Viral manipulation of STAT3: Evade, exploit, and injure. (Q54255379)

http://europepmc.org/abstract/PMC/5854428

26 May 2018

1 reference

22 December 2019

Viral manipulation of STAT3: Evade, exploit, and injure. (English)

1 reference

http://europepmc.org/abstract/PMC/5854428

26 May 2018

main subject

viral infectious disease

1 reference

22 December 2019

1 reference

3 November 2019

signal transducer and activator of transcription 3

1 reference

22 December 2019

1 reference

PubMed publication ID

29543893

author

Armando Andres Roca Suarez

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29543893%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Joachim Lupberger

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29543893%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

3

Thomas F Baumert

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29543893%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

2

Nicolaas Van Renne

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29543893%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

language of work or name

1 reference

15 March 2018

1 reference

http://europepmc.org/abstract/PMC/5854428

26 May 2018

1 March 2018

4 references

23 March 2019

3 November 2019

20 November 2019

22 December 2019

5 references

23 March 2019

3 November 2019

20 November 2019

22 December 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29543893%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

volume

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29543893%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29543893%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

page(s)

e1006839

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29543893%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

7 June 2020

copyright license

4 references

23 March 2019

3 November 2019

20 November 2019

on focus list of Wikimedia project

22 December 2019

copyright status

copyrighted

0 references

ScienceSource

0 references

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27 May 2018

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27 May 2018

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CD45 Phosphatase Inhibits STAT3 Transcription Factor Activity in Myeloid Cells and Promotes Tumor-Associated Macrophage Differentiation

27 May 2018

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HBV-induced ROS accumulation promotes hepatocarcinogenesis through Snail-mediated epigenetic silencing of SOCS3.

27 May 2018

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27 May 2018

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27 May 2018

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The phosphatase DUSP2 controls the activity of the transcription activator STAT3 and regulates TH17 differentiation

27 May 2018

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STAT3 Regulates Lytic Activation of Kaposi's Sarcoma-Associated Herpesvirus.

27 May 2018

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Special suppressive role of miR-29b in HER2-positive breast cancer cells by targeting Stat3.

27 May 2018

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STAT3 is involved in miR-124-mediated suppressive effects on esophageal cancer cells

27 May 2018

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27 May 2018

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27 May 2018

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27 May 2018

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27 May 2018

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27 May 2018

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27 May 2018

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27 May 2018

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STAT3 activation by KSHV correlates with IL-10, IL-6 and IL-23 release and an autophagic block in dendritic cells

27 May 2018

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MicroRNA let-7 downregulates STAT3 phosphorylation in pancreatic cancer cells by increasing SOCS3 expression.

27 May 2018

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27 May 2018

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STAT3 regulates proliferation and survival of CD8+ T cells: enhances effector responses to HSV-1 infection, and inhibits IL-10+ regulatory CD8+ T cells in autoimmune uveitis

27 May 2018

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Human metapneumovirus inhibits the IL-6-induced JAK/STAT3 signalling cascade in airway epithelium.

27 May 2018

1 reference

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STAT heterodimers in immunity: A mixed message or a unique signal?

27 May 2018

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Human cytomegalovirus IE1 protein disrupts interleukin-6 signaling by sequestering STAT3 in the nucleus.

27 May 2018

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27 May 2018

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27 May 2018

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27 May 2018

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The rabies virus interferon antagonist P protein interacts with activated STAT3 and inhibits Gp130 receptor signaling

27 May 2018

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27 May 2018

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27 May 2018

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27 May 2018

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The Sin3a repressor complex is a master regulator of STAT transcriptional activity

27 May 2018

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27 May 2018

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27 May 2018

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Functional STAT3 deficiency compromises the generation of human T follicular helper cells.

27 May 2018

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Signal transducer and activator of transcription 3 (STAT3) and survivin induction by varicella-zoster virus promote replication and skin pathogenesis

27 May 2018

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27 May 2018

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27 May 2018

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IL-21 and IL-6 are critical for different aspects of B cell immunity and redundantly induce optimal follicular helper CD4 T cell (Tfh) differentiation

27 May 2018

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Epstein-Barr virus LMP1 activates EGFR, STAT3, and ERK through effects on PKCdelta

27 May 2018

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Reversible methylation of promoter-bound STAT3 by histone-modifying enzymes

27 May 2018

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27 May 2018

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HCMV-encoded chemokine receptor US28 mediates proliferative signaling through the IL-6-STAT3 axis

27 May 2018

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Lethal-7 is down-regulated by the hepatitis B virus x protein and targets signal transducer and activator of transcription 3.

