

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MAC inhibitors suppress mitochondrial apoptosis

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29 May 2018

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Autophagic cell death: the story of a misnomer

29 May 2018

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Tumor necrosis factor-related apoptosis-inducing ligand activates a lysosomal pathway of apoptosis that is regulated by Bcl-2 proteins

29 May 2018

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Two molecular pathways initiate mitochondria-dependent dopaminergic neurodegeneration in experimental Parkinson's disease

29 May 2018

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Protocol for the MPTP mouse model of Parkinson's disease

29 May 2018

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Bax inhibition protects against free fatty acid-induced lysosomal permeabilization

29 May 2018

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Complex I deficiency primes Bax-dependent neuronal apoptosis through mitochondrial oxidative damage

29 May 2018

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Bax channel inhibitors prevent mitochondrion-mediated apoptosis and protect neurons in a model of global brain ischemia.

29 May 2018

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Lysosomal membrane permeabilization during apoptosis--involvement of Bax?

29 May 2018

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29 May 2018

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Caspase-9 activation results in downstream caspase-8 activation and bid cleavage in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease

29 May 2018

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Bax ablation prevents dopaminergic neurodegeneration in the 1-methyl- 4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease

29 May 2018

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29 May 2018

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29 May 2018

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29 May 2018

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29 May 2018

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29 May 2018

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Lysosomal membrane permeabilization and cathepsin release is a Bax/Bak-dependent, amplifying event of apoptosis in fibroblasts and monocytes.

17 August 2018

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Alterations in lysosomal and proteasomal markers in Parkinson's disease: relationship to alpha-synuclein inclusions.

17 August 2018

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Membrane-permeable Bcl-xL prevents MPTP-induced dopaminergic neuronal loss in the substantia nigra.

17 August 2018

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Tumor necrosis factor-alpha-associated lysosomal permeabilization is cathepsin B dependent

17 August 2018

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Parkinson-like neurodegeneration induced by targeted overexpression of alpha-synuclein in the nigrostriatal system.

17 August 2018

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Is Bax a mitochondrial mediator in apoptotic death of dopaminergic neurons in Parkinson's disease?

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5119069

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyride neurotoxicity is attenuated in mice overexpressing Bcl-2.

17 August 2018

1 reference

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Lysosomal membrane permeabilization in Parkinson disease

17 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.4161%2FAUTO.28286

21 January 2018

Identifiers

DOI

10.4161/AUTO.28286

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24686337%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24686337%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

1 reference