Dll4 and Notch signalling couples sprouting angiogenesis and artery formation (Q46340126)

21 December 2017

http://europepmc.org/abstract/MED/28714968

title

Dll4 and Notch signalling couples sprouting angiogenesis and artery formation (English)

1 reference

21 December 2017

http://europepmc.org/abstract/MED/28714968

author

Ralf H Adams

16

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5 June 2020

Urs H Langen

11

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5 June 2020

14

Napoleone Ferrara

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5 June 2020

author name string

Mara E Pitulescu

1

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5 June 2020

Inga Schmidt

2

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5 June 2020

Benedetto Daniele Giaimo

3

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5 June 2020

Tobiah Antoine

4

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5 June 2020

Frank Berkenfeld

5

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5 June 2020

Francesca Ferrante

6

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5 June 2020

Hongryeol Park

7

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5 June 2020

Manuel Ehling

8

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5 June 2020

Daniel Biljes

9

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5 June 2020

Susana F Rocha

10

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5 June 2020

Martin Stehling

12

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5 June 2020

Takashi Nagasawa

13

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5 June 2020

Tilman Borggrefe

15

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5 June 2020

publication date

17 July 2017

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21 December 2017

http://europepmc.org/abstract/MED/28714968

published in

Nature Cell Biology

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5 June 2020

volume

19

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5 June 2020

issue

8

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5 June 2020

page(s)

915-927

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The biology of VEGF and its receptors

5 June 2020

cites work

1 reference

Delta-like ligand 4 (Dll4) is induced by VEGF as a negative regulator of angiogenic sprouting

21 January 2018

1 reference

Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis

21 January 2018

1 reference

VEGFR3 does not sustain retinal angiogenesis without VEGFR2

21 January 2018

1 reference

The Notch ligand Delta-like 4 negatively regulates endothelial tip cell formation and vessel branching.

21 January 2018

1 reference

Endothelial cells dynamically compete for the tip cell position during angiogenic sprouting

21 January 2018

1 reference

Notch-dependent VEGFR3 upregulation allows angiogenesis without VEGF-VEGFR2 signalling

21 January 2018

1 reference

Notch signalling limits angiogenic cell behaviour in developing zebrafish arteries

21 January 2018

1 reference

Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation

21 January 2018

1 reference

The notch ligands Dll4 and Jagged1 have opposing effects on angiogenesis

21 January 2018

1 reference

Endothelial Jagged1 antagonizes Dll4 regulation of endothelial branching and promotes vascular maturation downstream of Dll4/Notch1.

21 January 2018

1 reference

NOTCH decoys that selectively block DLL/NOTCH or JAG/NOTCH disrupt angiogenesis by unique mechanisms to inhibit tumor growth

21 January 2018

1 reference

Angiogenic morphogenesis driven by dynamic and heterogeneous collective endothelial cell movement.

21 January 2018

1 reference

Tipping the balance: robustness of tip cell selection, migration and fusion in angiogenesis

21 January 2018

1 reference

The role of differential VE-cadherin dynamics in cell rearrangement during angiogenesis.

21 January 2018

1 reference

Tip cell overtaking occurs as a side effect of sprouting in computational models of angiogenesis.

21 January 2018

1 reference

DLL1-mediated Notch activation regulates endothelial identity in mouse fetal arteries

21 January 2018

1 reference

Extrinsic Notch ligand Delta-like 1 regulates tip cell selection and vascular branching morphogenesis

21 January 2018

1 reference

The chemokine receptor CXCR4 is essential for vascularization of the gastrointestinal tract

21 January 2018

1 reference

The role of CXCL12 in the organ-specific process of artery formation

21 January 2018

1 reference

Divergent angiocrine signals from vascular niche balance liver regeneration and fibrosis.

21 January 2018

1 reference

Microarray analysis of retinal endothelial tip cells identifies CXCR4 as a mediator of tip cell morphology and branching

21 January 2018

1 reference

SDF-1/CXCR4 contributes to the activation of tip cells and microglia in retinal angiogenesis

21 January 2018

1 reference

Autocrine VEGF signaling is required for vascular homeostasis

21 January 2018

1 reference

Autocrine VEGF maintains endothelial survival through regulation of metabolism and autophagy

21 January 2018

1 reference

Crim1 maintains retinal vascular stability during development by regulating endothelial cell Vegfa autocrine signaling.

21 January 2018

1 reference

Identification and functional analysis of endothelial tip cell-enriched genes

21 January 2018

1 reference

Esm1 modulates endothelial tip cell behavior and vascular permeability by enhancing VEGF bioavailability.

