Presenilin-1-dependent transcriptome changes. (Q49063888)

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8 January 2020

title

Presenilin-1-dependent transcriptome changes (English)

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1

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8 January 2020

Nina F. Schor

10

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8 January 2020

author name string

Zeljka Korade

2

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8 January 2020

Dominique Arion

3

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Orly Lazarov

4

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8 January 2020

Travis Unger

5

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8 January 2020

Melissa Macioce

6

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8 January 2020

Michael Sabatini

7

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David Terrano

8

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Katherine C Douglass

9

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8 January 2020

Sangram S Sisodia

11

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language of work or name

English

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publication date

1 February 2005

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8 January 2020

published in

Journal of Neuroscience

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volume

25

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issue

6

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8 January 2020

page(s)

1571-1578

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Identification of beta-amyloid-responsive genes by RNA differential display: early induction of a DNA damage-inducible gene, gadd45.

8 January 2020

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Presenilin-1 regulates intracellular trafficking and cell surface delivery of beta-amyloid precursor protein

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Experience-dependent coincident expression of the effector immediate-early genes arc and Homer 1a in hippocampal and neocortical neuronal networks

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Amyloid beta plaque-associated proteins C1q and SAP enhance the Abeta1-42 peptide-induced cytokine secretion by adult human microglia in vitro.

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Local synthesis of proteins at synaptic sites on dendrites: role in synaptic plasticity and memory consolidation?

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C1q-calreticulin induced oxidative neurotoxicity: relevance for the neuropathogenesis of Alzheimer's disease.

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Learning-induced arg 3.1/arc mRNA expression in the mouse brain

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Defects in expression of genes related to synaptic vesicle trafficking in frontal cortex of Alzheimer's disease

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Aph-1, Pen-2, and Nicastrin with Presenilin generate an active gamma-Secretase complex

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Amyloid, Presenilins, and Alzheimer’s Disease

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Selectively reduced expression of synaptic plasticity-related genes in amyloid precursor protein + presenilin-1 transgenic mice.

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DNA microarray profiling of developing PS1-deficient mouse brain reveals complex and coregulated expression changes

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cDNA microarray and proteomic approaches in the study of brain diseases: focus on schizophrenia and Alzheimer's disease

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Identification of Cathepsin B as a Mediator of Neuronal Death Induced by Aβ-activated Microglial Cells Using a Functional Genomics Approach

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Amyloid suppresses induction of genes critical for memory consolidation in APP + PS1 transgenic mice.

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Molecular hierarchy in neurons differentiated from mouse ES cells containing a single human chromosome 21.

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12 December 2020

Amino- and carboxyl-terminal mutants of presenilin 1 cause neuronal cell death through distinct toxic mechanisms: Study of 27 different presenilin 1 mutants

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Neuronal localization of C1q in preclinical Alzheimer's disease

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Incipient Alzheimer's disease: microarray correlation analyses reveal major transcriptional and tumor suppressor responses

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Expression of nitric oxide system in clinically evaluated cases of Alzheimer's disease.

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Loss of presenilin function causes impairments of memory and synaptic plasticity followed by age-dependent neurodegeneration

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c-fos protein-like immunoreactivity: distribution in the human brain and over-expression in the hippocampus of patients with Alzheimer's disease

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12 December 2020

Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene

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Increased immunoreactivity for Jun- and Fos-related proteins in Alzheimer's disease: association with pathology

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12 December 2020

Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

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12 December 2020

Activation of c-Fos contributes to amyloid beta-peptide-induced neurotoxicity

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12 December 2020

Endoproteolysis of presenilin 1 and accumulation of processed derivatives in vivo

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12 December 2020

Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1

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12 December 2020

Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo

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12 December 2020

Hyperaccumulation of FAD-linked presenilin 1 variants in vivo

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10.1523/JNEUROSCI.4145-04.2005

Identifiers

DOI

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8 January 2020

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8 January 2020

PubMed publication ID

15703411

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