TFEB-mediated autophagy rescues midbrain dopamine neurons from α-synuclein toxicity (Q36835587)

16 August 2017

TFEB-mediated autophagy rescues midbrain dopamine neurons from α-synuclein toxicity (English)

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16 August 2017

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6

Anders Björklund

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Johan Jakobsson

object named as

Johan Jakobsson

5

0 references

Pia Weikop

3

object named as

Pia Weikop

1 reference

16 August 2017

Mickael Decressac

1

1 reference

16 August 2017

Bengt Mattsson

2

1 reference

16 August 2017

Martin Lundblad

4

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16 August 2017

language of work or name

English

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publication date

22 April 2013

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Proceedings of the National Academy of Sciences of the United States of America

16 August 2017

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16 August 2017

110

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16 August 2017

E1817-26

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16 August 2017

19

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describes a project that uses

16 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3651458/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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Conditional expression of Parkinson's disease-related mutant α-synuclein in the midbrain dopaminergic neurons causes progressive neurodegeneration and degradation of transcription factor nuclear receptor related 1

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Increased efficacy of the 6-hydroxydopamine lesion of the median forebrain bundle in small rats, by modification of the stereotaxic coordinates.

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Loss of autophagy in the central nervous system causes neurodegeneration in mice

29 September 2017

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Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice

29 September 2017

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Regulation of intracellular accumulation of mutant Huntingtin by Beclin 1

29 September 2017

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Viral vector mediated overexpression of human alpha-synuclein in the nigrostriatal dopaminergic neurons: a new model for Parkinson's disease.

29 September 2017

1 reference

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Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy

29 September 2017

1 reference

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Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3651458

Production methods for gene transfer vectors based on adeno-associated virus serotypes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3651458

A role for alpha-synuclein in the regulation of dopamine biosynthesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3651458

Chaperone-like activity of synucleins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3651458

alpha-Synuclein shares physical and functional homology with 14-3-3 proteins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3651458

Melanized dopaminergic neurons are differentially susceptible to degeneration in Parkinson's disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3651458

Autophagy induction reduces mutant ataxin-3 levels and toxicity in a mouse model of spinocerebellar ataxia type 3

29 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3651458

Wild type alpha-synuclein is degraded by chaperone-mediated autophagy and macroautophagy in neuronal cells

27 June 2018

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Parkinson's disease: loss of neurons from the ventral tegmental area contralateral to therapeutic surgical lesions

27 June 2018

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Genetic analysis of the LAMP-2 gene promoter in patients with sporadic Parkinson's disease.

27 June 2018

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Alterations in lysosomal and proteasomal markers in Parkinson's disease: relationship to alpha-synuclein inclusions.

5 September 2018

1 reference

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Monitoring autophagic degradation of p62/SQSTM1.

5 September 2018

1 reference

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Clearance of alpha-synuclein oligomeric intermediates via the lysosomal degradation pathway.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3651458

α-Synuclein Is Degraded by Both Autophagy and the Proteasome

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3651458

14-3-3 protein is a component of Lewy bodies in Parkinson's disease-mutation analysis and association studies of 14-3-3 eta.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3651458

Parkinson-like neurodegeneration induced by targeted overexpression of alpha-synuclein in the nigrostriatal system.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3651458

14-3-3 proteins in Lewy bodies in Parkinson disease and diffuse Lewy body disease brains

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3651458

Recombinant adeno-associated virus purification using novel methods improves infectious titer and yield

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3651458

5 September 2018

Identifiers

DOI

10.1073/PNAS.1305623110

1 reference

16 August 2017

0 references

1 reference

16 August 2017

1 reference