Antiviral TRIMs: friend or foe in autoimmune and autoinflammatory disease? (Q50513813)

14 March 2018

title

Antiviral TRIMs: friend or foe in autoimmune and autoinflammatory disease? (English)

1 reference

14 March 2018

Claire Wynne

2

0 references

author name string

Caroline Jefferies

series ordinal

1

1 reference

14 March 2018

Rowan Higgs

series ordinal

3

1 reference

14 March 2018

publication date

25 August 2011

1 reference

14 March 2018

Nature Reviews Immunology

published in

1 reference

14 March 2018

volume

11

1 reference

14 March 2018

page(s)

617-625

1 reference

14 March 2018

issue

9

1 reference

14 March 2018

TRIM family proteins and their emerging roles in innate immunity

cites work

1 reference

The cytoplasmic body component TRIM5alpha restricts HIV-1 infection in Old World monkeys

21 January 2018

1 reference

Tripartite motif-containing 22 inhibits the activity of hepatitis B virus core promoter, which is dependent on nuclear-located RING domain

21 January 2018

1 reference

KAP1 controls endogenous retroviruses in embryonic stem cells

21 January 2018

1 reference

Tripartite-motif proteins and innate immune regulation

21 January 2018

1 reference

Antibodies to polynucleotides in human sera: antigenic specificity and relation to disease

21 January 2018

1 reference

Gout-associated uric acid crystals activate the NALP3 inflammasome

21 January 2018

1 reference

Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes

21 January 2018

1 reference

The NLRP3 inflammasome: a sensor for metabolic danger?

21 January 2018

1 reference

Type I interferon in systemic lupus erythematosus and other autoimmune diseases

21 January 2018

1 reference

Plasmacytoid dendritic cells: sensing nucleic acids in viral infection and autoimmune diseases.

21 January 2018

1 reference

A compass that points to lupus: genetic studies on type I interferon pathway.

21 January 2018

1 reference

Nucleic acid recognition by the innate immune system

21 January 2018

1 reference

RNA-associated autoantigens activate B cells by combined B cell antigen receptor/Toll-like receptor 7 engagement.

21 January 2018

1 reference

Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors

21 January 2018

1 reference

Cia5d regulates a new fibroblast-like synoviocyte invasion-associated gene expression signature.

21 January 2018

1 reference

Human TRIM gene expression in response to interferons

21 January 2018

1 reference

Type I interferon-dependent and -independent expression of tripartite motif proteins in immune cells.

21 January 2018

1 reference

Fine specificity of the autoimmune response to the Ro/SSA and La/SSB ribonucleoproteins

21 January 2018

1 reference

Cutting edge: autoantigen Ro52 is an interferon inducible E3 ligase that ubiquitinates IRF-8 and enhances cytokine expression in macrophages

21 January 2018

1 reference

The E3 ubiquitin ligase Ro52 negatively regulates IFN-beta production post-pathogen recognition by polyubiquitin-mediated degradation of IRF3

21 January 2018

1 reference

TRIM21 is essential to sustain IFN regulatory factor 3 activation during antiviral response

21 January 2018

1 reference

Fas-associated death domain (FADD) and the E3 ubiquitin-protein ligase TRIM21 interact to negatively regulate virus-induced interferon production

21 January 2018

1 reference

Loss of the lupus autoantigen Ro52/Trim21 induces tissue inflammation and systemic autoimmunity by disregulating the IL-23-Th17 pathway

21 January 2018

1 reference

Gene disruption study reveals a nonredundant role for TRIM21/Ro52 in NF-kappaB-dependent cytokine expression in fibroblasts

21 January 2018

1 reference

Self protection from anti-viral responses--Ro52 promotes degradation of the transcription factor IRF7 downstream of the viral Toll-Like receptors

21 January 2018

1 reference

Comment on "Gene disruption study reveals a nonredundant role for TRIM21/Ro52 in NF-kappa B-dependent cytokine expression in fibroblasts".

21 January 2018

1 reference

Antibodies mediate intracellular immunity through tripartite motif-containing 21 (TRIM21)

21 January 2018

1 reference

The estrogen-responsive B box protein: a novel regulator of keratinocyte differentiation

21 January 2018

1 reference

The estrogen-responsive B box protein is a novel regulator of the retinoid signal

21 January 2018

1 reference

TRIM16 acts as a tumour suppressor by inhibitory effects on cytoplasmic vimentin and nuclear E2F1 in neuroblastoma cells

21 January 2018

1 reference

Rheumatoid arthritis specific anti-Sa antibodies target citrullinated vimentin

21 January 2018

1 reference

The relevance of citrullinated vimentin in the production of antibodies against citrullinated proteins and the pathogenesis of rheumatoid arthritis

21 January 2018

1 reference

Diagnostic value of antibodies against a modified citrullinated vimentin in rheumatoid arthritis

21 January 2018

1 reference

Vimentin is secreted by activated macrophages

21 January 2018

1 reference

Infections and autoimmunity--friends or foes?

