The Aggregation Free Energy Landscapes of Polyglutamine Repeats (Q49318824)

20 February 2018

title

The Aggregation Free Energy Landscapes of Polyglutamine Repeats (English)

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20 February 2018

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1

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20 February 2018

Peter Guy Wolynes

series ordinal

4

object named as

Peter G Wolynes

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20 February 2018

3

Weihua Zheng

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20 February 2018

MinYeh Tsai

2

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20 February 2018

language of work or name

English

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publication date

27 October 2016

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20 February 2018

Journal of the American Chemical Society

published in

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20 February 2018

volume

138

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20 February 2018

issue

46

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20 February 2018

page(s)

15197-15203

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20 February 2018

Exploring the aggregation free energy landscape of the amyloid-β protein (1-40).

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Biophysical underpinnings of the repeat length dependence of polyglutamine amyloid formation

22 May 2018

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Structural motif of polyglutamine amyloid fibrils discerned with mixed-isotope infrared spectroscopy.

22 May 2018

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Free energy landscapes for initiation and branching of protein aggregation

22 May 2018

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Unmasking the roles of N- and C-terminal flanking sequences from exon 1 of huntingtin as modulators of polyglutamine aggregation

22 May 2018

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β-hairpin-mediated nucleation of polyglutamine amyloid formation.

22 May 2018

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Frustration in the energy landscapes of multidomain protein misfolding

22 May 2018

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Three-dimensional structures self-assembled from DNA bricks

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Physical chemistry of polyglutamine: intriguing tales of a monotonous sequence

22 May 2018

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Aggregation kinetics of interrupted polyglutamine peptides

22 May 2018

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Role of water in protein aggregation and amyloid polymorphism

22 May 2018

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Critical nucleus size for disease-related polyglutamine aggregation is repeat-length dependent

22 May 2018

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Tracking mutant huntingtin aggregation kinetics in cells reveals three major populations that include an invariant oligomer pool.

22 May 2018

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Mutant huntingtin fragments form oligomers in a polyglutamine length-dependent manner in vitro and in vivo

22 May 2018

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Secondary Structure of Huntingtin Amino-Terminal Region

22 May 2018

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Examining polyglutamine peptide length: a connection between collapsed conformations and increased aggregation

22 May 2018

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22 May 2018

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polyglutamine aggregation nucleation: thermodynamics of a highly unfavorable protein folding reaction

22 May 2018

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Amyloid-like fibrils of ribonuclease A with three-dimensional domain-swapped and native-like structure.

22 May 2018

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Structure of the cross-beta spine of amyloid-like fibrils

22 May 2018

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Mutational analysis of the structural organization of polyglutamine aggregates

22 May 2018

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Huntington's disease age-of-onset linked to polyglutamine aggregation nucleation

22 May 2018

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Amyloid fibers are water-filled nanotubes

22 May 2018

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Glutamine repeats and neurodegeneration

22 May 2018

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Funnels, pathways, and the energy landscape of protein folding: a synthesis

22 May 2018

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Prefibrillar huntingtin oligomers isolated from HD brain potently seed amyloid formation.

22 May 2018

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Structural characterization of polyglutamine fibrils by solid-state NMR spectroscopy

14 August 2018

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Effects of chain length on the aggregation of model polyglutamine peptides: molecular dynamics simulations

14 August 2018

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Oligoproline effects on polyglutamine conformation and aggregation

14 August 2018

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Characterizing the conformational ensemble of monomeric polyglutamine.

14 August 2018

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Solution structure of polyglutamine tracts in GST-polyglutamine fusion proteins

14 August 2018

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Polyglutamine aggregation behavior in vitro supports a recruitment mechanism of cytotoxicity

14 August 2018

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Assessing polyglutamine conformation in the nucleating event by molecular dynamics simulations

14 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27786478

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1021/JACS.6B08665

1 reference

20 February 2018

PMC publication ID

5803750

1 reference

20 February 2018

PubMed publication ID

27786478

1 reference

20 February 2018