27 May 2018

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Curcumin inhibits hepatitis C virus replication via suppressing the Akt-SREBP-1 pathway

27 May 2018

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Common threads in persistent viral infections

27 May 2018

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BioGPS: an extensible and customizable portal for querying and organizing gene annotation resources

27 May 2018

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STAT3 activation contributes directly to Epstein-Barr virus-mediated invasiveness of nasopharyngeal cancer cells in vitro.

27 May 2018

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The tyrosine phosphatase PTPRD is a tumor suppressor that is frequently inactivated and mutated in glioblastoma and other human cancers

27 May 2018

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Initiation of Hepatitis C Virus Infection Requires the Dynamic Microtubule Network: ROLE OF THE VIRAL NUCLEOCAPSID PROTEIN

27 May 2018

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Function of mitochondrial Stat3 in cellular respiration

27 May 2018

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Therapeutic targeting of IL-6 trans signaling counteracts STAT3 control of experimental inflammatory arthritis

27 May 2018

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IL-6 controls Th17 immunity in vivo by inhibiting the conversion of conventional T cells into Foxp3+ regulatory T cells

27 May 2018

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A dynamic view of hepatitis C virus replication complexes

27 May 2018

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Paradigm shifts in the cell biology of STAT signaling

27 May 2018

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The hepatitis E virus ORF3 protein modulates epidermal growth factor receptor trafficking, STAT3 translocation, and the acute-phase response

27 May 2018

1 reference

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STAT3 mutations in the hyper-IgE syndrome

27 May 2018

1 reference

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SOCS proteins, cytokine signalling and immune regulation

27 May 2018

1 reference

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Unphosphorylated STAT3 accumulates in response to IL-6 and activates transcription by binding to NFkappaB

27 May 2018

1 reference

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Identification of STAT3 as a substrate of receptor protein tyrosine phosphatase T

27 May 2018

1 reference

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Crosstalk between cancer and immune cells: role of STAT3 in the tumour microenvironment.

27 May 2018

1 reference

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MUC1 induced by Epstein-Barr virus latent membrane protein 1 causes dissociation of the cell-matrix interaction and cellular invasiveness via STAT signaling

27 May 2018

1 reference

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The cytomegalovirus homolog of interleukin-10 requires phosphatidylinositol 3-kinase activity for inhibition of cytokine synthesis in monocytes

27 May 2018

1 reference

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The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5854428

Resveratrol inhibition of varicella-zoster virus replication in vitro

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5854428

Role of STAT3 in type I interferon responses. Negative regulation of STAT1-dependent inflammatory gene activation

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5854428

Stat3 regulates microtubules by antagonizing the depolymerization activity of stathmin

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5854428

IL-6 trans-signaling via STAT3 directs T cell infiltration in acute inflammation.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5854428

Stat3 dimerization regulated by reversible acetylation of a single lysine residue

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5854428

STAT protein interference and suppression of cytokine signal transduction by measles virus V protein

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5854428

STAT3 ubiquitylation and degradation by mumps virus suppress cytokine and oncogene signaling

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5854428

A positive autoregulatory loop of LMP1 expression and STAT activation in epithelial cells latently infected with Epstein-Barr virus.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5854428

Activation of STAT3 by the Hepatitis C Virus Core Protein Leads to Cellular Transformation

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5854428

STAT3 activation by type I interferons is dependent on specific tyrosines located in the cytoplasmic domain of interferon receptor chain 2c. Activation of multiple STATS proceeds through the redundant usage of two tyrosine residues

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5854428

Interaction between STAT-3 and HNF-3 leads to the activation of liver-specific hepatitis B virus enhancer 1 function

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5854428

Human hepatitis C virus NS5A protein alters intracellular calcium levels, induces oxidative stress, and activates STAT-3 and NF-kappa B.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5854428

