Mn Porphyrin-Based Redox-Active Drugs: Differential Effects as Cancer Therapeutics and Protectors of Normal Tissue Against Oxidative Injury (Q57167081)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29926755%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

title

Mn Porphyrin-Based Redox-Active Drugs: Differential Effects as Cancer Therapeutics and Protectors of Normal Tissue Against Oxidative Injury (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29926755%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

1

Ines Batinic-Haberle

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29926755%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

author name string

Artak Tovmasyan

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29926755%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

Ivan Spasojevic

series ordinal

3

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1 April 2020

language of work or name

English

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publication date

28 August 2018

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29926755%20AND%20SRC:MED&resulttype=core&format=json

Antioxidants & Redox Signaling

1 April 2020

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29926755%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

volume

29

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1 April 2020

issue

16

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1 April 2020

page(s)

1691-1724

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Transition metals as catalysts of "autoxidation" reactions

1 April 2020

cites work

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12 December 2020

Chemical properties of water-soluble porphyrins. 5. Reactions of some manganese (III) porphyrins with the superoxide and other reducing radicals

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12 December 2020

Stable Mn(III) porphyrins mimic superoxide dismutase in vitro and substitute for it in vivo

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12 December 2020

A potent superoxide dismutase mimic: manganese beta-octabromo-meso-tetrakis-(N-methylpyridinium-4-yl) porphyrin

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12 December 2020

The ortho effect makes manganese(III) meso-tetrakis(N-methylpyridinium-2-yl)porphyrin a powerful and potentially useful superoxide dismutase mimic

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The nuclear factor-kappa B RelA transcription factor is constitutively activated in human pancreatic adenocarcinoma cells

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Catalytic scavenging of peroxynitrite by isomeric Mn(III) N-methylpyridylporphyrins in the presence of reductants

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A new temperature-sensitive liposome for use with mild hyperthermia: characterization and testing in a human tumor xenograft model

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Nitrosylation of manganese(II) tetrakis(N-ethylpyridinium-2-yl)porphyrin: a simple and sensitive spectrophotometric assay for nitric oxide

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Manganese(III) biliverdin IX dimethyl ester: a powerful catalytic scavenger of superoxide employing the Mn(III)/Mn(IV) redox couple

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Neuroprotection from delayed postischemic administration of a metalloporphyrin catalytic antioxidant.

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Overexpression of manganese superoxide dismutase suppresses tumor formation by modulation of activator protein-1 signaling in a multistage skin carcinogenesis model.

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Dependence of excitotoxic neurodegeneration on mitochondrial aconitase inactivation

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12 December 2020

Glutathionylation of the p50 subunit of NF-kappaB: a mechanism for redox-induced inhibition of DNA binding

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12 December 2020

A metalloporphyrin-based superoxide dismutase mimic inhibits adoptive transfer of autoimmune diabetes by a diabetogenic T-cell clone

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12 December 2020

Reactions of manganese porphyrins and manganese-superoxide dismutase with peroxynitrite

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12 December 2020

A small molecular weight catalytic metalloporphyrin antioxidant with superoxide dismutase (SOD) mimetic properties protects lungs from radiation-induced injury.

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12 December 2020

Electrostatic contribution in the catalysis of O2*- dismutation by superoxide dismutase mimics. MnIIITE-2-PyP5+ versus MnIIIBr8T-2-PyP+.

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Free radical stress in chronic lymphocytic leukemia cells and its role in cellular sensitivity to ROS-generating anticancer agents

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12 December 2020

Reactions of Manganese Porphyrins with Peroxynitrite and Carbonate Radical Anion

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12 December 2020

Tumor necrosis factor-alpha causes accumulation of a ubiquitinated form of hypoxia inducible factor-1alpha through a nuclear factor-kappaB-dependent pathway

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12 December 2020

Flavin-dependent antioxidant properties of a new series of meso-N,N'-dialkyl-imidazolium substituted manganese(III) porphyrins

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12 December 2020

Mechanistic analysis of the immunomodulatory effects of a catalytic antioxidant on antigen-presenting cells: implication for their use in targeting oxidation-reduction reactions in innate immunity

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12 December 2020

Radiation activates HIF-1 to regulate vascular radiosensitivity in tumors: role of reoxygenation, free radicals, and stress granules

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12 December 2020

Tetrahydrobiopterin rapidly reduces the SOD mimic Mn(III) ortho-tetrakis(N-ethylpyridinium-2-yl)porphyrin

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12 December 2020

Hepatocyte growth factor-activated NF-kappaB regulates HIF-1 activity and ODC expression, implicated in survival, differently in different carcinoma cell lines.

