The music of lipids: how lipid composition orchestrates cellular behaviour (Q42501205)

1 November 2017

The music of lipids: how lipid composition orchestrates cellular behaviour (English)

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1 November 2017

4

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1 November 2017

Zachary T Schug

1

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Christian Frezza

object named as

Christian Frezza

series ordinal

2

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author name string

Laura C A Galbraith

series ordinal

3

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1 November 2017

30 January 2012

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1 November 2017

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1 November 2017

51

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1 November 2017

301-310

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1 November 2017

3

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Fatty acid synthesis: a potential selective target for antineoplastic therapy

1 November 2017

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

Fatty acid synthase as a potential therapeutic target in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

RNA interference-mediated silencing of the acetyl-CoA-carboxylase-alpha gene induces growth inhibition and apoptosis of prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

Control of cell growth and survival by enzymes of the fatty acid synthesis pathway in HCT-116 colon cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

ATP citrate lyase is an important component of cell growth and transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

ATP citrate lyase inhibition can suppress tumor cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

Fatty acid synthase inhibition in human breast cancer cells leads to malonyl-CoA-induced inhibition of fatty acid oxidation and cytotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

Acetyl-CoA carboxylase alpha is essential to breast cancer cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

Inhibition of fatty-acid synthase induces caspase-8-mediated tumor cell apoptosis by up-regulating DDIT4.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

Positive feedback regulation between AKT activation and fatty acid synthase expression in ovarian carcinoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

Fatty acid synthase inhibitor cerulenin suppresses liver metastasis of colon cancer in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

Fatty acid synthase inhibitors cerulenin and C75 retard growth and induce caspase-dependent apoptosis in human melanoma A-375 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

Inhibition of fatty acid synthase in melanoma cells activates the intrinsic pathway of apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

Mechanism of apoptosis induced by the inhibition of fatty acid synthase in breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

Inhibition of fatty acid synthase induces endoplasmic reticulum stress in tumor cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

Inhibition of fatty acid synthase by Orlistat accelerates gastric tumor cell apoptosis in culture and increases survival rates in gastric tumor bearing mice in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

De novo lipogenesis protects cancer cells from free radicals and chemotherapeutics by promoting membrane lipid saturation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

Increased lipogenesis in cancer cells: new players, novel targets.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

Lipid rafts: signaling and sorting platforms of cells and their roles in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

Fatty acid synthase: a metabolic oncogene in prostate cancer?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

Saturated fatty acids modulate cell response to DNA damage: implication for their role in tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

Fatty acid synthase: a metabolic enzyme and candidate oncogene in prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

Inhibition of fatty acid synthase (FAS) suppresses HER2/neu (erbB-2) oncogene overexpression in cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

Targeting fatty acid synthase-driven lipid rafts: a novel strategy to overcome trastuzumab resistance in breast cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

Nonbilayer lipids affect peripheral and integral membrane proteins via changes in the lateral pressure profile.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

Lipid polymorphism and the functional roles of lipids in biological membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

Cardiolipin in energy transducing membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

The mitochondrial respiratory chain is partially organized in a supercomplex assembly: kinetic evidence using flux control analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

Cardiolipin stabilizes respiratory chain supercomplexes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

Mitochondrial respiratory chain supercomplexes are destabilized in Barth Syndrome patients

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

Cardiolipin biosynthesis and mitochondrial respiratory chain function are interdependent

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

Cardiolipin defines the interactome of the major ADP/ATP carrier protein of the mitochondrial inner membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

Absence of cardiolipin in the crd1 null mutant results in decreased mitochondrial membrane potential and reduced mitochondrial function

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

The genetic interactome of prohibitins: coordinated control of cardiolipin and phosphatidylethanolamine by conserved regulators in mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

A Drosophila model of Barth syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

The human dynamin-related protein OPA1 is anchored to the mitochondrial inner membrane facing the inter-membrane space

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

ChChd3, an inner mitochondrial membrane protein, is essential for maintaining crista integrity and mitochondrial function

