Notch-dependent cell cycle arrest and apoptosis in mouse embryonic fibroblasts lacking Fbxw7. (Q51952187)

18 April 2018

title

Notch-dependent cell cycle arrest and apoptosis in mouse embryonic fibroblasts lacking Fbxw7. (English)

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18 April 2018

author name string

Y Ishikawa

1

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18 April 2018

I Onoyama

2

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18 April 2018

K I Nakayama

3

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18 April 2018

K Nakayama

4

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18 April 2018

language of work or name

English

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publication date

21 July 2008

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18 April 2018

published in

Oncogene

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18 April 2018

volume

27

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18 April 2018

issue

47

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18 April 2018

page(s)

6164-6174

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18 April 2018

https://scigraph.springernature.com/pub.10.1038/onc.2008.216

exact match

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cites work

FBXW7/hCDC4 is a general tumor suppressor in human cancer.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.216

Notch signaling: cell fate control and signal integration in development

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.216

Myc and Max function as a nucleoprotein complex

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.216

Glycogen synthase kinase-3beta modulates notch signaling and stability

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.216

Mastermind recruits CycC:CDK8 to phosphorylate the Notch ICD and coordinate activation with turnover

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.216

Fbxw7 contributes to tumor suppression by targeting multiple proteins for ubiquitin-dependent degradation.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.216

Notch controls proliferation and differentiation of stem cells in a dose-dependent manner.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.216

Functional interaction between SEL-10, an F-box protein, and the nuclear form of activated Notch1 receptor

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.216

Inducible gene knockout of transcription factor recombination signal binding protein-J reveals its essential role in T versus B lineage decision

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.216

Identification of p53 regulators by genome-wide functional analysis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.216

sel-10, a negative regulator of lin-12 activity in Caenorhabditis elegans, encodes a member of the CDC4 family of proteins

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.216

Functional conservation of mouse Notch receptor family members

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.216

An F-box protein, FWD1, mediates ubiquitin-dependent proteolysis of beta-catenin

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.216

Phosphorylation-dependent ubiquitination of cyclin E by the SCFFbw7 ubiquitin ligase

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.216

Formation and activation of a cyclin E-cdk2 complex during the G1 phase of the human cell cycle

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.216

A mouse model for cyclin E-dependent genetic instability and tumorigenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.216

Defective expression of Notch1 and Notch2 in connection to alterations of c-Myc and Ikaros in gamma-radiation-induced mouse thymic lymphomas.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.216

Fbxw7/Cdc4 is a p53-dependent, haploinsufficient tumour suppressor gene

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.216

Integrin-linked kinase controls Notch1 signaling by down-regulation of protein stability through Fbw7 ubiquitin ligase

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.216

Archipelago regulates Cyclin E levels in Drosophila and is mutated in human cancer cell lines

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.216

Plat-E: an efficient and stable system for transient packaging of retroviruses

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.216

Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.216

Ubiquitin ligases: cell-cycle control and cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.216

The ubiquitin ligase SCFFbw7 antagonizes apoptotic JNK signaling

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.216

Notch1 functions as a tumor suppressor in mouse skin

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.216

The Notch intracellular domain is ubiquitinated and negatively regulated by the mammalian Sel-10 homolog

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.216

FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to gamma-secretase inhibitors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.216

Conditional inactivation of Fbxw7 impairs cell-cycle exit during T cell differentiation and results in lymphomatogenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.216

The role of Notch in tumorigenesis: oncogene or tumour suppressor?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.216

Novel Notch alleles reveal a Deltex-dependent pathway repressing neural fate.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.216

Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.216

Drosophila shaggy kinase and rat glycogen synthase kinase-3 have conserved activities and act downstream of Notch.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.216

Notch1 modulates timing of G1-S progression by inducing SKP2 transcription and p27 Kip1 degradation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.216

Human F-box protein hCdc4 targets cyclin E for proteolysis and is mutated in a breast cancer cell line

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.216

Control of lipid metabolism by phosphorylation-dependent degradation of the SREBP family of transcription factors by SCF(Fbw7).

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.216

Defective cardiovascular development and elevated cyclin E and Notch proteins in mice lacking the Fbw7 F-box protein

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.216

The SCFFBW7 ubiquitin ligase complex as a tumor suppressor in T cell leukemia

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.216

Mouse Fbw7/Sel-10/Cdc4 is required for notch degradation during vascular development.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.216

The v-Jun point mutation allows c-Jun to escape GSK3-dependent recognition and destruction by the Fbw7 ubiquitin ligase

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.216

FBW7 ubiquitin ligase: a tumour suppressor at the crossroads of cell division, growth and differentiation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.216

The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.216

c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.216

Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.216

Notch activation induces apoptosis in neural progenitor cells through a p53-dependent pathway

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.216

Notch signaling is a potent inducer of growth arrest and apoptosis in a wide range of B-cell malignancies

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.216

31 March 2020

Identifiers

DOI

10.1038/ONC.2008.216

1 reference

18 April 2018

PubMed ID

18641686

1 reference

18 April 2018