Effects of palmitate on ER and cytosolic Ca2+ homeostasis in beta-cells (Q46164585)

20 December 2017

title

Effects of palmitate on ER and cytosolic Ca2+ homeostasis in beta-cells (English)

1 reference

20 December 2017

author name string

Kamila S Gwiazda

1

1 reference

20 December 2017

Ting-Lin B Yang

2

1 reference

20 December 2017

Yalin Lin

3

1 reference

20 December 2017

James D Johnson

4

1 reference

20 December 2017

publication date

13 January 2009

1 reference

20 December 2017

American Journal of Physiology - Endocrinology and Metabolism

published in

1 reference

20 December 2017

volume

296

1 reference

20 December 2017

page(s)

E690-701

1 reference

20 December 2017

issue

4

1 reference

20 December 2017

Stimulation of islet protein kinase C translocation by palmitate requires metabolism of the fatty acid.

cites work

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90525.2008

Inhibition of Raf-1 alters multiple downstream pathways to induce pancreatic beta-cell apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90525.2008

The orphan G protein-coupled receptor GPR40 is activated by medium and long chain fatty acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90525.2008

Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90525.2008

Cytokines downregulate the sarcoendoplasmic reticulum pump Ca2+ ATPase 2b and deplete endoplasmic reticulum Ca2+, leading to induction of endoplasmic reticulum stress in pancreatic beta-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90525.2008

Involvement of Ca2+-mediated apoptotic signals in palmitate-induced MIN6N8a beta cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90525.2008

Fatty acid distribution in systems modeling the normal and diabetic human circulation. A 13C nuclear magnetic resonance study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90525.2008

Selective inhibition of eukaryotic translation initiation factor 2 alpha dephosphorylation potentiates fatty acid-induced endoplasmic reticulum stress and causes pancreatic beta-cell dysfunction and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90525.2008

Stimulation of insulin secretion by infusion of free fatty acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90525.2008

Initiation and execution of lipotoxic ER stress in pancreatic beta-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90525.2008

Acute stimulation with long chain acyl-CoA enhances exocytosis in insulin-secreting cells (HIT T-15 and NMRI beta-cells).

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90525.2008

Mechanisms involved in the cytotoxic and cytoprotective actions of saturated versus monounsaturated long-chain fatty acids in pancreatic beta-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90525.2008

Inflammatory mediators and islet beta-cell failure: a link between type 1 and type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90525.2008

Notch signalling suppresses apoptosis in adult human and mouse pancreatic islet cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90525.2008

Different role of saturated and unsaturated fatty acids in beta-cell apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90525.2008

The role for endoplasmic reticulum stress in diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90525.2008

GPR40 is expressed in glucagon producing cells and affects glucagon secretion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90525.2008

Oleic acid interacts with GPR40 to induce Ca2+ signaling in rat islet beta-cells: mediation by PLC and L-type Ca2+ channel and link to insulin release

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90525.2008

Comparison of the effect of individual saturated and unsaturated fatty acids on cell growth and death induction in the human pancreatic beta-cell line NES2Y.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90525.2008

Endoplasmic reticulum Ca2+ is important for the proteolytic processing and intracellular transport of proinsulin in the pancreatic beta-cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90525.2008

Free fatty acids regulate insulin secretion from pancreatic beta cells through GPR40.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90525.2008

Carboxypeptidase E mediates palmitate-induced beta-cell ER stress and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90525.2008

Increased islet apoptosis in Pdx1+/- mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90525.2008

Nicotinic acid-adenine dinucleotide phosphate-sensitive calcium stores initiate insulin signaling in human beta cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90525.2008

Chronic palmitate but not oleate exposure induces endoplasmic reticulum stress, which may contribute to INS-1 pancreatic beta-cell apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90525.2008

Free fatty acids and cytokines induce pancreatic beta-cell apoptosis by different mechanisms: role of nuclear factor-kappaB and endoplasmic reticulum stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90525.2008

