An automated high-resolution in vivo screen in zebrafish to identify chemical regulators of myelination (Q56810654)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29979149%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

title

An automated high-resolution in vivo screen in zebrafish to identify chemical regulators of myelination (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29979149%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

0 references

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29979149%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

Katy L H Cole

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29979149%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

David A Lyons

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29979149%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

author name string

Jill M Williamson

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29979149%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

Matthew Swire

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29979149%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

Hari Kamadurai

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29979149%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

Marc Muskavitch

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29979149%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

language of work or name

English

0 references

publication date

6 July 2018

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29979149%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29979149%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

volume

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29979149%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

5 April 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6056238/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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Regeneration of myelin sheaths of normal length and thickness in the zebrafish CNS correlates with growth of axons in caliber

2 November 2018

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Identification of the Kappa-Opioid Receptor as a Therapeutic Target for Oligodendrocyte Remyelination.

2 November 2018

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Epigenetic control of oligodendrocyte development: adding new players to old keepers

2 November 2018

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Hdac3 Interaction with p300 Histone Acetyltransferase Regulates the Oligodendrocyte and Astrocyte Lineage Fate Switch

2 November 2018

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Clobetasol and Halcinonide Act as Smoothened Agonists to Promote Myelin Gene Expression and RxRγ Receptor Activation

2 November 2018

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Olig1 Acetylation and Nuclear Export Mediate Oligodendrocyte Development

2 November 2018

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Fbxw7 Limits Myelination by Inhibiting mTOR Signaling.

2 November 2018

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Inhibition of Gli1 mobilizes endogenous neural stem cells for remyelination

2 November 2018

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Zebrafish as tools for drug discovery

2 November 2018

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Insights into mechanisms of central nervous system myelination using zebrafish

2 November 2018

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First quantitative high-throughput screen in zebrafish identifies novel pathways for increasing pancreatic β-cell mass.

2 November 2018

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The ImageJ ecosystem: An open platform for biomedical image analysis

2 November 2018

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Neuronal Activity Promotes Glioma Growth through Neuroligin-3 Secretion

2 November 2018

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Drug-based modulation of endogenous stem cells promotes functional remyelination in vivo

2 November 2018

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Mutant huntingtin downregulates myelin regulatory factor-mediated myelin gene expression and affects mature oligodendrocytes

2 November 2018

1 reference

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Differential expression of sirtuin family members in the developing, adult, and aged rat brain.

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6056238

15 years of zebrafish chemical screening

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6056238

Dynamics of oligodendrocyte generation and myelination in the human brain.

2 November 2018

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High-content phenotypic screening and triaging strategy to identify small molecules driving oligodendrocyte progenitor cell differentiation

2 November 2018

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Myelination of the nervous system: mechanisms and functions

2 November 2018

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An RNA-sequencing transcriptome and splicing database of glia, neurons, and vascular cells of the cerebral cortex.

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6056238

Micropillar arrays as a high-throughput screening platform for therapeutics in multiple sclerosis.

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6056238

Evidence for morphological alterations in prefrontal white matter glia in schizophrenia and bipolar disorder

2 November 2018

1 reference

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Myelin membrane wrapping of CNS axons by PI(3,4,5)P3-dependent polarized growth at the inner tongue

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6056238

A regenerative approach to the treatment of multiple sclerosis

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6056238

Pharmacological inactivation of Skp2 SCF ubiquitin ligase restricts cancer stem cell traits and cancer progression

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6056238

Individual oligodendrocytes have only a few hours in which to generate new myelin sheaths in vivo

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6056238

Delayed myelination in a mouse model of fragile X syndrome.

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6056238

Expansion of oligodendrocyte progenitor cells following SIRT1 inactivation in the adult brain.

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6056238

Insufficient OPC migration into demyelinated lesions is a cause of poor remyelination in MS and mouse models

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6056238

Degeneration and impaired regeneration of gray matter oligodendrocytes in amyotrophic lateral sclerosis.

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6056238

Target identification and mechanism of action in chemical biology and drug discovery

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6056238

Oligodendrocyte dynamics in the healthy adult CNS: evidence for myelin remodeling

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6056238

Protecting white matter from stroke injury.