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12 December 2020

New class of potent catalysts of O2.-dismutation. Mn(III) ortho-methoxyethylpyridyl- and di-ortho-methoxyethylimidazolylporphyrins

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12 December 2020

A mechanism-based antioxidant approach for the reduction of skin carcinogenesis

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12 December 2020

A manganese porphyrin suppresses oxidative stress and extends the life span of streptozotocin-diabetic rats

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12 December 2020

In vitro modeling of human pancreatic duct epithelial cell transformation defines gene expression changes induced by K-ras oncogenic activation in pancreatic carcinogenesis

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12 December 2020

Pharmacologic ascorbic acid concentrations selectively kill cancer cells: action as a pro-drug to deliver hydrogen peroxide to tissues

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12 December 2020

A manganese porphyrin superoxide dismutase mimetic enhances tumor radioresponsiveness.

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12 December 2020

A glutathione S-transferase pi-activated prodrug causes kinase activation concurrent with S-glutathionylation of proteins

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12 December 2020

Lymphatic or hematogenous dissemination: how does a metastatic tumor cell decide?

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12 December 2020

New approach to the activation of anti-cancer pro-drugs by metalloporphyrin-based cytochrome P450 mimics in all-aqueous biologically relevant system

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12 December 2020

Redox-sensitive kinases of the nuclear factor-kappaB signaling pathway

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12 December 2020

YC-1 inhibits HIF-1 expression in prostate cancer cells: contribution of Akt/NF-kappaB signaling to HIF-1alpha accumulation during hypoxia

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12 December 2020

Long-term administration of a small molecular weight catalytic metalloporphyrin antioxidant, AEOL 10150, protects lungs from radiation-induced injury

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12 December 2020

Reactive oxygen species activate the HIF-1alpha promoter via a functional NFkappaB site

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12 December 2020

Mn porphyrin-based superoxide dismutase (SOD) mimic, MnIIITE-2-PyP5+, targets mouse heart mitochondria

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12 December 2020

Manganese porphyrin reduces renal injury and mitochondrial damage during ischemia/reperfusion.

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12 December 2020

Low molecular weight catalytic metalloporphyrin antioxidant AEOL 10150 protects lungs from fractionated radiation

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12 December 2020

Comparison of two Mn porphyrin-based mimics of superoxide dismutase in pulmonary radioprotection

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12 December 2020

Pulse radiolysis investigation on the mechanism of the catalytic action of Mn(II)-pentaazamacrocycle compounds as superoxide dismutase mimetics

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12 December 2020

SOD-like activity of Mn(II) beta-octabromo-meso-tetrakis(N-methylpyridinium-3-yl)porphyrin equals that of the enzyme itself

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12 December 2020

Pharmacokinetics of the potent redox-modulating manganese porphyrin, MnTE-2-PyP(5+), in plasma and major organs of B6C3F1 mice

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12 December 2020

NO dismutase activity of seven-coordinate manganese(II) pentaazamacrocyclic complexes

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12 December 2020

Lipophilicity is a critical parameter that dominates the efficacy of metalloporphyrins in blocking the development of morphine antinociceptive tolerance through peroxynitrite-mediated pathways

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12 December 2020

Pure MnTBAP selectively scavenges peroxynitrite over superoxide: comparison of pure and commercial MnTBAP samples to MnTE-2-PyP in two models of oxidative stress injury, an SOD-specific Escherichia coli model and carrageenan-induced pleurisy.

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12 December 2020

Redox regulation of nuclear post-translational modifications during NF-kappaB activation

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12 December 2020

Radioprotective effects of manganese-containing superoxide dismutase mimics on ataxia-telangiectasia cells.

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12 December 2020

Hypoxia activates NF-kappaB-dependent gene expression through the canonical signaling pathway

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12 December 2020

Increased manganese superoxide dismutase expression or treatment with manganese porphyrin potentiates dexamethasone-induced apoptosis in lymphoma cells

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12 December 2020

Antiangiogenic action of redox-modulating Mn(III) meso-tetrakis(N-ethylpyridinium-2-yl)porphyrin, MnTE-2-PyP(5+), via suppression of oxidative stress in a mouse model of breast tumor

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12 December 2020

Supraspinal inactivation of mitochondrial superoxide dismutase is a source of peroxynitrite in the development of morphine antinociceptive tolerance

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12 December 2020

Long-term neuroprotection from a potent redox-modulating metalloporphyrin in the rat.

