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Visualization of chemokine receptor activation in transgenic mice reveals peripheral activation of CCR2 receptors in states of neuropathic pain

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Expression of CCR2 in Both Resident and Bone Marrow-Derived Microglia Plays a Critical Role in Neuropathic Pain

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JNK-induced MCP-1 production in spinal cord astrocytes contributes to central sensitization and neuropathic pain

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Neuronal CC chemokines: the distinct roles of CCL21 and CCL2 in neuropathic pain

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Activation of CB2 cannabinoid receptors by AM1241 inhibits experimental neuropathic pain: pain inhibition by receptors not present in the CNS

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21 January 2018

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https://api.crossref.org/works/10.1038%2FNRD.2015.14

The role of matrix metalloproteinases in glioma invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Gliomas induce and exploit microglial MT1-MMP expression for tumor expansion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

The role of microglia and matrix metalloproteinases involvement in neuroinflammation and gliomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Microglial stimulation of glioblastoma invasion involves epidermal growth factor receptor (EGFR) and colony stimulating factor 1 receptor (CSF-1R) signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

A randomized, double-blind, placebo-controlled trial of a chemokine receptor 2 (CCR2) antagonist in posttraumatic neuralgia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Genetically determined P2X7 receptor pore formation regulates variability in chronic pain sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Efficacy and safety of CE-224,535, an antagonist of P2X7 receptor, in treatment of patients with rheumatoid arthritis inadequately controlled by methotrexate

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Pharmacokinetic and pharmacodynamic profiling of a P2X7 receptor allosteric modulator GSK1482160 in healthy human subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Pharmacology of a novel central nervous system-penetrant P2X7 antagonist JNJ-42253432.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Pharmacological characterization of a novel centrally permeable P2X7 receptor antagonist: JNJ-47965567.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

UDP acting at P2Y6 receptors is a mediator of microglial phagocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Immunotherapy for Alzheimer's disease: past, present and future

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Mechanism of amyloid removal in patients with Alzheimer disease treated with gantenerumab.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Immunotherapeutic approaches for Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

New developments of clinical trial in immunotherapy for Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Inhibition of Microglial Activation Attenuates the Development but Not Existing Hypersensitivity in a Rat Model of Neuropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Minocycline attenuates mechanical allodynia and proinflammatory cytokine expression in rat models of pain facilitation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Glial inhibitors influence the mRNA and protein levels of mGlu2/3, 5 and 7 receptors and potentiate the analgesic effects of their ligands in a mouse model of neuropathic pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

A novel mechanism of action of tetracyclines: effects on nitric oxide synthases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Minocycline inhibits caspase-1 and caspase-3 expression and delays mortality in a transgenic mouse model of Huntington disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Proteomic analysis of the anti-inflammatory action of minocycline

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Minocycline suppresses activation of nuclear factor of activated T cells 1 (NFAT1) in human CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Direct protection of cultured neurons from ischemia-like injury by minocycline.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Neuroprotection by minocycline caused by direct and specific scavenging of peroxynitrite

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

A novel target of action of minocycline in NGF-induced neurite outgrowth in PC12 cells: translation initiation [corrected] factor eIF4AI.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Minocycline protects SH-SY5Y cells from 6-hydroxydopamine by inhibiting both caspase-dependent and -independent programmed cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Minocycline delays photoreceptor death in the rds mouse through a microglia-independent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Minocycline does not inhibit microglia proliferation or neuronal regeneration in the facial nucleus following crush injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

ALS: focus on purinergic signalling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Targeting microglial purinergic signaling to improve morphine analgesia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Purinergic receptors in microglia: functional modal shifts of microglia mediated by P2 and P1 receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Expression of P2 nucleotide receptors varies with age and sex in murine brain microglia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Purinergic systems in microglia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Fractalkine/CX3CR1 signaling during neuropathic pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Microglial derived tumor necrosis factor-α drives Alzheimer's disease-related neuronal cell cycle events

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Opposing effects of membrane-anchored CX3CL1 on amyloid and tau pathologies via the p38 MAPK pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Modulating neurotoxicity through CX3CL1/CX3CR1 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Inflammatory findings on species extrapolations: humans are definitely no 70-kg mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Of mice and not men: differences between mouse and human immunology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Immune-cell lineage commitment: translation from mice to humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Genomic responses in mouse models poorly mimic human inflammatory diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Conservation and divergence in the transcriptional programs of the human and mouse immune systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

