A systems-wide screen identifies substrates of the SCF TrCP ubiquitin ligase (Q57666020)

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25 February 2020

title

A systems-wide screen identifies substrates of the SCFβTrCP ubiquitin ligase (English)

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25 February 2020

1

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25 February 2020

Mao Peng

2

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25 February 2020

Shabaz Mohammed

4

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25 February 2020

Daniele Guardavaccaro

5

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25 February 2020

Albert J.R. Heck

6

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25 February 2020

author name string

Roberto Magliozzi

3

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25 February 2020

publication date

16 December 2014

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25 February 2020

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25 February 2020

volume

7

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25 February 2020

page(s)

rs8

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issue

356

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Ubiquitin-binding domains - from structures to functions

25 February 2020

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SCFbetaTrCP-mediated degradation of Claspin regulates recovery from the DNA replication checkpoint response

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S6K1- and betaTRCP-mediated degradation of PDCD4 promotes protein translation and cell growth

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Control of chromosome stability by the beta-TrCP-REST-Mad2 axis

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Understanding cullin-RING E3 biology through proteomics-based substrate identification

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betaTrCP- and Rsk1/2-mediated degradation of BimEL inhibits apoptosis

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Structure of a beta-TrCP1-Skp1-beta-catenin complex: destruction motif binding and lysine specificity of the SCF(beta-TrCP1) ubiquitin ligase

21 January 2018

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The SCFbeta-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkappaBalpha and beta-catenin and stimulates IkappaBalpha ubiquitination in vitro

21 January 2018

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Coupled activation and degradation of eEF2K regulates protein synthesis in response to genotoxic stress

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Deregulated proteolysis by the F-box proteins SKP2 and beta-TrCP: tipping the scales of cancer

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21 January 2018

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MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

21 January 2018

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A practical guide to the MaxQuant computational platform for SILAC-based quantitative proteomics

21 January 2018

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Andromeda: a peptide search engine integrated into the MaxQuant environment

21 January 2018

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Extracting gene function from protein-protein interactions using Quantitative BAC InteraCtomics (QUBIC).

21 January 2018

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Repo-Man recruits PP1 gamma to chromatin and is essential for cell viability

21 January 2018

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A proteomics strategy to elucidate functional protein-protein interactions applied to EGF signaling

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21 January 2018

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QuasiMotiFinder: protein annotation by searching for evolutionarily conserved motif-like patterns

21 January 2018

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Masking residues using context-specific evolutionary conservation significantly improves short linear motif discovery.

21 January 2018

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Identification of enriched PTM crosstalk motifs from large-scale experimental data sets.

21 January 2018

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Control of epithelial cell migration and invasion by the IKKβ- and CK1α-mediated degradation of RAPGEF2.

21 January 2018

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Proteasome-dependent degradation of transcription factor activating enhancer-binding protein 4 (TFAP4) controls mitotic division

21 January 2018

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Identification of the receptor component of the IkappaBalpha-ubiquitin ligase

21 January 2018

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A novel human WD protein, h-beta TrCp, that interacts with HIV-1 Vpu connects CD4 to the ER degradation pathway through an F-box motif

21 January 2018

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Accurate proteome-wide label-free quantification by delayed normalization and maximal peptide ratio extraction, termed MaxLFQ.

21 January 2018

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USP17- and SCFβTrCP--regulated degradation of DEC1 controls the DNA damage response

21 January 2018

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PDZ-GEF1, a guanine nucleotide exchange factor specific for Rap1 and Rap2

21 January 2018

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21 January 2018

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nRap GEP: a novel neural GDP/GTP exchange protein for rap1 small G protein that interacts with synaptic scaffolding molecule (S-SCAM)

21 January 2018

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Characterization of the role of the Rab GTPase-activating protein AS160 in insulin-regulated GLUT4 trafficking

21 January 2018

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AS160, the Akt substrate regulating GLUT4 translocation, has a functional Rab GTPase-activating protein domain

21 January 2018

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21 January 2018

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21 January 2018

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Quantitative proteomics combined with BAC TransgeneOmics reveals in vivo protein interactions

21 January 2018

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MEME SUITE: tools for motif discovery and searching

21 January 2018

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FIMO: scanning for occurrences of a given motif

21 January 2018

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eggNOG: automated construction and annotation of orthologous groups of genes

21 January 2018

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Negative regulation of prolactin receptor stability and signaling mediated by SCF(beta-TrCP) E3 ubiquitin ligase

21 January 2018

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Dual regulation of Snail by GSK-3beta-mediated phosphorylation in control of epithelial-mesenchymal transition

21 January 2018

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ATF4 degradation relies on a phosphorylation-dependent interaction with the SCF(betaTrCP) ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005882