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12 December 2020

Superoxide dismutase activity of corrole metal complexes

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12 December 2020

KEAP1 E3 ligase-mediated downregulation of NF-kappaB signaling by targeting IKKbeta

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12 December 2020

High lipophilicity of meta Mn(III) N-alkylpyridylporphyrin-based superoxide dismutase mimics compensates for their lower antioxidant potency and makes them as effective as ortho analogues in protecting superoxide dismutase-deficient Escherichia coli

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12 December 2020

Superoxide dismutase mimics: chemistry, pharmacology, and therapeutic potential

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12 December 2020

Early and late administration of MnTE-2-PyP5+ in mitigation and treatment of radiation-induced lung damage

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12 December 2020

Reactive oxygen species in cancer

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12 December 2020

Design of Mn porphyrins for treating oxidative stress injuries and their redox-based regulation of cellular transcriptional activities

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12 December 2020

Oxidative stress, inflammation, and cancer: how are they linked?

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12 December 2020

AEOL10150: a novel therapeutic for rescue treatment after toxic gas lung injury

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12 December 2020

Methoxy-derivatization of alkyl chains increases the in vivo efficacy of cationic Mn porphyrins. Synthesis, characterization, SOD-like activity, and SOD-deficient E. coli study of meta Mn(III) N-methoxyalkylpyridylporphyrins.

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12 December 2020

NADPH oxidase inhibition attenuates total body irradiation-induced haematopoietic genomic instability

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12 December 2020

Mn(III) meso-tetrakis-(N-ethylpyridinium-2-yl) porphyrin mitigates total body irradiation-induced long-term bone marrow suppression

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12 December 2020

NADPH oxidase-derived superoxide anion-induced apoptosis is mediated via the JNK-dependent activation of NF-κB in cardiomyocytes exposed to high glucose

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12 December 2020

Diverse functions of cationic Mn(III) N-substituted pyridylporphyrins, recognized as SOD mimics

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12 December 2020

Neuroprotective efficacy from a lipophilic redox-modulating Mn(III) N-Hexylpyridylporphyrin, MnTnHex-2-PyP: rodent models of ischemic stroke and subarachnoid hemorrhage

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12 December 2020

Manganese porphyrin reduces retinal injury induced by ocular hypertension in rats

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12 December 2020

Cytotoxic effects of Mn(III) N-alkylpyridylporphyrins in the presence of cellular reductant, ascorbate

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12 December 2020

Manganese superoxide dismutase is a mitochondrial fidelity protein that protects Polγ against UV-induced inactivation

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12 December 2020

Amelioration of Renal Ischemia-Reperfusion Injury With a Novel Protective Cocktail

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12 December 2020

Manganese superoxide dismutase, MnSOD and its mimics

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12 December 2020

Cysteine 38 holds the key to NF-κB activation

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12 December 2020

Oxidative stress mediates radiation lung injury by inducing apoptosis.

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12 December 2020

Manganese porphyrin, MnTE-2-PyP5+, Acts as a pro-oxidant to potentiate glucocorticoid-induced apoptosis in lymphoma cells

1 reference

12 December 2020

A new SOD mimic, Mn(III) ortho N-butoxyethylpyridylporphyrin, combines superb potency and lipophilicity with low toxicity

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12 December 2020

Motor deficits are triggered by reperfusion-reoxygenation injury as diagnosed by MRI and by a mechanism involving oxidants

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12 December 2020

Fine tuning the reactivity of corrole-based catalytic antioxidants

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12 December 2020

Overcoming limitations in nanoparticle drug delivery: triggered, intravascular release to improve drug penetration into tumors

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12 December 2020

The antioxidant, MnTE-2-PyP, prevents side-effects incurred by prostate cancer irradiation

1 reference

12 December 2020

Design, mechanism of action, bioavailability and therapeutic effects of mn porphyrin-based redox modulators.

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12 December 2020

The administration of renoprotective agents extends warm ischemia in a rat model

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12 December 2020

The Nrf2 cell defence pathway: Keap1-dependent and -independent mechanisms of regulation

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12 December 2020

Transcriptional regulation of ncx1 gene in the brain

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12 December 2020

Comprehensive pharmacokinetic studies and oral bioavailability of two Mn porphyrin-based SOD mimics, MnTE-2-PyP5+ and MnTnHex-2-PyP5+.

