p97/VCP- and Lys48-linked polyubiquitination form a new signaling pathway in DNA damage response. (Q53181384)

12 May 2018

title

p97/VCP- and Lys48-linked polyubiquitination form a new signaling pathway in DNA damage response. (English)

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12 May 2018

author name string

Kristijan Ramadan

series ordinal

1

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12 May 2018

publication date

15 March 2012

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12 May 2018

number of pages

8

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based on heuristic

inferred from page(s)

published in

Cell Cycle

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12 May 2018

volume

11

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12 May 2018

issue

6

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12 May 2018

page(s)

1062-1069

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12 May 2018

The DNA Damage Response: Making It Safe to Play with Knives

cites work

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19446

The DNA-damage response in human biology and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19446

More than just a focus: The chromatin response to DNA damage and its role in genome integrity maintenance

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19446

Chromatin dynamics and the repair of DNA double strand breaks

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19446

The ubiquitous role of ubiquitin in the DNA damage response

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19446

Crosstalk between histone modifications during the DNA damage response.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19446

Solving the RIDDLE of 53BP1 recruitment to sites of damage

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19446

The ubiquitin-selective segregase VCP/p97 orchestrates the response to DNA double-strand breaks.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19446

Role(s) of Cdc48/p97 in mitosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19446

UBXD7 binds multiple ubiquitin ligases and implicates p97 in HIF1alpha turnover

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19446

A ubiquitin-selective AAA-ATPase mediates transcriptional switching by remodelling a repressor-promoter DNA complex

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19446

The ubiquitin-selective chaperone CDC-48/p97, a new player in DNA replication

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19446

ERAD: the long road to destruction

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19446

Diverse functions with a common regulator: ubiquitin takes command of an AAA ATPase

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19446

Role of the ubiquitin-selective CDC48(UFD1/NPL4 )chaperone (segregase) in ERAD of OLE1 and other substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19446

Regulated endoplasmic reticulum-associated degradation of a polytopic protein: p97 recruits proteasomes to Insig-1 before extraction from membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19446

The AAA ATPase p97/VCP interacts with its alternative co-factors, Ufd1-Npl4 and p47, through a common bipartite binding mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19446

VCIP135 deubiquitinase and its binding protein, WAC, in p97ATPase-mediated membrane fusion

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19446

DNA damage modulates nucleolar interaction of the Werner protein with the AAA ATPase p97/VCP

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19446

Werner syndrome protein directly binds to the AAA ATPase p97/VCP in an ATP-dependent fashion

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19446

VCP, a weak ATPase involved in multiple cellular events, interacts physically with BRCA1 in the nucleus of living cells

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19446

GTPase-mediated regulation of the unfolded protein response in Caenorhabditis elegans is dependent on the AAA+ ATPase CDC-48.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19446

Degradation-linked ubiquitin signal and proteasome are integral components of DNA double strand break repair: New perspectives for anti-cancer therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19446

p97/VCP at the intersection of the autophagy and the ubiquitin proteasome system

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19446

Cdc48/p97-Ufd1-Npl4 antagonizes Aurora B during chromosome segregation in HeLa cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19446

RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19446

RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19446

Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19446

RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19446

The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19446

RAP80 targets BRCA1 to specific ubiquitin structures at DNA damage sites

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19446

Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19446

Ubiquitin-binding protein RAP80 mediates BRCA1-dependent DNA damage response

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19446

BRCA1-mediated ubiquitylation

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19446

Structural basis for specific recognition of Lys 63-linked polyubiquitin chains by tandem UIMs of RAP80

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19446

The AAA-ATPase VCP/p97 promotes 53BP1 recruitment by removing L3MBTL1 from DNA double-strand breaks

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19446

53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19446

53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19446

Loss of 53BP1 is a gain for BRCA1 mutant cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19446

Ku80 removal from DNA through double strand break-induced ubiquitylation

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19446

Visualizing the behavior of human Rad51 at the single-molecule level

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19446

RIDDLE immunodeficiency syndrome is linked to defects in 53BP1-mediated DNA damage signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19446

Critical roles of ring finger protein RNF8 in replication stress responses

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19446

The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER into the cytosol

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19446

Function of the p97-Ufd1-Npl4 complex in retrotranslocation from the ER to the cytosol: dual recognition of nonubiquitinated polypeptide segments and polyubiquitin chains

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19446

AAA-ATPase p97/Cdc48p, a cytosolic chaperone required for endoplasmic reticulum-associated protein degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19446

The AAA-ATPase Cdc48/p97 regulates spindle disassembly at the end of mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19446

Destroying the ring: Freeing DNA from Ku with ubiquitin

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19446

Saccharomyces Ku70, mre11/rad50 and RPA proteins regulate adaptation to G2/M arrest after DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19446

Ku prevents Exo1 and Sgs1-dependent resection of DNA ends in the absence of a functional MRX complex or Sae2

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19446

Release of Ku and MRN from DNA ends by Mre11 nuclease activity and Ctp1 is required for homologous recombination repair of double-strand breaks.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19446

Cdc48/p97 mediates UV-dependent turnover of RNA Pol II.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19446

CDC-48/p97 coordinates CDT-1 degradation with GINS chromatin dissociation to ensure faithful DNA replication

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19446

A genome-wide screen identifies p97 as an essential regulator of DNA damage-dependent CDT1 destruction.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19446

CUL4-DDB1 ubiquitin ligase interacts with multiple WD40-repeat proteins and regulates histone methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19446

Docking of a specialized PIP Box onto chromatin-bound PCNA creates a degron for the ubiquitin ligase CRL4Cdt2

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19446

ELA1 and CUL3 are required along with ELC1 for RNA polymerase II polyubiquitylation and degradation in DNA-damaged yeast cells

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19446

HERC2 is an E3 ligase that targets BRCA1 for degradation.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19446

Cdc48/p97 promotes reformation of the nucleus by extracting the kinase Aurora B from chromatin

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.11.6.19446

21 January 2018

Identifiers

DOI

10.4161/CC.11.6.19446

1 reference

12 May 2018

release_etyddpv2nnad5lpiuvuhtcm3rm

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/etyddpv2nnad5lpiuvuhtcm3rm

mapped directly with Wikidata item

24 November 2022

based on heuristic

PubMed ID

22391235

1 reference

12 May 2018