Atrogin-1/MAFbx and MuRF1 are downregulated in aging-related loss of skeletal muscle. (Q54590411)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16870627%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

title

Atrogin-1/MAFbx and MuRF1 are downregulated in aging-related loss of skeletal muscle (English)

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27 December 2019

2

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27 December 2019

Martin Hägglund

series ordinal

3

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27 December 2019

author name string

Erik Edström

series ordinal

1

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27 December 2019

Brun Ulfhake

series ordinal

4

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27 December 2019

language of work or name

English

0 references

publication date

1 July 2006

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The Journals of Gerontology

27 December 2019

published in

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27 December 2019

volume

61

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27 December 2019

page(s)

663-674

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27 December 2019

issue

7

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Skeletal muscle hypertrophy and atrophy signaling pathways

27 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F61.7.663

What do we really know about the ubiquitin-proteasome pathway in muscle atrophy?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F61.7.663

Altered responses in skeletal muscle protein turnover during aging in anabolic and catabolic periods.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F61.7.663

Mechanisms of muscle wasting. The role of the ubiquitin-proteasome pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F61.7.663

Multiple types of skeletal muscle atrophy involve a common program of changes in gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F61.7.663

Regulation of microtubule dynamics and myogenic differentiation by MURF, a striated muscle RING-finger protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F61.7.663

Atrogin-1, a muscle-specific F-box protein highly expressed during muscle atrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F61.7.663

Identification of ubiquitin ligases required for skeletal muscle atrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F61.7.663

Mediation of IGF-1-induced skeletal myotube hypertrophy by PI(3)K/Akt/mTOR and PI(3)K/Akt/GSK3 pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F61.7.663

Foxo transcription factors induce the atrophy-related ubiquitin ligase atrogin-1 and cause skeletal muscle atrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F61.7.663

IGF-I stimulates muscle growth by suppressing protein breakdown and expression of atrophy-related ubiquitin ligases, atrogin-1 and MuRF1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F61.7.663

The IGF-1/PI3K/Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F61.7.663

Human-specific subfamilies of HERV-K (HML-2) long terminal repeats: three master genes were active simultaneously during branching of hominoid lineages.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F61.7.663

Transcriptional profiling identifies extensive downregulation of extracellular matrix gene expression in sarcopenic rat soleus muscle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F61.7.663

Insulin-like growth factor-1 (IGF-1) inversely regulates atrophy-induced genes via the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin (PI3K/Akt/mTOR) pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F61.7.663

Transgenic overexpression of locally acting insulin-like growth factor-1 inhibits ubiquitin-mediated muscle atrophy in chronic left-ventricular dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F61.7.663

Insulin-induced phosphorylation of FKHR (Foxo1) targets to proteasomal degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F61.7.663

Akt activation promotes degradation of tuberin and FOXO3a via the proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F61.7.663

The ins and outs of FoxO shuttling: mechanisms of FoxO translocation and transcriptional regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F61.7.663

Molecular mechanisms modulating muscle mass

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F61.7.663

Signaling via Shc family adapter proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F61.7.663

New role for Shc in activation of the phosphatidylinositol 3-kinase/Akt pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F61.7.663

Differential regulation of Shc adaptor proteins in skeletal muscle, spinal cord and forebrain of aged rats with sensorimotor impairment

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F61.7.663

Regulation of IRS-1/SHP2 interaction and AKT phosphorylation in animal models of insulin resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F61.7.663

Caloric restriction modulates early events in insulin signaling in liver and skeletal muscle of rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F61.7.663

Effect of aging on insulin receptor, insulin receptor substrate-1, and phosphatidylinositol 3-kinase in liver and muscle of rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F61.7.663

Impairment of peripheral sensory innervation in senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F61.7.663

Sarcopenia is not due to lack of regenerative drive in senescent skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F61.7.663

Regulation of neurotrophin signaling in aging sensory and motoneurons: dissipation of target support?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F61.7.663

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F61.7.663

Absolute quantification of mRNA using real-time reverse transcription polymerase chain reaction assays

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F61.7.663

Triple layer control: phosphorylation, acetylation and ubiquitination of FOXO proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F61.7.663

Skeletal muscle gene expression profiles in 20-29 year old and 65-71 year old women.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F61.7.663

Effects of aging and caloric restriction on the gene expression of Foxo1, 3, and 4 (FKHR, FKHRL1, and AFX) in the rat skeletal muscles

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F61.7.663

Phosphorylation of serine 256 suppresses transactivation by FKHR (FOXO1) by multiple mechanisms. Direct and indirect effects on nuclear/cytoplasmic shuttling and DNA binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F61.7.663

Inhibition of nuclear import by protein kinase B (Akt) regulates the subcellular distribution and activity of the forkhead transcription factor AFX.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F61.7.663

Roles of the forkhead in rhabdomyosarcoma (FKHR) phosphorylation sites in regulating 14-3-3 binding, transactivation and nuclear targetting

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F61.7.663

Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F61.7.663

The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F61.7.663

Recent advances in the protein kinase B signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F61.7.663

Molecular determinants of skeletal muscle mass: getting the "AKT" together

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F61.7.663

Akt: versatile mediator of cell survival and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F61.7.663

Liver-derived insulin-like growth factor I (IGF-I) is the principal source of IGF-I in blood but is not required for postnatal body growth in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F61.7.663

Localized Igf-1 transgene expression sustains hypertrophy and regeneration in senescent skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F61.7.663

Viral mediated expression of insulin-like growth factor I blocks the aging-related loss of skeletal muscle function

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F61.7.663

Signaling pathways weigh in on decisions to make or break skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F61.7.663

Protein kinase B beta/Akt2 plays a specific role in muscle differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F61.7.663

Positive feedback regulation between Akt2 and MyoD during muscle differentiation. Cloning of Akt2 promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F61.7.663

Differentiation stage-specific inhibition of the Raf-MEK-ERK pathway by Akt.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F61.7.663

Phosphorylation and regulation of Raf by Akt (protein kinase B)

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F61.7.663

The p66shc adaptor protein controls oxidative stress response and life span in mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F61.7.663

Redox regulation of forkhead proteins through a p66shc-dependent signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F61.7.663

Minireview: the role of oxidative stress in relation to caloric restriction and longevity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F61.7.663

Role of the p66Shc isoform in insulin-like growth factor I receptor signaling through MEK/Erk and regulation of actin cytoskeleton in rat myoblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F61.7.663

Akt phosphorylation is not sufficient for insulin-like growth factor-stimulated myogenin expression but must be accompanied by down-regulation of mitogen-activated protein kinase/extracellular signal-regulated kinase phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F61.7.663

Sensitivity and protein turnover response to glucocorticoids are different in skeletal muscle from adult and old rats. Lack of regulation of the ubiquitin-proteasome proteolytic pathway in aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F61.7.663

Altered proteasome structure, function, and oxidation in aged muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F61.7.663

Altered proteasome function and subunit composition in aged muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F61.7.663