1 reference

12 December 2020

Pharmacological ascorbate with gemcitabine for the control of metastatic and node-positive pancreatic cancer (PACMAN): results from a phase I clinical trial.

1 reference

12 December 2020

Differential coordination demands in Fe versus Mn water-soluble cationic metalloporphyrins translate into remarkably different aqueous redox chemistry and biology.

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12 December 2020

A nonclinical safety assessment of MnTE-2-PyP, a manganese porphyrin

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12 December 2020

Metalloporphyrins as therapeutic catalytic oxidoreductants in central nervous system disorders.

1 reference

12 December 2020

Nanoscale Drug Delivery and Hyperthermia: The Materials Design and Preclinical and Clinical Testing of Low Temperature-Sensitive Liposomes Used in Combination with Mild Hyperthermia in the Treatment of Local Cancer

1 reference

12 December 2020

SOD therapeutics: latest insights into their structure-activity relationships and impact on the cellular redox-based signaling pathways

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12 December 2020

Manganese superoxide dismutase is a promising target for enhancing chemosensitivity of basal-like breast carcinoma.

1 reference

12 December 2020

Late administration of Mn porphyrin-based SOD mimic enhances diabetic complications

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12 December 2020

Effect of molecular characteristics on cellular uptake, subcellular localization, and phototoxicity of Zn(II) N-alkylpyridylporphyrins.

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12 December 2020

Mn porphyrin in combination with ascorbate acts as a pro-oxidant and mediates caspase-independent cancer cell death

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12 December 2020

Superoxide dismutase mimic, MnTE-2-PyP(5+) ameliorates acute and chronic proctitis following focal proton irradiation of the rat rectum

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12 December 2020

Robust rat pulmonary radioprotection by a lipophilic Mn N-alkylpyridylporphyrin, MnTnHex-2-PyP(5+).

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12 December 2020

Catalytic antioxidant AEOL 10150 treatment ameliorates sulfur mustard analog 2-chloroethyl ethyl sulfide-associated cutaneous toxic effects

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12 December 2020

Mn porphyrin-based SOD mimic, MnTnHex-2-PyP(5+), and non-SOD mimic, MnTBAP(3-), suppressed rat spinal cord ischemia/reperfusion injury via NF-κB pathways

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12 December 2020

Can nitroxides evoke the Keap1-Nrf2-ARE pathway in skin?

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12 December 2020

Radioprotection of the brain white matter by Mn(III) n-Butoxyethylpyridylporphyrin-based superoxide dismutase mimic MnTnBuOE-2-PyP5+.

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12 December 2020

Rational design of superoxide dismutase (SOD) mimics: the evaluation of the therapeutic potential of new cationic Mn porphyrins with linear and cyclic substituents

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12 December 2020

Differential localization and potency of manganese porphyrin superoxide dismutase-mimicking compounds in Saccharomyces cerevisiae

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12 December 2020

HIF-1α restricts NF-κB-dependent gene expression to control innate immunity signals

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12 December 2020

Manganese (III) meso-tetrakis N-ethylpyridinium-2-yl porphyrin acts as a pro-oxidant to inhibit electron transport chain proteins, modulate bioenergetics, and enhance the response to chemotherapy in lymphoma cells

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12 December 2020

Temporal regulation of HIF-1 and NF-κB in hypoxic hepatocarcinoma cells.

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12 December 2020

An educational overview of the chemistry, biochemistry and therapeutic aspects of Mn porphyrins--From superoxide dismutation to H2O2-driven pathways

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12 December 2020

A comprehensive evaluation of catalase-like activity of different classes of redox-active therapeutics

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12 December 2020

Pharmacological Ascorbate Radiosensitizes Pancreatic Cancer

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12 December 2020

Manganese [III] Tetrakis [5,10,15,20]-Benzoic Acid Porphyrin Reduces Adiposity and Improves Insulin Action in Mice with Pre-Existing Obesity

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12 December 2020

Dose Optimization Study of AEOL 10150 as a Mitigator of Radiation-Induced Lung Injury in CBA/J Mice

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12 December 2020

Redox-Active Mn Porphyrin-based Potent SOD Mimic, MnTnBuOE-2-PyP(5+), Enhances Carbenoxolone-Mediated TRAIL-Induced Apoptosis in Glioblastoma Multiforme.

