Deletion of the ageing gene p66(Shc) reduces early stroke size following ischaemia/reperfusion brain injury (Q47282946)

13 January 2018

title

Deletion of the ageing gene p66(Shc) reduces early stroke size following ischaemia/reperfusion brain injury (English)

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13 January 2018

author

Ghazaleh Tabatabai

8

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13 January 2018

Francesco Cosentino

10

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13 January 2018

Thomas Lüscher

14

object named as

Thomas F Lüscher

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13 January 2018

12

Michael Weller

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13 January 2018

Remo D Spescha

1

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13 January 2018

Yi Shi

2

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13 January 2018

Susanne Wegener

3

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13 January 2018

Stephan Keller

4

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13 January 2018

Bruno Weber

5

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13 January 2018

Matthias M Wyss

6

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13 January 2018

Nadine Lauinger

7

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Francesco Paneni

9

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Christoph Hock

11

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Roger M Nitsch

13

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Giovanni G Camici

15

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publication date

24 September 2012

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published in

European Heart Journal

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13 January 2018

volume

34

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page(s)

96-103

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issue

2

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Stroke epidemiology in the developing world

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Decreased levels of plasma vitamin C and increased concentrations of inflammatory and oxidative stress markers after stroke

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Inhibition of NADPH oxidase is neuroprotective after ischemia-reperfusion

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Oxidized low-density lipoprotein activates p66Shc via lectin-like oxidized low-density lipoprotein receptor-1, protein kinase C-beta, and c-Jun N-terminal kinase kinase in human endothelial cells

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p66Shc deletion confers vascular protection in advanced atherosclerosis in hypercholesterolemic apolipoprotein E knockout mice

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Genetic deletion of p66(Shc) adaptor protein prevents hyperglycemia-induced endothelial dysfunction and oxidative stress.

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p66Shc-generated oxidative signal promotes fat accumulation

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Inhibition of p66ShcA longevity gene rescues podocytes from HIV-1-induced oxidative stress and apoptosis

21 January 2018

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The cardioprotective effects elicited by p66(Shc) ablation demonstrate the crucial role of mitochondrial ROS formation in ischemia/reperfusion injury

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Expression and activation of SH2/PTB-containing ShcA adaptor protein reflects the pattern of neurogenesis in the mammalian brain

21 January 2018

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Essential role of the redox-sensitive kinase p66shc in determining energetic and oxidative status and cell fate in neuronal preconditioning

21 January 2018

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Deletion of p66shc gene protects against age-related endothelial dysfunction

21 January 2018

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21 January 2018

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21 January 2018

Identifiers

DOI

10.1093/EURHEARTJ/EHS331

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13 January 2018

PubMed ID

23008506

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13 January 2018