IL-6 switches the differentiation of monocytes from dendritic cells to macrophages

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5854428

Suppressor of cytokine signaling-3 preferentially binds to the SHP-2-binding site on the shared cytokine receptor subunit gp130

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5854428

Human cytomegalovirus harbors its own unique IL-10 homolog (cmvIL-10)

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5854428

Human CD4+ T lymphocytes with remarkable regulatory functions on dendritic cells and nickel-specific Th1 immune responses

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5854428

A single amino acid determines the immunostimulatory activity of interleukin 10.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5854428

Human herpesvirus 8 interleukin-6 (vIL-6) signals through gp130 but has structural and receptor-binding properties distinct from those of human IL-6.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5854428

Cytokine-inducible SH2 protein-3 (CIS3/SOCS3) inhibits Janus tyrosine kinase by binding through the N-terminal kinase inhibitory region as well as SH2 domain

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5854428

HBx protein of hepatitis B virus activates Jak1-STAT signaling

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5854428

Specific inhibition of Stat3 signal transduction by PIAS3

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5854428

Role of IL-6 and its soluble receptor in induction of chemokines and leukocyte recruitment.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5854428

Dominant negative stat3 mutant inhibits interleukin-6-induced Jak-STAT signal transduction

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5854428

STAT3 participates in transcriptional activation of the C-reactive protein gene by interleukin-6.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5854428

Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5854428

Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5854428

JAK3: a novel JAK kinase associated with terminal differentiation of hematopoietic cells.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5854428

Molecular cloning of APRF, a novel IFN-stimulated gene factor 3 p91-related transcription factor involved in the gp130-mediated signaling pathway

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5854428

tyk2, prototype of a novel class of non-receptor tyrosine kinase genes

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5854428

Homology of cytokine synthesis inhibitory factor (IL-10) to the Epstein-Barr virus gene BCRFI.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5854428

Two novel protein-tyrosine kinases, each with a second phosphotransferase-related catalytic domain, define a new class of protein kinase

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5854428

Targeting Oncogenic Transcription Factors: Therapeutic Implications of Endogenous STAT Inhibitors

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5854428

MiR-519a functions as a tumor suppressor in glioma by targeting the oncogenic STAT3 pathway

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5854428

Kaposi's sarcoma-associated herpesvirus kaposin B induces unique monophosphorylation of STAT3 at serine 727 and MK2-mediated inactivation of the STAT3 transcriptional repressor TRIM28.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5854428

STAT3 negatively regulates type I IFN-mediated antiviral response.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5854428

The multi-targeted kinase inhibitor sorafenib inhibits human cytomegalovirus replication.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5854428

Epstein-Barr virus-derived EBNA2 regulates STAT3 activation

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5854428

Novel roles of unphosphorylated STAT3 in oncogenesis and transcriptional regulation

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5854428

IL-6 induces an anti-inflammatory response in the absence of SOCS3 in macrophages

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5854428

Interleukin-6 and the granulocyte colony-stimulating factor receptor are major independent regulators of granulopoiesis in vivo but are not required for lineage commitment or terminal differentiation.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5854428

13 August 2018

Hepatocellular carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5854428

The role of IL-10 in human B cell activation, proliferation, and differentiation

30 November 2018

1 reference

12 December 2020

IL-6 and Its Soluble Receptor Orchestrate a Temporal Switch in the Pattern of Leukocyte Recruitment Seen during Acute Inflammation

1 reference

12 December 2020

Human Cytomegalovirus Binding to DC-SIGN Is Required for Dendritic Cell Infection and Target Cell trans-Infection

1 reference

12 December 2020

ICAM-1 triggers liver regeneration through leukocyte recruitment and Kupffer cell-dependent release of TNF-alpha/IL-6 in mice

1 reference

12 December 2020

Shaping phenotype, function, and survival of dendritic cells by cytomegalovirus-encoded IL-10

1 reference

12 December 2020

IL-6 increases primed cell expansion and survival

1 reference

12 December 2020

1 reference

12 December 2020

10.1371/JOURNAL.PPAT.1006839

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29543893%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29543893%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

PubMed publication ID

29543893

1 reference