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12 December 2020

Antioxidants as potential medical countermeasures for chemical warfare agents and toxic industrial chemicals

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12 December 2020

Anticancer therapeutic potential of Mn porphyrin/ascorbate system

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12 December 2020

Novel Manganese-Porphyrin Superoxide Dismutase-Mimetic Widens the Therapeutic Margin in a Preclinical Head and Neck Cancer Model

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12 December 2020

Dysregulation of the Keap1-Nrf2 pathway in cancer

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12 December 2020

Novel role of 4-hydroxy-2-nonenal in AIFm2-mediated mitochondrial stress signaling.

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12 December 2020

Synthetic Lethality of a Novel Small Molecule Against Mutant KRAS-Expressing Cancer Cells Involves AKT-Dependent ROS Production

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12 December 2020

Opinion on Schmidt et al

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12 December 2020

MnTE-2-PyP reduces prostate cancer growth and metastasis by suppressing p300 activity and p300/HIF-1/CREB binding to the promoter region of the PAI-1 gene

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12 December 2020

S-Glutathionylation of Keap1: a new role for glutathione S-transferase pi in neuronal protection.

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12 December 2020

Nonclinical Safety and Toxicokinetics of MnTnBuOE-2-PyP5+ (BMX-001).

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12 December 2020

MnTnBuOE-2-PyP protects normal colorectal fibroblasts from radiation damage and simultaneously enhances radio/chemotherapeutic killing of colorectal cancer cells

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12 December 2020

A novel redox-active metalloporphyrin reduces reactive oxygen species and inflammatory markers but does not improve marginal mass engraftment in a murine donation after circulatory death islet transplantation model

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12 December 2020

Neurobehavioral radiation mitigation to standard brain cancer therapy regimens by Mn(III) n-butoxyethylpyridylporphyrin-based redox modifier

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12 December 2020

Curcumin alleviates lipopolysaccharide induced sepsis and liver failure by suppression of oxidative stress-related inflammation via PI3K/AKT and NF-κB related signaling

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12 December 2020

Manganese Superoxide Dismutase Expression Regulates the Switch Between an Epithelial and a Mesenchymal-Like Phenotype in Breast Carcinoma

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12 December 2020

Targeting Nrf2 with wogonin overcomes cisplatin resistance in head and neck cancer

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12 December 2020

Curcumin prevents muscle damage by regulating NF-κB and Nrf2 pathways and improves performance: an in vivo model.

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12 December 2020

MnTE-2-PyP modulates thiol oxidation in a hydrogen peroxide-mediated manner in a human prostate cancer cell

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12 December 2020

Topically applied manganese-porphyrins BMX-001 and BMX-010 display a significant anti-inflammatory response in a mouse model of allergic dermatitis

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12 December 2020

Tumor cells have decreased ability to metabolize H2O2: Implications for pharmacological ascorbate in cancer therapy

1 reference

12 December 2020

Protective effects of curcumin against mercury-induced hepatic injuries in rats, involvement of oxidative stress antagonism, and Nrf2-ARE pathway activation

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12 December 2020

Optimizing Zn porphyrin-based photosensitizers for efficient antibacterial photodynamic therapy.

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12 December 2020

Oxidative stress in cancer and fibrosis: Opportunity for therapeutic intervention with antioxidant compounds, enzymes, and nanoparticles

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12 December 2020

Bioactive Flavonoids and Catechols as Hif1 and Nrf2 Protein Stabilizers - Implications for Parkinson's Disease

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12 December 2020

Manganese superoxide dismutase and glutathione peroxidase-1 contribute to the rise and fall of mitochondrial reactive oxygen species which drive oncogenesis

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12 December 2020

Challenges encountered during development of Mn porphyrin-based, potent redox-active drug and superoxide dismutase mimic, MnTnBuOE-2-PyP5+, and its alkoxyalkyl analogues.

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12 December 2020

AEOL 10150 Mitigates Radiation-Induced Lung Injury in the Nonhuman Primate: Morbidity and Mortality are Administration Schedule-Dependent

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12 December 2020

MnTE-2-PyP Treatment, or NOX4 Inhibition, Protects against Radiation-Induced Damage in Mouse Primary Prostate Fibroblasts by Inhibiting the TGF-Beta 1 Signaling Pathway

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12 December 2020

A novel redox regulator, MnTnBuOE-2-PyP5+, enhances normal hematopoietic stem/progenitor cell function

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12 December 2020

Reactive Oxygen and Nitrogen Species in Carcinogenesis: Implications of Oxidative Stress on the Progression and Development of Several Cancer Types

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12 December 2020

Mechanism of the Antitumor and Radiosensitizing Effects of a Manganese Porphyrin, MnHex-2-PyP.