The human side of microglia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Regulation of CD14 expression on human adult central nervous system-derived microglia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Direct ex vivo flow cytometric analysis of human microglial cell CD4 expression: examination of central nervous system biopsy specimens from HIV-seropositive patients and patients with other neurological disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

The LPS receptor, CD14, in experimental autoimmune encephalomyelitis and multiple sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

CD14 is required for MyD88-independent LPS signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Phenotyping primary human microglia: tight regulation of LPS responsiveness.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Macrophage biology and immunology: man is not a mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Propentofylline, a CNS glial modulator does not decrease pain in post-herpetic neuralgia patients: in vitro evidence for differential responses in human and rodent microglia and macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Neural mechanisms of ageing and cognitive decline

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Review: microglia of the aged brain: primed to be activated and resistant to regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Microglia derived from aging mice exhibit an altered inflammatory profile.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Microglial priming in neurodegenerative disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Microglial activation and chronic neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Peripheral lipopolysaccharide (LPS) challenge promotes microglial hyperactivity in aged mice that is associated with exaggerated induction of both pro-inflammatory IL-1beta and anti-inflammatory IL-10 cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Lipopolysaccharide-induced interleukin (IL)-4 receptor-α expression and corresponding sensitivity to the M2 promoting effects of IL-4 are impaired in microglia of aged mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Systemic infections and inflammation affect chronic neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Human CNS immune senescence and neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Microglial senescence: does the brain's immune system have an expiration date?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Telomere dynamics in mice and humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

THE LIMITED IN VITRO LIFETIME OF HUMAN DIPLOID CELL STRAINS

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Telomere shortening is associated with cell division in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Cellular senescence: when bad things happen to good cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

21 January 2018

Telomeres and disease

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Progressive telomere shortening occurs in cultured rat microglia, but not astrocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

An optimized protocol for the acute isolation of human microglia from autopsy brain samples.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

A neurodegeneration-specific gene-expression signature of acutely isolated microglia from an amyotrophic lateral sclerosis mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Isolation of glia from Alzheimer's mice reveals inflammation and dysfunction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

The P2X7 receptor channel: recent developments and the use of P2X7 antagonists in models of disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Mammalian P2X7 receptor pharmacology: comparison of recombinant mouse, rat and human P2X7 receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Significance of P2X7 receptor variants to human health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

COX-2, CB2 and P2X7-immunoreactivities are increased in activated microglial cells/macrophages of multiple sclerosis and amyotrophic lateral sclerosis spinal cord

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Experimental autoimmune encephalomyelitis disrupts endocannabinoid-mediated neuroprotection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Immunization with a nontoxic/nonfibrillar amyloid-beta homologous peptide reduces Alzheimer's disease-associated pathology in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Autoantibodies against beta-amyloid are common in Alzheimer's disease and help control plaque burden.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Inflammatory components in human Alzheimer's disease and after active amyloid-β42 immunization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Microglial alterations in human Alzheimer's disease following Aβ42 immunization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Association of CD33 polymorphism rs3865444 with Alzheimer's disease pathology and CD33 expression in human cerebral cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

TREM2 is upregulated in amyloid plaque-associated microglia in aged APP23 transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Heterogeneous expression of the triggering receptor expressed on myeloid cells-2 on adult murine microglia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Microglial beclin 1 regulates retromer trafficking and phagocytosis and is impaired in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

TREM2 Protein Expression Changes Correlate with Alzheimer's Disease Neurodegenerative Pathologies in Post-Mortem Temporal Cortices

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Ccr2 deficiency impairs microglial accumulation and accelerates progression of Alzheimer-like disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

CC chemokine receptor 2 deficiency aggravates cognitive impairments and amyloid pathology in a transgenic mouse model of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