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

Formation of cristae and crista junctions in mitochondria depends on antagonism between Fcj1 and Su e/g.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

OPA1 controls apoptotic cristae remodeling independently from mitochondrial fusion

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

Ultrastructural bases for metabolically linked mechanical activity in mitochondria. I. Reversible ultrastructural changes with change in metabolic steady state in isolated liver mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

A common lipid links Mfn-mediated mitochondrial fusion and SNARE-regulated exocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

Mitochondrial fusion and fission in cell life and death

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

Mitochondrial membrane biogenesis: phospholipids and proteins go hand in hand

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

Making heads or tails of phospholipids in mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

Role of cardiolipin alterations in mitochondrial dysfunction and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

Cytochrome c release from mitochondria proceeds by a two-step process

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

Cardiolipin deficiency releases cytochrome c from the inner mitochondrial membrane and accelerates stimuli-elicited apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

A distinct pathway remodels mitochondrial cristae and mobilizes cytochrome c during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

Opa1-mediated cristae opening is Bax/Bak and BH3 dependent, required for apoptosis, and independent of Bak oligomerization

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

An X-linked mitochondrial disease affecting cardiac muscle, skeletal muscle and neutrophil leucocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

The enigmatic role of tafazzin in cardiolipin metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

Role of calcium-independent phospholipase A2 in the pathogenesis of Barth syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

Cardiolipin acts as a mitochondrial signalling platform to launch apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

Cardiolipin provides an essential activating platform for caspase-8 on mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

BID is cleaved by caspase-8 within a native complex on the mitochondrial membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

Selective mitochondrial autophagy, or mitophagy, as a targeted defense against oxidative stress, mitochondrial dysfunction, and aging

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

Parkin-induced mitophagy in the pathogenesis of Parkinson disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

PINK1 is selectively stabilized on impaired mitochondria to activate Parkin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

Mitochondrial autophagy as a compensatory response to PINK1 deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

Loss of PINK1 function promotes mitophagy through effects on oxidative stress and mitochondrial fission

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

PINK1-dependent recruitment of Parkin to mitochondria in mitophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

The PINK1/Parkin pathway: a mitochondrial quality control system?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

Mitochondrial dynamics--fusion, fission, movement, and mitophagy--in neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

Disease-causing mutations in parkin impair mitochondrial ubiquitination, aggregation, and HDAC6-dependent mitophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

Fission and selective fusion govern mitochondrial segregation and elimination by autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

During autophagy mitochondria elongate, are spared from degradation and sustain cell viability.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

High levels of Fis1, a pro-fission mitochondrial protein, trigger autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

The interplay between mitochondrial dynamics and mitophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

Removal or masking of phosphatidylinositol(4,5)bisphosphate from the outer mitochondrial membrane causes mitochondrial fragmentation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

The dynamics of cardiolipin synthesis post-mitochondrial fusion

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

Divalent metal ion triggered activity of a synthetic antimicrobial in cardiolipin membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

Coassembly of Mgm1 isoforms requires cardiolipin and mediates mitochondrial inner membrane fusion

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

Cholesterol and peroxidized cardiolipin in mitochondrial membrane properties, permeabilization and cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

Purification and characterization of autophagosomes from rat hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

Mitochondria as a pharmacological target

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

In vivo and in vitro reconstitution of Atg8 conjugation essential for autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

Phospholipid biosynthesis in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

Mitochondria supply membranes for autophagosome biogenesis during starvation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

Autophagy counterbalances endoplasmic reticulum expansion during the unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

Exit from the Golgi is required for the expansion of the autophagosomal phagophore in yeast Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

Cardiolipin Clusters and Membrane Domain Formation Induced by Mitochondrial Proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F0284186X.2011.643823

10.3109/0284186X.2011.643823

21 January 2018

Identifiers

DOI

1 reference

1 November 2017

1 reference

PubMed ID

22283492