MicroRNA-based therapeutics in cardiovascular disease: screening and delivery to the target (Q45875338)

17 December 2017

review article

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title

MicroRNA-based therapeutics in cardiovascular disease: screening and delivery to the target (English)

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17 December 2017

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cardiovascular disease

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David Mellis

1

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17 December 2017

Andrea Caporali

series ordinal

2

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17 December 2017

publication date

1 December 2017

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17 December 2017

Biochemical Society Transactions

published in

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17 December 2017

Non-coding RNAs in human disease

cites work

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

Annotating non-coding regions of the genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

Regulation of translation initiation in eukaryotes: mechanisms and biological targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

The noncoding RNA revolution-trashing old rules to forge new ones

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

lincRNAs: genomics, evolution, and mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

Unique features of long non-coding RNA biogenesis and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

MicroRNAs: genomics, biogenesis, mechanism, and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

Small silencing RNAs: an expanding universe

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

Towards a molecular understanding of microRNA-mediated gene silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

Predicting effective microRNA target sites in mammalian mRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

Gene silencing by microRNAs: contributions of translational repression and mRNA decay

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

Analysis of CDS-located miRNA target sites suggests that they can effectively inhibit translation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

Identification and consequences of miRNA-target interactions--beyond repression of gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

New class of microRNA targets containing simultaneous 5'-UTR and 3'-UTR interaction sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

MicroRNA dysregulation in cancer: diagnostics, monitoring and therapeutics. A comprehensive review

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

MicroRNAs in Cardiovascular Disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

Therapeutic targeting of microRNAs: current status and future challenges

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

LNA-mediated microRNA silencing in non-human primates

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

Functional genomics applied to cardiovascular medicine

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

Microscopy-Based High-Content Screening.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

Knocking down the obstacles to functional genomics data sharing

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

High-Throughput Imaging for the Discovery of Cellular Mechanisms of Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

Developing microRNA screening as a functional genomics tool for disease research

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

Tiny giants of gene regulation: experimental strategies for microRNA functional studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

MicroRNA-520/373 family functions as a tumor suppressor in estrogen receptor negative breast cancer by targeting NF-κB and TGF-β signaling pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

MicroRNA-based discovery of barriers to dedifferentiation of fibroblasts to pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

Functional high-throughput screening identifies the miR-15 microRNA family as cellular restriction factors for Salmonella infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

Genome-wide functional screening of miR-23b as a pleiotropic modulator suppressing cancer metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

The microRNAs miR-373 and miR-520c promote tumour invasion and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

A phenotypic screen to identify hypertrophy-modulating microRNAs in primary cardiomyocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

Functional screening identifies miRNAs inducing cardiac regeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

Inhibition of miR-25 improves cardiac contractility in the failing heart.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

Antagonism of microRNA-122 in mice by systemically administered LNA-antimiR leads to up-regulation of a large set of predicted target mRNAs in the liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

Functional microRNA library screening identifies the hypoxamir miR-24 as a potent regulator of smooth muscle cell proliferation and vascularization

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

MicroRNA therapeutics: towards a new era for the management of cancer and other diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

Non-coding RNAs as drug targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

Targeting noncoding RNAs in disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

MicroRNAs 103 and 107 regulate insulin sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

Safety and activity of microRNA-loaded minicells in patients with recurrent malignant pleural mesothelioma: a first-in-man, phase 1, open-label, dose-escalation study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

MicroRNA-29, a key regulator of collagen expression in systemic sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

miR-34 - a microRNA replacement therapy is headed to the clinic

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

Nanoparticle-based therapy in an in vivo microRNA-155 (miR-155)-dependent mouse model of lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

Anti-microRNA-21 oligonucleotides prevent Alport nephropathy progression by stimulating metabolic pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

MicroRNA: A new therapeutic strategy for cardiovascular diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

Targeted delivery of miRNA therapeutics for cardiovascular diseases: opportunities and challenges.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

MicroRNAs in myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

Inhibition of miR-15 protects against cardiac ischemic injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

Regulation of neonatal and adult mammalian heart regeneration by the miR-15 family.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

Local inhibition of microRNA-24 improves reparative angiogenesis and left ventricle remodeling and function in mice with myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

MicroRNA-24 regulates vascularity after myocardial infarction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

miR-24 inhibits apoptosis and represses Bim in mouse cardiomyocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

MicroRNA regulation in angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

MicroRNAs in Postischemic Vascular Repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

Inhibition of 14q32 MicroRNAs miR-329, miR-487b, miR-494, and miR-495 increases neovascularization and blood flow recovery after ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

Overcoming cellular barriers for RNA therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

Evaluation of AAV-mediated Gene Therapy for Central Nervous System Disease in Canine Mucopolysaccharidosis VII.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

Prevalence of serum IgG and neutralizing factors against adeno-associated virus (AAV) types 1, 2, 5, 6, 8, and 9 in the healthy population: implications for gene therapy using AAV vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

Analysis of AAV serotypes 1-9 mediated gene expression and tropism in mice after systemic injection

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

Improved cardiac gene transfer by transcriptional and transductional targeting of adeno-associated viral vectors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

Non-viral vectors for gene-based therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

Materials for non-viral intracellular delivery of messenger RNA therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

Single-Dose Intracardiac Injection of Pro-Regenerative MicroRNAs Improves Cardiac Function After Myocardial Infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

Vascular endothelial growth factor-delivery systems for cardiac repair: an overview.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

Regulation of angiogenesis through the efficient delivery of microRNAs into endothelial cells using polyamine-coated carbon nanotubes

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

In vivo endothelial siRNA delivery using polymeric nanoparticles with low molecular weight

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

MicroRNA 139-5p coordinates APLNR-CXCR4 crosstalk during vascular maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

Increased local delivery of antagomir therapeutics to the rodent myocardium using ultrasound and microbubbles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

Ultrasound and microbubble mediated drug delivery: acoustic pressure as determinant for uptake via membrane pores or endocytosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

Ultrasound-targeted microbubble destruction-mediated microRNA-21 transfection regulated PDCD4/NF-κB/TNF-α pathway to prevent coronary microembolization-induced cardiac dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

Angiogenic gene therapy in cardiovascular diseases: dream or vision?

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

Gene therapy for the treatment of heart failure: promise postponed

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

Gene delivery technologies for cardiac applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

Intramyocardial cell delivery: observations in murine hearts

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

Cardiac positron emission tomography/computed tomography imaging accurately detects anatomically and functionally significant coronary artery disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

Intramyocardial Gene Therapy Directed to Hibernating Heart Muscle Using a Combination of Electromechanical Mapping and Positron Emission Tomography

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

Pervasive roles of microRNAs in cardiovascular biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

Enhanced gene and siRNA delivery by polycation-modified mesoporous silica nanoparticles loaded with chloroquine

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

Improved vectors and genome-wide libraries for CRISPR screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

CRISPRi-based genome-scale identification of functional long noncoding RNA loci in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20170037

21 January 2018

Identifiers

DOI

10.1042/BST20170037

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17 December 2017

PubMed ID

29196609

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17 December 2017