Differences in glucose recognition by individual rat pancreatic B cells are associated with intercellular differences in glucose-induced biosynthetic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90525.2008

A human cell surface receptor activated by free fatty acids and thiazolidinedione drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90525.2008

Differential activation of ER stress and apoptosis in response to chronically elevated free fatty acids in pancreatic beta-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90525.2008

Endoplasmic reticulum stress contributes to beta cell apoptosis in type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90525.2008

Roles of IP3R and RyR Ca2+ channels in endoplasmic reticulum stress and beta-cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90525.2008

Acute effects of insulin on beta-cells from transplantable human islets

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90525.2008

Prolonged exposure to free fatty acids has cytostatic and pro-apoptotic effects on human pancreatic islets: evidence that beta-cell death is caspase mediated, partially dependent on ceramide pathway, and Bcl-2 regulated.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90525.2008

Monounsaturated fatty acids prevent the deleterious effects of palmitate and high glucose on human pancreatic beta-cell turnover and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90525.2008

Distinct effects of saturated and monounsaturated fatty acids on beta-cell turnover and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90525.2008

The endoplasmic reticulum in pancreatic beta cells of type 2 diabetes patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90525.2008

Establishment of a pancreatic beta cell line that retains glucose-inducible insulin secretion: special reference to expression of glucose transporter isoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90525.2008

Fatty acid signaling in the beta-cell and insulin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90525.2008

Palmitate increases L-type Ca2+ currents and the size of the readily releasable granule pool in mouse pancreatic beta-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90525.2008

Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90525.2008

Ca2+ indicators based on computationally redesigned calmodulin-peptide pairs

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90525.2008

Bcl-2-mediated alterations in endoplasmic reticulum Ca2+ analyzed with an improved genetically encoded fluorescent sensor

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90525.2008

Measuring calcium signaling using genetically targetable fluorescent indicators

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90525.2008

Palmitate potentiation of glucose-induced insulin release: a study using 2-bromopalmitate

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90525.2008

Chronic exposure to free fatty acids or high glucose induces apoptosis in rat pancreatic islets: possible role of oxidative stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90525.2008

Palmitate-induced Ca2+-signaling in pancreatic beta-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90525.2008

Use of analogs and inhibitors to study the functional significance of protein palmitoylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90525.2008

Interactions of long-chain fatty acids and albumin: determination of free fatty acid levels using the fluorescent probe ADIFAB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90525.2008

Reduced beta-cell mass and expression of oxidative stress-related DNA damage in the islet of Japanese Type II diabetic patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90525.2008

Free fatty acid receptor 1 (FFA(1)R/GPR40) and its involvement in fatty-acid-stimulated insulin secretion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90525.2008

Free fatty acids increase cytosolic free calcium and stimulate insulin secretion from beta-cells through activation of GPR40.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90525.2008

The mammalian unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90525.2008

Fatty acid-induced beta cell apoptosis: a link between obesity and diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90525.2008

Letter: Fatty acids, platelets, and microcirculatory obstruction

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90525.2008

Differential modulation of L-type calcium channel subunits by oleate

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90525.2008

Mechanisms of the stimulation of insulin release by saturated fatty acids. A study of palmitate effects in mouse beta-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90525.2008

Unbound rather than total concentration and saturation rather than unsaturation determine the potency of fatty acids on insulin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90525.2008

Endoplasmic reticulum stress: cell life and death decisions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90525.2008

Long-term exposure of rat pancreatic islets to fatty acids inhibits glucose-induced insulin secretion and biosynthesis through a glucose fatty acid cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90525.2008

Selective β-Cell Loss and α-Cell Expansion in Patients with Type 2 Diabetes Mellitus in Korea

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90525.2008

10.1152/AJPENDO.90525.2008

21 January 2018

Identifiers

DOI

1 reference

20 December 2017

PubMed ID

19141690

1 reference

20 December 2017