DNA damage regulates UHRF1 stability via the SCF(β-TrCP) E3 ligase

21 January 2018

1 reference

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Plk1 regulates activation of the anaphase promoting complex by phosphorylating and triggering SCFbetaTrCP-dependent destruction of the APC Inhibitor Emi1

21 January 2018

1 reference

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SCFbeta-TRCP links Chk1 signaling to degradation of the Cdc25A protein phosphatase

21 January 2018

1 reference

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Mechanism of processing of the NF-kappa B2 p100 precursor: identification of the specific polyubiquitin chain-anchoring lysine residue and analysis of the role of NEDD8-modification on the SCF(beta-TrCP) ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005882

Regulated degradation of FANCM in the Fanconi anemia pathway during mitosis

21 January 2018

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A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP)

21 January 2018

1 reference

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SCFbeta-TRCP controls clock-dependent transcription via casein kinase 1-dependent degradation of the mammalian period-1 (Per1) protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005882

Nrf2 is controlled by two distinct β-TrCP recognition motifs in its Neh6 domain, one of which can be modulated by GSK-3 activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005882

The FWD1/beta-TrCP-mediated degradation pathway establishes a 'turning off switch' of a Cdc42 guanine nucleotide exchange factor, FGD1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005882

The role of {beta}-TrCP1 and {beta}-TrCP2 in circadian rhythm generation by mediating degradation of clock protein PER2

21 January 2018

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Beta-TrCP1-mediated degradation of PERIOD2 is essential for circadian dynamics

21 January 2018

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βTrCP controls GH receptor degradation via two different motifs

21 January 2018

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DEPTOR, an mTOR inhibitor, is a physiological substrate of SCF(βTrCP) E3 ubiquitin ligase and regulates survival and autophagy

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005882

Skp1-Cul1-F-box ubiquitin ligase (SCF(βTrCP))-mediated destruction of the ubiquitin-specific protease USP37 during G2-phase promotes mitotic entry

21 January 2018

1 reference

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SCFHOS ubiquitin ligase mediates the ligand-induced down-regulation of the interferon- receptor

21 January 2018

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M-phase kinases induce phospho-dependent ubiquitination of somatic Wee1 by SCFbeta-TrCP

21 January 2018

1 reference

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Thiazolidinediones mimic glucose starvation in facilitating Sp1 degradation through the up-regulation of beta-transducin repeat-containing protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005882

Ubiquitin-dependent degradation of IkappaBalpha is mediated by a ubiquitin ligase Skp1/Cul 1/F-box protein FWD1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005882

Plk1- and beta-TrCP-dependent degradation of Bora controls mitotic progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005882

The N-terminal phosphodegron targets TAZ/WWTR1 protein for SCFβ-TrCP-dependent degradation in response to phosphatidylinositol 3-kinase inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005882

The hippo tumor pathway promotes TAZ degradation by phosphorylating a phosphodegron and recruiting the SCF{beta}-TrCP E3 ligase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005882

beta-Trcp mediates ubiquitination and degradation of the erythropoietin receptor and controls cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005882

betaTrCP-mediated proteolysis of NF-kappaB1 p105 requires phosphorylation of p105 serines 927 and 932.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005882

Regulation of the discs large tumor suppressor by a phosphorylation-dependent interaction with the beta-TrCP ubiquitin ligase receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005882

Mechanism of degradation of CPEB during Xenopus oocyte maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005882

Regulation of postsynaptic RapGAP SPAR by Polo-like kinase 2 and the SCFbeta-TRCP ubiquitin ligase in hippocampal neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005882

Plk4 trans-autophosphorylation regulates centriole number by controlling betaTrCP-mediated degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005882

SCF-mediated Cdh1 degradation defines a negative feedback system that coordinates cell-cycle progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005882

Ubiquitylation of the amino terminus of Myc by SCF(β-TrCP) antagonizes SCF(Fbw7)-mediated turnover

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005882

Hsp27 and F-box protein β-TrCP promote degradation of mRNA decay factor AUF1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005882

Beta-TrCP recognizes a previously undescribed nonphosphorylated destruction motif in Cdc25A and Cdc25B phosphatases

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005882

Phosphorylation by casein kinase I promotes the turnover of the Mdm2 oncoprotein via the SCF(beta-TRCP) ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005882

Degradation of Mcl-1 by beta-TrCP mediates glycogen synthase kinase 3-induced tumor suppression and chemosensitization

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005882

The mRNA-stabilizing factor HuR protein is targeted by β-TrCP protein for degradation in response to glycolysis inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005882

NMR studies of the phosphorylation motif of the HIV-1 protein Vpu bound to the F-box protein beta-TrCP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005882

10.1126/SCISIGNAL.2005882

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25515538%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

1 reference