21 January 2018

1 reference

Notch-independent RBPJ controls angiogenesis in the adult heart

21 January 2018

1 reference

Notch activation during endothelial cell network formation in vitro targets the basic HLH transcription factor HESR-1 and downregulates VEGFR-2/KDR expression

21 January 2018

1 reference

Up-regulation of the Notch ligand Delta-like 4 inhibits VEGF-induced endothelial cell function

21 January 2018

1 reference

Regulation of multiple angiogenic pathways by Dll4 and Notch in human umbilical vein endothelial cells

21 January 2018

1 reference

Crosstalk between vascular endothelial growth factor, notch, and transforming growth factor-beta in vascular morphogenesis

21 January 2018

1 reference

Notch controls retinal blood vessel maturation and quiescence.

21 January 2018

1 reference

Genetic targeting of sprouting angiogenesis using Apln-CreER.

21 January 2018

1 reference

A global double-fluorescent Cre reporter mouse

21 January 2018

1 reference

Arteries are formed by vein-derived endothelial tip cells

21 January 2018

1 reference

Lineage tracing reveals Lgr5+ stem cell activity in mouse intestinal adenomas

21 January 2018

1 reference

Inhibition of Dll4 signalling inhibits tumour growth by deregulating angiogenesis

21 January 2018

1 reference

Notch signaling controls multiple steps of pancreatic differentiation

21 January 2018

1 reference

Monitoring Notch1 activity in development: evidence for a feedback regulatory loop

21 January 2018

1 reference

A bright single-cell resolution live imaging reporter of Notch signaling in the mouse.

21 January 2018

1 reference

Faithful activation of an extra-bright red fluorescent protein in "knock-in" Cre-reporter mice ideally suited for lineage tracing studies.

21 January 2018

1 reference

Gridlock signalling pathway fashions the first embryonic artery

21 January 2018

1 reference

Dosage-sensitive requirement for mouse Dll4 in artery development

21 January 2018

1 reference

Endothelial expression of constitutively active Notch4 elicits reversible arteriovenous malformations in adult mice

21 January 2018

1 reference

Genome-wide analysis reveals conserved and divergent features of Notch1/RBPJ binding in human and murine T-lymphoblastic leukemia cells

21 January 2018

1 reference

Histone demethylase KDM5A is an integral part of the core Notch-RBP-J repressor complex

21 January 2018

1 reference

Notch ligand Delta-like 1 is essential for postnatal arteriogenesis.

21 January 2018

1 reference

Deletion of Rbpj from postnatal endothelium leads to abnormal arteriovenous shunting in mice.

21 January 2018

1 reference

Delta-like 4 is the essential, nonredundant ligand for Notch1 during thymic T cell lineage commitment.

21 January 2018

1 reference

Efficient, inducible Cre-recombinase activation in vascular endothelium.

21 January 2018

1 reference

Inducible gene targeting in the neonatal vasculature and analysis of retinal angiogenesis in mice

21 January 2018

1 reference

Delta-like 1 is necessary for the generation of marginal zone B cells but not T cells in vivo

21 January 2018

1 reference

Cortical and retinal defects caused by dosage-dependent reductions in VEGF-A paracrine signaling

21 January 2018

1 reference

Cellular niches controlling B lymphocyte behavior within bone marrow during development.

21 January 2018

1 reference

Ephrin-B2 controls VEGF-induced angiogenesis and lymphangiogenesis

21 January 2018

1 reference

Rapid bacterial artificial chromosome modification for large-scale mouse transgenesis

21 January 2018

1 reference

Notch ligands with contrasting functions: Jagged1 and Delta1 in the mouse inner ear

21 January 2018

1 reference

Notch activation induces apoptosis in neural progenitor cells through a p53-dependent pathway

21 January 2018

1 reference

A phospho-dependent mechanism involving NCoR and KMT2D controls a permissive chromatin state at Notch target genes.

21 January 2018

1 reference

Signal transduction by vascular endothelial growth factor receptors

21 January 2018

1 reference

7 January 2021

Agent-based simulation of notch-mediated tip cell selection in angiogenic sprout initialisation

1 reference

7 January 2021

Development of retinal vasculature is mediated by hypoxia-induced vascular endothelial growth factor (VEGF) expression by neuroglia

1 reference

7 January 2021

Hypoxia regulates the expression of vascular permeability factor/vascular endothelial growth factor (VPF/VEGF) and its receptors in human skin

1 reference

7 January 2021

Inducible gene knockout of transcription factor recombination signal binding protein-J reveals its essential role in T versus B lineage decision

1 reference

7 January 2021

Endothelial Notch signalling limits angiogenesis via control of artery formation.

1 reference

7 January 2021

Deletion of the selection cassette, but not cis-acting elements, in targeted Flk1-lacZ allele reveals Flk1 expression in multipotent mesodermal progenitors

1 reference

7 January 2021

Notch signaling is required for arterial-venous differentiation during embryonic vascular development.

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28714968

12 December 2020

inferred from PubMed ID database lookup

Notch signaling is essential for vascular morphogenesis in mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28714968

12 December 2020

inferred from PubMed ID database lookup

VEGF is required for growth and survival in neonatal mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28714968

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/NCB3555

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28714968%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

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