Activation of ARF by oncogenic stress in mouse fibroblasts is independent of E2F1 and E2F2 (Q57562816)

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

p14ARF links the tumour suppressors RB and p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

Transcription factor E2F-1 is upregulated in response to DNA damage in a manner analogous to that of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

Ablation of the retinoblastoma gene family deregulates G(1) control causing immortalization and increased cell turnover under growth-restricting conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

E1A signaling to p53 involves the p19(ARF) tumor suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

Distinct roles for E2F proteins in cell growth control and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

Regulation of a senescence checkpoint response by the E2F1 transcription factor and p14(ARF) tumor suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

The regulation of E2F by pRB-family proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

Human ARF binds E2F1 and inhibits its transcriptional activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

The Rb/E2F pathway: expanding roles and emerging paradigms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

Increased levels of E2F-1-dependent DNA binding activity after UV- or gamma-irradiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

Novel function of the cyclin A binding site of E2F in regulating p53-induced apoptosis in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

Induction of ARF tumor suppressor gene expression and cell cycle arrest by transcription factor DMP1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

Role for the p53 homologue p73 in E2F-1-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

Role for E2F in control of both DNA replication and mitotic functions as revealed from DNA microarray analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

Tumor spectrum analysis in p53-mutant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

Senescence bypass screen identifies TBX2, which represses Cdkn2a (p19(ARF)) and is amplified in a subset of human breast cancers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

The tumorigenic potential and cell growth characteristics of p53-deficient cells are equivalent in the presence or absence of Mdm2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

Loss of p16Ink4a confers susceptibility to metastatic melanoma in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

A common E2F-1 and p73 pathway mediates cell death induced by TCR activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

Stabilization of p53 by p14ARF without relocation of MDM2 to the nucleolus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

Stabilization of the p53 tumor suppressor is induced by adenovirus 5 E1A and accompanies apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

Twist is a potential oncogene that inhibits apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

p19ARF targets certain E2F species for degradation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

Apaf-1 is a transcriptional target for E2F and p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

E2Fs regulate the expression of genes involved in differentiation, development, proliferation, and apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

Accumulation of p16INK4a in mouse fibroblasts as a function of replicative senescence and not of retinoblastoma gene status

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

p19ARF links the tumour suppressor p53 to Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

Induction of senescence by oncogenic Ras.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

Key roles for E2F1 in signaling p53-dependent apoptosis and in cell division within developing tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

Murine fibroblasts lacking p21 undergo senescence and are resistant to transformation by oncogenic Ras.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

Escape from premature senescence is not sufficient for oncogenic transformation by Ras.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

Induction of DNA synthesis and apoptosis are separable functions of E2F-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

E2F-1 potentiates cell death by blocking antiapoptotic signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

p19(Arf) induces p53-dependent apoptosis during abelson virus-mediated pre-B cell transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

Loss of E2F4 activity leads to abnormal development of multiple cellular lineages

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

The human ARF cell cycle regulatory gene promoter is a CpG island which can be silenced by DNA methylation and down-regulated by wild-type p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

The tumor suppressor protein p16INK4a.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

The INK4a/ARF locus in murine tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

Role of the INK4a locus in tumor suppression and cell mortality.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

Loss of p16Ink4a with retention of p19Arf predisposes mice to tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

The INK4A/ARF locus and its two gene products

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

Tumor surveillance via the ARF-p53 pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

The INK4a/ARF network in tumour suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

Parsing Ink4a/Arf: "pure" p16-null mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

Cellular senescence: mitotic clock or culture shock?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

Quantitative studies of the growth of mouse embryo cells in culture and their development into established lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

p19(ARF) is dispensable for oncogenic stress-induced p53-mediated apoptosis and tumor suppression in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

Sibling rivalry in the E2F family

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

CDC25A phosphatase is a target of E2F and is required for efficient E2F-induced S phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

21 January 2018

Surfing the p53 network

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

The cat and mouse games that genes, viruses, and cells play

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

JunD protects cells from p53-dependent senescence and apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

Regulation of p53 function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

The E2F1-3 transcription factors are essential for cellular proliferation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

E2F1 and E2F2 determine thresholds for antigen-induced T-cell proliferation and suppress tumorigenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

E2F3 contributes both to the inappropriate proliferation and to the apoptosis arising in Rb mutant embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

Expression of the p16INK4a tumor suppressor versus other INK4 family members during mouse development and aging.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

Mutation of E2F2 in Mice Causes Enhanced T Lymphocyte Proliferation, Leading to the Development of Autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

E2F-1 functions in mice to promote apoptosis and suppress proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

7 January 2021

E2F1 overexpression in quiescent fibroblasts leads to induction of cellular DNA synthesis and apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

7 January 2021

Myc requires distinct E2F activities to induce S phase and apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

7 January 2021

Signaling to p53: breaking the MDM2-p53 circuit

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

7 January 2021

The p16INK4a/CDKN2A tumor suppressor and its relatives.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

7 January 2021

Differential regulation of the p21/WAF-1 and mdm2 genes after high-dose UV irradiation: p53-dependent and p53-independent regulation of the mdm2 gene.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

7 January 2021

Tumor induction and tissue atrophy in mice lacking E2F-1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205371

7 January 2021