Insulin-degrading enzyme antagonizes insulin-dependent tissue growth and Abeta-induced neurotoxicity in Drosophila (Q43056852)

13 November 2017

title

Insulin-degrading enzyme antagonizes insulin-dependent tissue growth and Abeta-induced neurotoxicity in Drosophila (English)

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Insulin degrading metalloproteinase Dmel_CG5517

13 November 2017

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GOA release 2020-03-11

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3

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13 November 2017

Manabu Tsuda

1

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13 November 2017

Toshikazu Kobayashi

series ordinal

2

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13 November 2017

Toshiro Aigaki

series ordinal

4

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13 November 2017

language of work or name

English

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publication date

21 May 2010

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13 November 2017

number of pages

5

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based on heuristic

inferred from page(s)

published in

FEBS Letters

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13 November 2017

volume

584

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13 November 2017

issue

13

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13 November 2017

page(s)

2916-2920

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Insulin signalling and the regulation of glucose and lipid metabolism

13 November 2017

cites work

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Insulin degrading enzyme activity selectively decreases in the hippocampal formation of cases at high risk to develop Alzheimer's disease

21 January 2018

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Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivo

21 January 2018

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Partial loss-of-function mutations in insulin-degrading enzyme that induce diabetes also impair degradation of amyloid beta-protein

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An evolutionarily conserved function of the Drosophila insulin receptor and insulin-like peptides in growth control

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21 January 2018

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Drosophila PTEN regulates cell growth and proliferation through PI3K-dependent and -independent pathways

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Genetic Transformation of Drosophila with Transposable Element Vectors

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The calcineurin regulator sra plays an essential role in female meiosis in Drosophila

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Thioredoxin suppresses Parkin-associated endothelin receptor-like receptor-induced neurotoxicity and extends longevity in Drosophila

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Drosophila tumor suppressor PTEN controls cell size and number by antagonizing the Chico/PI3-kinase signaling pathway

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Alternative translation initiation generates a novel isoform of insulin-degrading enzyme targeted to mitochondria

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SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic beta cells

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21 January 2018

Identifiers

DOI

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13 November 2017

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