[Oxysterols: metabolism, biological role and associated diseases]. (Q53261375)

12 May 2018

review article

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title

[Oxysterols: metabolism, biological role and associated diseases]. (English)

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12 May 2018

author name string

Maâmar Souidi

1

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12 May 2018

Sandrine Dubrac

2

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12 May 2018

Michel Parquet

3

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12 May 2018

David H Volle

4

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12 May 2018

Jean-Marc A Lobaccaro

5

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12 May 2018

Denis Mathé

6

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12 May 2018

Olivier Combes

7

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12 May 2018

Pascale Scanff

8

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12 May 2018

Claude Lutton

9

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12 May 2018

Jocelyne Aigueperse

10

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12 May 2018

language of work or name

French

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publication date

1 March 2004

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12 May 2018

Gastroenterologie Clinique et Biologique

published in

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12 May 2018

volume

28

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12 May 2018

issue

3

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12 May 2018

page(s)

279-293

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12 May 2018

Oxysterols: friends, foes, or just fellow passengers?

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cDNA cloning of mouse and human cholesterol 25-hydroxylases, polytopic membrane proteins that synthesize a potent oxysterol regulator of lipid metabolism

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7-ketocholesterol, a specific indicator of lipoprotein oxidation, and malondialdehyde in non-insulin dependent diabetes and peripheral vascular disease

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Oxysterols and atherosclerosis

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The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor

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Regulation of gene expression by SREBP and SCAP.

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The hypocholesterolemic agent LY295427 up-regulates INSIG-1, identifying the INSIG-1 protein as a mediator of cholesterol homeostasis through SREBP

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SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver

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Bisphosphonate mechanism of action

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7 January 2021

Novel putative SREBP and LXR target genes identified by microarray analysis in liver of cholesterol-fed mice

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7 January 2021

The LXRs: a new class of oxysterol receptors

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7 January 2021

Nuclear receptors and lipid physiology: opening the X-files

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7 January 2021

Activation of mammalian retinoid X receptors by the insect growth regulator methoprene

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The RXR heterodimers and orphan receptors

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LXR, a nuclear receptor that defines a distinct retinoid response pathway

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Structural requirements of ligands for the oxysterol liver X receptors LXRalpha and LXRbeta

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Auto-oxidized cholesterol sulfates are antagonistic ligands of liver X receptors: implications for the development and treatment of atherosclerosis

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Unsaturated fatty acids inhibit transcription of the sterol regulatory element-binding protein-1c (SREBP-1c) gene by antagonizing ligand-dependent activation of the LXR.

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7 January 2021

Synthetic LXR ligand inhibits the development of atherosclerosis in mice

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7 January 2021

Induction of intestinal ATP-binding cassette transporters by a phytosterol-derived liver X receptor agonist

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7 January 2021

The liver X receptor gene team: potential new players in atherosclerosis

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7 January 2021

Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR alpha

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7 January 2021

Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors

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7 January 2021

Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbeta

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Regulation of absorption and ABC1-mediated efflux of cholesterol by RXR heterodimers

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Human white/murine ABC8 mRNA levels are highly induced in lipid-loaded macrophages. A transcriptional role for specific oxysterols

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Regulation of ATP-binding cassette sterol transporters ABCG5 and ABCG8 by the liver X receptors alpha and beta.

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7 January 2021

The human ABCG4 gene is regulated by oxysterols and retinoids in monocyte-derived macrophages

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7 January 2021

Efflux and atherosclerosis: the clinical and biochemical impact of variations in the ABCA1 gene

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Sterol upregulation of human CETP expression in vitro and in transgenic mice by an LXR element

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7 January 2021

Phospholipid transfer protein is regulated by liver X receptors in vivo

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LXRs control lipid-inducible expression of the apolipoprotein E gene in macrophages and adipocytes

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Reduction of atherosclerosis in apolipoprotein E knockout mice by activation of the retinoid X receptor.

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Regulation of lipoprotein lipase by the oxysterol receptors, LXRalpha and LXRbeta.

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7 January 2021

Direct and indirect mechanisms for regulation of fatty acid synthase gene expression by liver X receptors

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7 January 2021

Stearoyl-CoA desaturase inhibits ATP-binding cassette transporter A1-mediated cholesterol efflux and modulates membrane domain structure

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7 January 2021

Antidiabetic action of a liver x receptor agonist mediated by inhibition of hepatic gluconeogenesis.