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12 December 2020

ROS in Cancer: The Burning Question

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12 December 2020

Ionizing radiation induces long-term senescence in endothelial cells through mitochondrial respiratory complex II dysfunction and superoxide generation.

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12 December 2020

CNS bioavailability and radiation protection of normal hippocampal neurogenesis by a lipophilic Mn porphyrin-based superoxide dismutase mimic, MnTnBuOE-2-PyP5.

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12 December 2020

Oxidative Stress Contributes to Status Epilepticus Associated Mortality

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12 December 2020

Cellular Fates of Manganese(II) Pentaazamacrocyclic Superoxide Dismutase (SOD) Mimetics: Fluorescently Labeled MnSOD Mimetics, X-ray Absorption Spectroscopy, and X-ray Fluorescence Microscopy Studies.

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12 December 2020

Inhibition of the Continuum of Radiation-Induced Normal Tissue Injury by a Redox-Active Mn Porphyrin

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12 December 2020

Potential for a novel manganese porphyrin compound as adjuvant canine lymphoma therapy

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12 December 2020

Differential impact of flavonoids on redox modulation, bioenergetics and cell signalling in normal and tumor cells: a comprehensive review

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12 December 2020

Reduction-oxidation pathways involved in cancer development: a systematic review of literature reviews

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12 December 2020

Hematopoietic Stem Cells: Normal Versus Malignant.

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12 December 2020

Mitochondria-Centric Review of Polyphenol Bioactivity in Cancer Models.

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12 December 2020

Treatment with a Catalytic Superoxide Dismutase (SOD) Mimetic Improves Liver Steatosis, Insulin Sensitivity, and Inflammation in Obesity-Induced Type 2 Diabetes.

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12 December 2020

The SOD Mimic, MnTE-2-PyP, Protects from Chronic Fibrosis and Inflammation in Irradiated Normal Pelvic Tissues

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12 December 2020

Modulators of Redox Metabolism in Head and Neck Cancer.

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12 December 2020

Phase 1b/2a Trial of the Superoxide Dismutase Mimetic GC4419 to Reduce Chemoradiotherapy-Induced Oral Mucositis in Patients With Oral Cavity or Oropharyngeal Carcinoma.

1 reference

12 December 2020

Reactive Oxygen Species and Oncoprotein Signaling-A Dangerous Liaison

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12 December 2020

Superoxide Dismutase Mimetic GC4419 Enhances the Oxidation of Pharmacological Ascorbate and Its Anticancer Effects in an H₂O₂-Dependent Manner.

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12 December 2020

Role of mitochondrial oxidative stress in modulating the expressions of aquaporins in obstructive kidney disease.

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12 December 2020

The Addition of Manganese Porphyrins during Radiation Inhibits Prostate Cancer Growth and Simultaneously Protects Normal Prostate Tissue from Radiation Damage

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12 December 2020

Radiation-mediated tumor growth inhibition is significantly enhanced with redox-active compounds that cycle with ascorbate

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12 December 2020

BMX-001, a novel redox-active metalloporphyrin, improves islet function and engraftment in a murine transplant model.

1 reference

12 December 2020

Post-Irradiation Treatment with a Superoxide Dismutase Mimic, MnTnHex-2-PyP5+, Mitigates Radiation Injury in the Lungs of Non-Human Primates after Whole-Thorax Exposure to Ionizing Radiation.

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12 December 2020

Identification of an Unfavorable Immune Signature in Advanced Lung Tumors from Nrf2-Deficient Mice.

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12 December 2020

INK4a/ARF Expression Impairs Neurogenesis in the Brain of Irradiated Mice.

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12 December 2020

Porphyrin-Based SOD Mimic MnTnBu OE -2-PyP Inhibits Mechanisms of Aortic Valve Remodeling in Human and Murine Models of Aortic Valve Sclerosis

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12 December 2020

Identifiers

DOI

10.1089/ARS.2017.7453

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29926755%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29926755%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

PubMed publication ID

29926755

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