iPSC-Derived Human Microglia-like Cells to Study Neurological Diseases. (Q46001503)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28426964%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

title

iPSC-Derived Human Microglia-like Cells to Study Neurological Diseases (English)

1 reference

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18 March 2020

0 references

18

1 reference

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18 March 2020

Luke M. Healy

4

1 reference

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18 March 2020

Jack P. Antel

19

1 reference

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18 March 2020

Wayne W Poon

22

1 reference

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18 March 2020

Mathew Blurton-Jones

23

1 reference

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18 March 2020

author name string

Edsel M Abud

1

1 reference

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18 March 2020

Ricardo N Ramirez

2

1 reference

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18 March 2020

Eric S Martinez

3

1 reference

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18 March 2020

Cecilia H H Nguyen

5

1 reference

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18 March 2020

Sean A Newman

6

1 reference

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18 March 2020

Andriy V Yeromin

7

1 reference

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18 March 2020

Vanessa M Scarfone

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28426964%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

Samuel E Marsh

9

1 reference

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18 March 2020

Cristhian Fimbres

10

1 reference

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18 March 2020

Chad A Caraway

11

1 reference

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18 March 2020

Gianna M Fote

12

1 reference

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18 March 2020

Abdullah M Madany

13

1 reference

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18 March 2020

Anshu Agrawal

14

1 reference

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18 March 2020

Rakez Kayed

15

1 reference

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18 March 2020

Karen H Gylys

16

1 reference

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18 March 2020

Michael D Cahalan

17

1 reference

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18 March 2020

Ali Mortazavi

20

1 reference

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18 March 2020

Monica J Carson

21

1 reference

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18 March 2020

language of work or name

English

0 references

publication date

1 April 2017

1 reference

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18 March 2020

1 reference

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18 March 2020

volume

94

1 reference

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18 March 2020

issue

2

1 reference

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18 March 2020

page(s)

278-293.e9

1 reference

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describes a project that uses

18 March 2020

limma

1 reference

22 June 2022

https://europepmc.org/article/PMC/5482419

based on heuristic

inferred from PubMed Central ID database lookup

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TREM2 Binds to Apolipoproteins, Including APOE and CLU/APOJ, and Thereby Facilitates Uptake of Amyloid-Beta by Microglia.

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New insights on the role of microglia in synaptic pruning in health and disease

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22 June 2018

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22 June 2018

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Depletion of microglia and inhibition of exosome synthesis halt tau propagation

22 June 2018

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Role of pro-inflammatory cytokines released from microglia in Alzheimer's disease

22 June 2018

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Host microbiota constantly control maturation and function of microglia in the CNS.

22 June 2018

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22 June 2018

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P2Y12 expression and function in alternatively activated human microglia.

22 June 2018

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Environment drives selection and function of enhancers controlling tissue-specific macrophage identities

22 June 2018

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Tissue-resident macrophage enhancer landscapes are shaped by the local microenvironment.

22 June 2018

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22 June 2018

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22 June 2018

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22 June 2018

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Wnt signaling controls the specification of definitive and primitive hematopoiesis from human pluripotent stem cells

22 June 2018

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22 June 2018

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22 June 2018

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22 June 2018

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Mutant Huntingtin promotes autonomous microglia activation via myeloid lineage-determining factors

22 June 2018

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Identification of a unique TGF-β-dependent molecular and functional signature in microglia

22 June 2018

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Astrocytes mediate synapse elimination through MEGF10 and MERTK pathways

22 June 2018

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22 June 2018

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Functional screening in Drosophila identifies Alzheimer's disease susceptibility genes and implicates Tau-mediated mechanisms

22 June 2018

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Cerebral organoids model human brain development and microcephaly

22 June 2018

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Isolating, culturing, and polarizing primary human adult and fetal microglia.