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7 January 2021

Expression of the insulin-responsive glucose transporter GLUT4 in adipocytes is dependent on liver X receptor alpha

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7 January 2021

Oxysterol stimulation of epidermal differentiation is mediated by liver X receptor-beta in murine epidermis.

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7 January 2021

Liver X receptors in the central nervous system: from lipid homeostasis to neuronal degeneration

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7 January 2021

Angiopoietin-like protein 3 mediates hypertriglyceridemia induced by the liver X receptor.

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7 January 2021

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7 January 2021

Effects of dietary 27-hydroxycholesterol on cholesterol metabolism and bile acid biosynthesis in the hamster

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The neurotoxic effect of 24-hydroxycholesterol on SH-SY5Y human neuroblastoma cells.

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7 January 2021

Neurotoxicity of 25-OH-cholesterol on sympathetic neurons

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7 January 2021

Neurotoxicity of 25-OH-cholesterol on NGF-differentiated PC12 cells

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7 January 2021

Neurotoxicity of cholesterol oxides on cultured cerebellar granule cells

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7 January 2021

Characterization and comparison of the mode of cell death, apoptosis versus necrosis, induced by 7beta-hydroxycholesterol and 7-ketocholesterol in the cells of the vascular wall

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7 January 2021

Oxysterols induce interleukin-1beta production in human macrophages

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7 January 2021

Identification of oxysterols in human bile and pigment gallstones

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7 January 2021

Good cholesterol, bad cholesterol: role of oxysterols in biliary tract diseases

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7 January 2021

Cholestan-3beta,5alpha,6beta-triol, but not 7-ketocholesterol, suppresses taurocholate-induced mucin secretion by cultured dog gallbladder epithelial cells

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7 January 2021

Oxidized cholesterol modulates age‐related change in lipid metabolism in rats

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7 January 2021

Lymphatic absorption of oxidized cholesterol in rats

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7 January 2021

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7 January 2021

Insulin injections enhance cholesterol gallstone incidence by changing the biliary cholesterol saturation index and apo A-I concentration in hamsters fed a lithogenic diet

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7 January 2021

Angiotoxicity of oxygenated sterols and possible precursors

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7 January 2021

Oxidized cholesterol in the diet accelerates the development of aortic atherosclerosis in cholesterol-fed rabbits

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7 January 2021

Comparative atherogenic effects of cholesterol and cholesterol oxides

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7 January 2021

Cholesterol hydroperoxides inhibit calmodulin and suppress atherogenesis in rabbits

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7 January 2021

Effects of dietary oxysterols on coronary arteries in hyperlipidaemic hamsters

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7 January 2021

Dietary cholesterol-oxidation products accumulate in serum and liver in apolipoprotein E-deficient mice, but do not accelerate atherosclerosis

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7 January 2021

Different patterns of IL-1beta secretion, adhesion molecule expression and apoptosis induction in human endothelial cells treated with 7alpha-, 7beta-hydroxycholesterol, or 7-ketocholesterol

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7 January 2021

Oxysterol activators of liver X receptor and 9-cis-retinoic acid promote sequential steps in the synthesis and secretion of tumor necrosis factor-alpha from human monocytes

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7 January 2021

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7 January 2021

Up-regulation of the fibrogenic cytokine TGF-beta1 by oxysterols: a mechanistic link between cholesterol and atherosclerosis.

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7 January 2021

Inhibition by cholesterol oxides of NO release from human vascular endothelial cells

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7 January 2021

Cerebrospinal fluid 24S-hydroxycholesterol is increased in patients with Alzheimer's disease compared to healthy controls

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7 January 2021

Polymorphism in the cholesterol 24S-hydroxylase gene is associated with Alzheimer's disease

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7 January 2021

Plasma 24S-hydroxycholesterol: a peripheral indicator of neuronal degeneration and potential state marker for Alzheimer's disease.

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7 January 2021

Induction of the cholesterol transporter ABCA1 in central nervous system cells by liver X receptor agonists increases secreted Abeta levels

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7 January 2021

Defective cholesterol biosynthesis associated with the Smith-Lemli-Opitz syndrome

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7 January 2021

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Identifiers

DOI

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12 May 2018

1 reference

12 May 2018