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6056238

Myelin breakdown mediates age-related slowing in cognitive processing speed in healthy elderly men.

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6056238

Characterisation of a Tip60 specific inhibitor, NU9056, in prostate cancer

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6056238

A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6056238

Fiji: an open-source platform for biological-image analysis

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6056238

Arrested preoligodendrocyte maturation contributes to myelination failure in premature infants

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6056238

Fully automated cellular-resolution vertebrate screening platform with parallel animal processing.

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6056238

Dissecting mechanisms of myelinated axon formation using zebrafish

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6056238

Individual axons regulate the myelinating potential of single oligodendrocytes in vivo

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6056238

Sirt2 is a novel in vivo downstream target of Nkx2.2 and enhances oligodendroglial cell differentiation

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6056238

Changed histone acetylation patterns in normal-appearing white matter and early multiple sclerosis lesions

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6056238

High-throughput in vivo vertebrate screening

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6056238

CNS-resident glial progenitor/stem cells produce Schwann cells as well as oligodendrocytes during repair of CNS demyelination.

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6056238

Chemical inducers and transcriptional markers of oligodendrocyte differentiation

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6056238

Virtual ligand screening of the p300/CBP histone acetyltransferase: identification of a selective small molecule inhibitor

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6056238

A general factor of brain white matter integrity predicts information processing speed in healthy older people.

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6056238

Drug reprofiling using zebrafish identifies novel compounds with potential pro-myelination effects

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6056238

Zebrafish behavioral profiling links drugs to biological targets and rest/wake regulation

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6056238

Characterization of sirtuin inhibitors in nematodes expressing a muscular dystrophy protein reveals muscle cell and behavioral protection by specific sirtinol analogues

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6056238

Alzheimer's disease as homeostatic responses to age-related myelin breakdown

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6056238

Kif1b is essential for mRNA localization in oligodendrocytes and development of myelinated axons

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6056238

Epigenetic mechanisms facilitating oligodendrocyte development, maturation, and aging

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6056238

Globally optimal stitching of tiled 3D microscopic image acquisitions

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6056238

Zebrafish myelination: a transparent model for remyelination?

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6056238

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6056238

Reconstruction of zebrafish early embryonic development by scanned light sheet microscopy

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6056238

Genes involved in leukodystrophies: a glance at glial functions.

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6056238

Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6056238

Proteolipid protein is required for transport of sirtuin 2 into CNS myelin

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6056238

Prostaglandin E2 regulates vertebrate haematopoietic stem cell homeostasis

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6056238

Sirtuin 2, a mammalian homolog of yeast silent information regulator-2 longevity regulator, is an oligodendroglial protein that decelerates cell differentiation through deacetylating alpha-tubulin

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6056238

In vivo time-lapse imaging shows dynamic oligodendrocyte progenitor behavior during zebrafish development.

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6056238

White matter integrity and cognition in childhood and old age.

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6056238

Histone deacetylase 1 is essential for oligodendrocyte specification in the zebrafish CNS.

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6056238

Chemical suppression of a genetic mutation in a zebrafish model of aortic coarctation

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6056238

Neural cell fate analysis in zebrafish using olig2 BAC transgenics.

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6056238

NG2-expressing glial progenitor cells: an abundant and widespread population of cycling cells in the adult rat CNS.

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6056238

Drugs that induce repolarization abnormalities cause bradycardia in zebrafish

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6056238

Identification of a small molecule inhibitor of Sir2p

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6056238

Small molecule developmental screens reveal the logic and timing of vertebrate development

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6056238

NG2-positive oligodendrocyte progenitor cells in adult human brain and multiple sclerosis lesions.

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6056238

A quantitative analysis of oligodendrocytes in multiple sclerosis lesions. A study of 113 cases

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6056238

Synergistic signaling in fetal brain by STAT3-Smad1 complex bridged by p300

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6056238

Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6056238

Remyelination in multiple sclerosis

2 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29979149

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Differentiation block of oligodendroglial progenitor cells as a cause for remyelination failure in chronic multiple sclerosis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29979149

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.7554/ELIFE.35136

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29979149%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29979149%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

1 reference