21 January 2018

1 reference

TRIM E3 ligases interfere with early and late stages of the retroviral life cycle

21 January 2018

1 reference

Implication of human endogenous retroviruses in the development of autoimmune diseases

21 January 2018

1 reference

TLR-mediated up-regulation of serum retroviral gp70 is controlled by the Sgp loci of lupus-prone mice

21 January 2018

1 reference

Role of endogenous retroviruses in murine SLE.

21 January 2018

1 reference

21 January 2018

1 reference

TRIM5alpha selectively binds a restriction-sensitive retroviral capsid

21 January 2018

1 reference

The etiology of multiple sclerosis: genetic evidence for the involvement of the human endogenous retrovirus HERV-Fc1

21 January 2018

1 reference

TRIM28 mediates primer binding site-targeted silencing of murine leukemia virus in embryonic cells

21 January 2018

1 reference

Embryonic stem cells use ZFP809 to silence retroviral DNAs

21 January 2018

1 reference

TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity

21 January 2018

1 reference

Reconstitution of the RIG-I pathway reveals a signaling role of unanchored polyubiquitin chains in innate immunity

21 January 2018

1 reference

Caspase-12 controls West Nile virus infection via the viral RNA receptor RIG-I.

21 January 2018

1 reference

The ubiquitin ligase TRIM56 regulates innate immune responses to intracellular double-stranded DNA

21 January 2018

1 reference

The genetics of autoimmune diseases: a networked perspective

21 January 2018

1 reference

TRIM40 promotes neddylation of IKKγ and is downregulated in gastrointestinal cancers

21 January 2018

1 reference

Polyubiquitin conjugation to NEMO by triparite motif protein 23 (TRIM23) is critical in antiviral defense

21 January 2018

1 reference

Identification of TRIM23 as a cofactor involved in the regulation of NF-kappaB by human cytomegalovirus

21 January 2018

1 reference

Impaired development of CD4+ CD25+ regulatory T cells in the absence of STAT1: increased susceptibility to autoimmune disease

21 January 2018

1 reference

Loss of T-bet, but not STAT1, prevents the development of experimental autoimmune encephalomyelitis

21 January 2018

1 reference

Polymorphisms in the tyrosine kinase 2 and interferon regulatory factor 5 genes are associated with systemic lupus erythematosus

21 January 2018

1 reference

A common haplotype of interferon regulatory factor 5 (IRF5) regulates splicing and expression and is associated with increased risk of systemic lupus erythematosus

21 January 2018

1 reference

Genetic variation at the IRF7/PHRF1 locus is associated with autoantibody profile and serum interferon-alpha activity in lupus patients

21 January 2018

1 reference

Physical and functional interactions between STAT3 and KAP1.

21 January 2018

1 reference

Ro52-mediated monoubiquitination of IKK{beta} down-regulates NF-{kappa}B signalling

21 January 2018

1 reference

Downregulation of active IKK beta by Ro52-mediated autophagy

21 January 2018

1 reference

PML and PML nuclear bodies: implications in antiviral defence

21 January 2018

1 reference

PML positively regulates interferon gamma signaling

21 January 2018

1 reference

The promyelocytic leukemia protein represses A20-mediated transcription

21 January 2018

1 reference

Promyelocytic leukemia protein sensitizes tumor necrosis factor alpha-induced apoptosis by inhibiting the NF-kappaB survival pathway

21 January 2018

1 reference

Promyelocytic leukemia zinc finger protein regulates interferon-mediated innate immunity

21 January 2018

1 reference

Autoantibodies to GW bodies and other autoantigens in primary biliary cirrhosis

21 January 2018

1 reference

TRIM8 modulates STAT3 activity through negative regulation of PIAS3.

21 January 2018

1 reference

Chronic inflammation in FMF: markers, risk factors, outcomes and therapy

21 January 2018

1 reference

Inflammasomes and autoimmunity

21 January 2018

1 reference

Interaction between pyrin and the apoptotic speck protein (ASC) modulates ASC-induced apoptosis

21 January 2018

1 reference

Pyrin activates the ASC pyroptosome in response to engagement by autoinflammatory PSTPIP1 mutants

21 January 2018

1 reference

The SPRY domain of Pyrin, mutated in familial Mediterranean fever patients, interacts with inflammasome components and inhibits proIL-1beta processing

21 January 2018

1 reference

Cryopyrin and pyrin activate caspase-1, but not NF-kappaB, via ASC oligomerization.