IKKβ deficiency in myeloid cells ameliorates Alzheimer's disease-related symptoms and pathology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Neuronal CCL21 up-regulates microglia P2X4 expression and initiates neuropathic pain development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Impaired neuropathic pain responses in mice lacking the chemokine receptor CCR2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Attenuation of rodent neuropathic pain by an orally active peptide, RAP-103, which potently blocks CCR2- and CCR5-mediated monocyte chemotaxis and inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Monocytes expressing CX3CR1 orchestrate the development of vincristine-induced pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Indoleamine 2,3-dioxygenase inhibition attenuates lipopolysaccharide induced persistent microglial activation and depressive-like complications in fractalkine receptor (CX(3)CR1)-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Interferon-gamma and tumor necrosis factor-alpha mediate the upregulation of indoleamine 2,3-dioxygenase and the induction of depressive-like behavior in mice in response to bacillus Calmette-Guerin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Decreased quinolinic acid in the hippocampus of depressive patients: evidence for local anti-inflammatory and neuroprotective responses?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Reduced microglial immunoreactivity for endogenous NMDA receptor agonist quinolinic acid in the hippocampus of schizophrenia patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

S100B promotes glioma growth through chemoattraction of myeloid-derived macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Effect of miR-142-3p on the M2 macrophage and therapeutic efficacy against murine glioblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Efficacy and safety studies of gantenerumab in patients with Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Clinical evaluation of the efficacy of the P2X7purinergic receptor antagonist AZD9056 on the signs and symptoms of rheumatoid arthritis in patients with active disease despite treatment with methotrexate or sulphasalazine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Monocytes P2X7 purinergic receptor is modulated by glatiramer acetate in multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

P2X7 Receptor Blockade Prevents ATP Excitotoxicity in Oligodendrocytes and Ameliorates Experimental Autoimmune Encephalomyelitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Commentary on Landry et al.: “Propentofylline, a CNS glial modulator, does not decrease pain in post-herpetic neuralgia patients: In vitro evidence for differential responses in human and rodent microglia and macrophages”

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Preclinical research: Make mouse studies work

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Microglia and neuroprotection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

P2X4 receptors of microglia in neuropathic pain

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Editorial to special issue: monocytes in homeostasis and disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Male donor-derived cells in the brains of female sex-mismatched bone marrow transplant recipients: a Y-chromosome specific in situ hybridization study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

A complex proinflammatory role for peripheral monocytes in Alzheimer's disease.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Tumor necrosis factor-alpha induces mechanical allodynia after spinal nerve ligation by activation of p38 MAPK in primary sensory neurons

31 March 2020

2 references

https://api.crossref.org/works/10.1038%2FNRD.2015.14

31 March 2020

12 December 2020

CB2 cannabinoid receptor-mediated peripheral antinociception

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Analysis of single nucleotide polymorphisms in genes in the chromosome 12Q24.31 region points to P2RX7 as a susceptibility gene to bipolar affective disorder

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

The activation of monocyte and T cell networks in patients with bipolar disorder

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Genentech's Alzheimer's antibody trial to study disease prevention

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Gantenerumab: a novel human anti-Aβ antibody demonstrates sustained cerebral amyloid-β binding and elicits cell-mediated removal of human amyloid-β

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Minocycline and pentoxifylline attenuate allodynia and hyperalgesia and potentiate the effects of morphine in rat and mouse models of neuropathic pain

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

TLR signaling tailors innate immune responses in human microglia and astrocytes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2015.14

Reduced inflammatory and neuropathic pain and decreased spinal microglial response in fractalkine receptor (CX3CR1) knockout mice

31 March 2020

1 reference

12 December 2020

Comparison of phenotypic and functional properties of immediately ex vivo and cultured human adult microglia.

1 reference

12 December 2020

Antibacterial activity in mice of minocycline, a new tetracycline

1 reference

12 December 2020

The heterogeneity of mononuclear phagocytes in lymphoid organs: distinct macrophage subpopulations in the rat recognized by monoclonal antibodies ED1, ED2 and ED3.

1 reference

12 December 2020

Minocycline inhibits the production of inducible nitric oxide synthase in articular chondrocytes

1 reference

12 December 2020

Expression of purinergic P2X7 receptor in rat brain during the symptomatic phase of experimental autoimmune encephalomyelitis and after recovery of neurological deficits

1 reference

12 December 2020

SOCS, inflammation, and cancer

1 reference

12 December 2020

Microglia and macrophages in malignant gliomas: recent discoveries and implications for promising therapies

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRD.2015.14

1 reference

5 September 2017

1 reference