Alteration of Upstream Autophagy-Related Proteins (ULK1, ULK2, Beclin1, VPS34 and AMBRA1) in Lewy Body Disease (Q44152994)

30 November 2017

title

Alteration of Upstream Autophagy-Related Proteins (ULK1, ULK2, Beclin1, VPS34 and AMBRA1) in Lewy Body Disease (English)

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30 November 2017

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Yasuo Miki

1

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30 November 2017

Kunikazu Tanji

2

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30 November 2017

Fumiaki Mori

3

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30 November 2017

Jun Utsumi

4

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30 November 2017

Hidenao Sasaki

5

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Akiyoshi Kakita

6

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Hitoshi Takahashi

7

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30 November 2017

Koichi Wakabayashi

8

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30 November 2017

publication date

11 August 2015

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30 November 2017

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volume

26

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30 November 2017

issue

3

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30 November 2017

page(s)

359-370

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Neuropathological stageing of Alzheimer-related changes

30 November 2017

cites work

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Staging of brain pathology related to sporadic Parkinson's disease

21 January 2018

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Kinase-inactivated ULK proteins inhibit autophagy via their conserved C-terminal domains using an Atg13-independent mechanism

21 January 2018

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Autophagy in human health and disease

21 January 2018

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Beclin 1-independent pathway of damage-induced mitophagy and autophagic stress: implications for neurodegeneration and cell death

21 January 2018

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Pathogenic lysosomal depletion in Parkinson's disease

21 January 2018

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The dynamic interaction of AMBRA1 with the dynein motor complex regulates mammalian autophagy

21 January 2018

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Annular alpha-synuclein protofibrils are produced when spherical protofibrils are incubated in solution or bound to brain-derived membranes

21 January 2018

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Active, phosphorylation-dependent mitogen-activated protein kinase (MAPK/ERK), stress-activated protein kinase/c-Jun N-terminal kinase (SAPK/JNK), and p38 kinase expression in Parkinson's disease and Dementia with Lewy bodies.

21 January 2018

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ULK1.ATG13.FIP200 complex mediates mTOR signaling and is essential for autophagy

21 January 2018

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FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells

21 January 2018

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Role of cytochrome c as a stimulator of alpha-synuclein aggregation in Lewy body disease

21 January 2018

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Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy

21 January 2018

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Atg101, a novel mammalian autophagy protein interacting with Atg13

21 January 2018

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alpha-synuclein promotes mitochondrial deficit and oxidative stress

21 January 2018

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Macroautophagy in sporadic and the genetic form of Parkinson's disease with the A53T α-synuclein mutation

21 January 2018

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Beclin 1 forms two distinct phosphatidylinositol 3-kinase complexes with mammalian Atg14 and UVRAG

21 January 2018

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ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery

21 January 2018

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LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

21 January 2018

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LC3, GABARAP and GATE16 localize to autophagosomal membrane depending on form-II formation

21 January 2018

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The deacetylase HDAC6 regulates aggresome formation and cell viability in response to misfolded protein stress

21 January 2018

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AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

21 January 2018

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Neurodegenerative disease: amyloid pores from pathogenic mutations

21 January 2018

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Alpha-synuclein, especially the Parkinson's disease-associated mutants, forms pore-like annular and tubular protofibrils

21 January 2018

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The requirement of uncoordinated 51-like kinase 1 (ULK1) and ULK2 in the regulation of autophagy

21 January 2018

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Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG

21 January 2018

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GSK3-TIP60-ULK1 signaling pathway links growth factor deprivation to autophagy

21 January 2018

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Immunohistochemical evidence for macroautophagy in neurones and endothelial cells in Alzheimer's disease

21 January 2018

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Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages

21 January 2018

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Diagnosis and management of dementia with Lewy bodies: third report of the DLB Consortium

21 January 2018

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A novel, human Atg13 binding protein, Atg101, interacts with ULK1 and is essential for macroautophagy

21 January 2018

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mTOR inhibits autophagy by controlling ULK1 ubiquitylation, self-association and function through AMBRA1 and TRAF6.

21 January 2018

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Autophagy failure in Alzheimer's disease--locating the primary defect

21 January 2018

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Tor, a phosphatidylinositol kinase homologue, controls autophagy in yeast

21 January 2018

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Autophagic adapter protein NBR1 is localized in Lewy bodies and glial cytoplasmic inclusions and is involved in aggregate formation in α-synucleinopathy

21 January 2018

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Brain expression level and activity of HDAC6 protein in neurodegenerative dementia

21 January 2018

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Activation of neuronal extracellular receptor kinase (ERK) in Alzheimer disease links oxidative stress to abnormal phosphorylation

21 January 2018

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Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene

21 January 2018

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Depletion of Beclin-1 due to proteolytic cleavage by caspases in the Alzheimer's disease brain

21 January 2018

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ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase.

21 January 2018

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Accumulation of phosphorylated alpha-synuclein in aging human brain

21 January 2018

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TOR, a central controller of cell growth

21 January 2018

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Oxidative damage and mitochondrial decay in aging

21 January 2018

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Identification of Barkor as a mammalian autophagy-specific factor for Beclin 1 and class III phosphatidylinositol 3-kinase

21 January 2018

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Rubicon controls endosome maturation as a Rab7 effector

21 January 2018

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TRIM9, a novel brain-specific E3 ubiquitin ligase, is repressed in the brain of Parkinson's disease and dementia with Lewy bodies

21 January 2018

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Alteration of autophagosomal proteins (LC3, GABARAP and GATE-16) in Lewy body disease

21 January 2018

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Alteration of autophagosomal proteins in the brain of multiple system atrophy

21 January 2018

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NUB1 suppresses the formation of Lewy body-like inclusions by proteasomal degradation of synphilin-1

21 January 2018

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Parkin interacts with Ambra1 to induce mitophagy

21 January 2018

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Accumulation of alpha-synuclein/NACP is a cytopathological feature common to Lewy body disease and multiple system atrophy

21 January 2018

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The Lewy body in Parkinson's disease and related neurodegenerative disorders

21 January 2018

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Deconvoluting the context-dependent role for autophagy in cancer

21 January 2018

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Molecular determinants of selective clearance of protein inclusions by autophagy

21 January 2018

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Overexpression of human E46K mutant α-synuclein impairs macroautophagy via inactivation of JNK1-Bcl-2 pathway

21 January 2018

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Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor

21 January 2018

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Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complex

21 January 2018

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Identifiers

DOI

10.1111/BPA.12297

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30 November 2017

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