Prediction of HLA class I-restricted T-cell epitopes of islet autoantigen combined with binding and dissociation assays. (Q51442203)

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20 January 2020

title

Prediction of HLA class I-restricted T-cell epitopes of islet autoantigen combined with binding and dissociation assays (English)

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20 January 2020

9

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20 January 2020

author name string

Xiangmei Wu

1

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20 January 2020

Xinyu Xu

2

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20 January 2020

Rong Gu

3

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20 January 2020

Zhixiao Wang

4

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20 January 2020

Heng Chen

5

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20 January 2020

Kuanfeng Xu

6

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20 January 2020

Mei Zhang

7

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20 January 2020

John Hutton

8

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20 January 2020

publication date

20 January 2012

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20 January 2020

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20 January 2020

volume

45

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20 January 2020

issue

2

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20 January 2020

page(s)

176-185

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A comprehensive guide to antibody and T-cell responses in type 1 diabetes.

20 January 2020

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CD8+ T cells in type 1 diabetes

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Autoreactive CD8 T cells in organ-specific autoimmunity: emerging targets for therapeutic intervention.

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CD8+ T cells in autoimmunity

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Human CD8 responses to a complete epitope set from preproinsulin: implications for approaches to epitope discovery.

21 January 2018

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Preproinsulin-specific CD8+ T cells secrete IFNgamma in human type 1 diabetes

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Recognition of a subregion of human proinsulin by class I-restricted T cells in type 1 diabetic patients

21 January 2018

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Identification of naturally processed HLA-A2--restricted proinsulin epitopes by reverse immunology.

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Cytotoxic T cells specific for glutamic acid decarboxylase in autoimmune diabetes

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Identification of Novel HLA-A*0201-restricted epitopes in recent-onset type 1 diabetic subjects and antibody-positive relatives

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Recognition of HLA class I-restricted beta-cell epitopes in type 1 diabetes.

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Zinc, a regulator of islet function and glucose homeostasis

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The cation efflux transporter ZnT8 (Slc30A8) is a major autoantigen in human type 1 diabetes

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New antigenic targets in type 1 diabetes

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Association between insulin secretion, insulin sensitivity and type 2 diabetes susceptibility variants identified in genome-wide association studies

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Down-regulation of ZnT8 expression in INS-1 rat pancreatic beta cells reduces insulin content and glucose-inducible insulin secretion

21 January 2018

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Genome-wide association studies provide new insights into type 2 diabetes aetiology

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SYFPEITHI: database for MHC ligands and peptide motifs

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CD8 T cell clones from young nonobese diabetic (NOD) islets can transfer rapid onset of diabetes in NOD mice in the absence of CD4 cells.

21 January 2018

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Determinant selection of major histocompatibility complex class I-restricted antigenic peptides is explained by class I-peptide affinity and is strongly influenced by nondominant anchor residues

21 January 2018

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Identification of new epitopes from four different tumor-associated antigens: recognition of naturally processed epitopes correlates with HLA-A*0201-binding affinity

21 January 2018

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A shared epitope of the interphotoreceptor retinoid-binding protein recognized by the CD4+ and CD8+ autoreactive T cells

21 January 2018

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Cytotoxic T cells to an epitope in the islet autoantigen IA-2 are not disease-specific

21 January 2018

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In vivo CTL induction with point-substituted ovalbumin peptides: immunogenicity correlates with peptide-induced MHC class I stability

21 January 2018

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Alternative splicing of G6PC2, the gene coding for the islet-specific glucose-6-phosphatase catalytic subunit-related protein (IGRP), results in differential expression in human thymus and spleen compared with pancreas

21 January 2018

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Immunology: Insulin auto-antigenicity in type 1 diabetes

21 January 2018

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A disease-associated cellular immune response in type 1 diabetics to an immunodominant epitope of insulin

21 January 2018

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Pro- and anti-inflammatory cytokine production by autoimmune T cells against preproinsulin in HLA-DRB1*04, DQ8 Type 1 diabetes

21 January 2018

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A genome-wide association study identifies novel risk loci for type 2 diabetes

21 January 2018

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Efficient MHC class I-peptide binding is required but does not ensure MHC class I-restricted immunogenicity

21 January 2018

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CD4+ and CD8+ T-cell clones from congenital rubella syndrome patients with IDDM recognize overlapping GAD65 protein epitopes

21 January 2018

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Identification of a -Cell-Specific HLA Class I Restricted Epitope in Type 1 Diabetes

21 January 2018

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21 January 2018

Identifiers

DOI

1 reference

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20 January 2020

1 reference