Genomewide comprehensive analysis reveals critical cooperation between Smad and c-Fos in RANKL-induced osteoclastogenesis. (Q51504232)

6 April 2018

title

Genomewide comprehensive analysis reveals critical cooperation between Smad and c-Fos in RANKL-induced osteoclastogenesis. (English)

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Koichi Matsuo

object named as

Koichi Matsuo

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Hiroyuki Aburatani

19

object named as

Hiroyuki Aburatani

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author name string

Yasunori Omata

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Tetsuro Yasui

2

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Jun Hirose

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Naohiro Izawa

4

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Yuuki Imai

5

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Takumi Matsumoto

6

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Hironari Masuda

7

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Naoto Tokuyama

8

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Shinya Nakamura

9

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Shuichi Tsutsumi

10

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Hisataka Yasuda

11

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Kazuo Okamoto

12

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Hiroshi Takayanagi

13

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Atsuhiko Hikita

14

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Takeshi Imamura

15

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Taku Saito

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Yuho Kadono

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publication date

1 May 2015

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Journal of Bone and Mineral Research

published in

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volume

30

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page(s)

869-877

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issue

5

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Signaling axis in osteoclast biology and therapeutic targeting in the RANKL/RANK/OPG system

cites work

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Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL

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Regulation of RANKL-induced osteoclastogenesis by TGF-β through molecular interaction between Smad3 and Traf6.

21 January 2018

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21 January 2018

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Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclasts

21 January 2018

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Smad3 and Smad4 cooperate with c-Jun/c-Fos to mediate TGF-beta-induced transcription

21 January 2018

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Direct binding of AP-1 (Fos/Jun) proteins to a SMAD binding element facilitates both gonadotropin-releasing hormone (GnRH)- and activin-mediated transcriptional activation of the mouse GnRH receptor gene

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Specific interactions between Smad proteins and AP-1 components determine TGFβ-induced breast cancer cell invasion.

21 January 2018

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21 January 2018

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Open chromatin defined by DNaseI and FAIRE identifies regulatory elements that shape cell-type identity

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Fosl1 is a transcriptional target of c-Fos during osteoclast differentiation

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Bone and haematopoietic defects in mice lacking c-fos

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Identifiers

DOI

10.1002/JBMR.2418

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6 April 2018

PubMed ID

25431176

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6 April 2018