22 June 2018

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CD33 Alzheimer's disease locus: altered monocyte function and amyloid biology

22 June 2018

1 reference

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Factors regulating microglia activation

22 June 2018

1 reference

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Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool

22 June 2018

1 reference

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Innate immunity in Alzheimer's disease: a complex affair

22 June 2018

1 reference

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Microglia emerge from erythromyeloid precursors via Pu.1- and Irf8-dependent pathways

22 June 2018

1 reference

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Microglia: scapegoat, saboteur, or something else?

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5482419

Stroma-derived interleukin-34 controls the development and maintenance of langerhans cells and the maintenance of microglia

22 June 2018

1 reference

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STAR: ultrafast universal RNA-seq aligner

22 June 2018

1 reference

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IL-34 is a tissue-restricted ligand of CSF1R required for the development of Langerhans cells and microglia

22 June 2018

1 reference

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The complement system: an unexpected role in synaptic pruning during development and disease

22 June 2018

1 reference

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A lineage of myeloid cells independent of Myb and hematopoietic stem cells

22 June 2018

1 reference

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Identification of oligomers at early stages of tau aggregation in Alzheimer's disease

22 June 2018

1 reference

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Heterogeneity of CNS myeloid cells and their roles in neurodegeneration

22 June 2018

1 reference

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RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome

22 June 2018

1 reference

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Synaptic pruning by microglia is necessary for normal brain development

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5482419

The transcription factor NR4A1 (Nur77) controls bone marrow differentiation and the survival of Ly6C- monocytes

22 June 2018

1 reference

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22 June 2018

Physiology of microglia

1 reference

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CX3CR1 in microglia regulates brain amyloid deposition through selective protofibrillar amyloid-β phagocytosis

22 June 2018

1 reference

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Fate mapping analysis reveals that adult microglia derive from primitive macrophages

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5482419

TGF-β and LPS modulate ADP-induced migration of microglial cells through P2Y1 and P2Y12 receptor expression

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5482419

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5482419

Microglial dysfunction and defective beta-amyloid clearance pathways in aging Alzheimer's disease mice

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5482419

Neuronal 'On' and 'Off' signals control microglia

22 June 2018

1 reference

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The origin and cell lineage of microglia: new concepts

22 June 2018

1 reference

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Development of the hemangioblast defines the onset of hematopoiesis in human ES cell differentiation cultures

22 June 2018

1 reference

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The P2Y12 receptor regulates microglial activation by extracellular nucleotides

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5482419

Inflammatory cytokine levels correlate with amyloid load in transgenic mouse models of Alzheimer's disease

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5482419

Colonisation of the developing human brain and spinal cord by microglia: a review

22 June 2018

1 reference

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Apoptosis is induced by beta-amyloid in cultured central nervous system neurons

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5482419

Interferon regulatory factor 1 is a myeloid differentiation primary response gene induced by interleukin 6 and leukemia inhibitory factor: role in growth inhibition

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5482419

ABCA7 Mediates Phagocytic Clearance of Amyloid-β in the Brain.

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5482419

Microglia development follows a stepwise program to regulate brain homeostasis.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5482419

C9orf72 is required for proper macrophage and microglial function in mice

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5482419

Alleviation of neurotoxicity by microglial human Siglec-11.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5482419

Invasion of hematopoietic cells into the brain of amyloid precursor protein transgenic mice.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5482419

Microglial phagocytosis induced by fibrillar beta-amyloid and IgGs are differentially regulated by proinflammatory cytokines.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5482419

Up-regulation of the inflammatory cytokines IFN-gamma and IL-12 and down-regulation of IL-4 in cerebral cortex regions of APP(SWE) transgenic mice.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5482419

Astrocyte-released cytokines induce ramification and outward K+ channel expression in microglia via distinct signalling pathways

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5482419

Quantitative characterization of crude synaptosomal fraction (P-2) components by flow cytometry

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5482419

Interleukin-1 beta and interleukin-6 are elevated in the cerebrospinal fluid of Alzheimer's and de novo Parkinson's disease patients.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5482419

TGF-β signaling through SMAD2/3 induces the quiescent microglial phenotype within the CNS environment

15 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28426964

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.NEURON.2017.03.042

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28426964%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28426964%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

1 reference