21 January 2018

1 reference

The familial Mediterranean fever protein, pyrin, is cleaved by caspase-1 and activates NF-kappaB through its N-terminal fragment

21 January 2018

1 reference

The B30.2 domain of pyrin, the familial Mediterranean fever protein, interacts directly with caspase-1 to modulate IL-1beta production

21 January 2018

1 reference

Evaluation of common mutations in the Mediterranean fever gene in Multiple Sclerosis patients: is it a susceptibility gene?

21 January 2018

1 reference

Pyrin binds the PSTPIP1/CD2BP1 protein, defining familial Mediterranean fever and PAPA syndrome as disorders in the same pathway

21 January 2018

1 reference

The estrogen-responsive B box protein: a novel enhancer of interleukin-1beta secretion

21 January 2018

1 reference

Tripartite-motif protein 30 negatively regulates NLRP3 inflammasome activation by modulating reactive oxygen species production

21 January 2018

1 reference

A role for mitochondria in NLRP3 inflammasome activation

21 January 2018

1 reference

TRIM30 alpha negatively regulates TLR-mediated NF-kappa B activation by targeting TAB2 and TAB3 for degradation

21 January 2018

1 reference

Human Trim5α has additional activities that are uncoupled from retroviral capsid recognition

21 January 2018

1 reference

TRIM5 is an innate immune sensor for the retrovirus capsid lattice

21 January 2018

1 reference

The tripartite motif family identifies cell compartments

21 January 2018

1 reference

A retrovirus restriction factor TRIM5alpha is transcriptionally regulated by interferons

21 January 2018

1 reference

Interferon-alpha induces up-regulation and nuclear translocation of the Ro52 autoantigen as detected by a panel of novel Ro52-specific monoclonal antibodies

21 January 2018

1 reference

Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes

21 January 2018

1 reference

Subcellular redistribution and surface exposure of the Ro52, Ro60 and La48 autoantigens during apoptosis in human ductal epithelial cells: a possible mechanism in the pathogenesis of Sjögren's syndrome

21 January 2018

1 reference

Targeted disruption of pyrin, the FMF protein, causes heightened sensitivity to endotoxin and a defect in macrophage apoptosis

21 January 2018

1 reference

Gfi-1B controls human erythroid and megakaryocytic differentiation by regulating TGF-beta signaling at the bipotent erythro-megakaryocytic progenitor stage

21 January 2018

1 reference

SS-56, a novel cellular target of autoantibody responses in Sjögren syndrome and systemic lupus erythematosus

21 January 2018

1 reference

Lessons from the inflammasome: a molecular sentry linking Candida and Crohn's disease

21 January 2018

1 reference

High Ro52 Expression in Spontaneous and UV-Induced Cutaneous Inflammation

31 March 2020

1 reference

Response to Comment on "Gene Disruption Study Reveals a Nonredundant Role for TRIM21/Ro52 in NF- B-Dependent Cytokine Expression in Fibroblasts"

31 March 2020

1 reference

The Ret finger protein inhibits signaling mediated by the noncanonical and canonical IkappaB kinase family members

31 March 2020

1 reference

KAP1 regulates type I interferon/STAT1-mediated IRF-1 gene expression

31 March 2020

1 reference

Serum interferon gamma in primary biliary cirrhosis: effect of ursodeoxycholic acid and prednisone therapy alone and in combination

31 March 2020

1 reference

TRIM8 regulates Nanog via Hsp90β-mediated nuclear translocation of STAT3 in embryonic stem cells

31 March 2020

1 reference

Anti-MDA5 and anti-TIF1-gamma antibodies have clinical significance for patients with dermatomyositis

31 March 2020

1 reference

Proinflammatory and antiinflammatory cytokines in multiple sclerosis and central nervous system acquired immunodeficiency syndrome

31 March 2020

1 reference

12 December 2020

Familial Mediterranean fever (FMF) and multiple sclerosis: an association study in one of the world's largest FMF cohorts

1 reference

12 December 2020

Induction of the PML protein by interferons in normal and APL cells.

1 reference

12 December 2020

Genetic variants and disease-associated factors contribute to enhanced interferon regulatory factor 5 expression in blood cells of patients with systemic lupus erythematosus

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRI3043

1 reference

14 March 2018

PubMed ID

21866173

1 reference

14 March 2018