Interactome and Proteome Dynamics Uncover Immune Modulatory Associations of the Pathogen Sensing Factor cGAS (Q59350202)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30471916%20AND%20SRC:MED&resulttype=core&format=json

5 May 2020

author name string

Krystal K Lum

1

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5 May 2020

Bokai Song

2

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5 May 2020

Joel D Federspiel

3

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5 May 2020

Benjamin A Diner

4

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5 May 2020

Timothy Howard

5

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5 May 2020

Ileana M Cristea

6

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5 May 2020

language of work or name

English

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publication date

12 November 2018

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published in

Cell Systems

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5 May 2020

volume

7

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5 May 2020

issue

6

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5 May 2020

page(s)

627-642.e6

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describes a project that uses

5 May 2020

Cytoscape

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9 June 2022

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ImageJ

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11 June 2022

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Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity

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Cyclic GMP-AMP Synthase Is Activated by Double-Stranded DNA-Induced Oligomerization

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12 December 2020

The Cytosolic DNA Sensor cGAS Forms an Oligomeric Complex with DNA and Undergoes Switch-like Conformational Changes in the Activation Loop

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12 December 2020

Crosstalk between the cGAS DNA sensor and Beclin-1 autophagy protein shapes innate antimicrobial immune responses

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cGAS-mediated stabilization of IFI16 promotes innate signaling during herpes simplex virus infection

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PQBP1 Is a Proximal Sensor of the cGAS-Dependent Innate Response to HIV-1.

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cGAS Senses Human Cytomegalovirus and Induces Type I Interferon Responses in Human Monocyte-Derived Cells

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TRIM14 Inhibits cGAS Degradation Mediated by Selective Autophagy Receptor p62 to Promote Innate Immune Responses.

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Viral DNA Sensors IFI16 and Cyclic GMP-AMP Synthase Possess Distinct Functions in Regulating Viral Gene Expression, Immune Defenses, and Apoptotic Responses during Herpesvirus Infection

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TRIM56-mediated monoubiquitination of cGAS for cytosolic DNA sensing.

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The interferon-stimulated gene product oligoadenylate synthetase-like protein enhances replication of Kaposi's sarcoma-associated herpesvirus (KSHV) and interacts with the KSHV ORF20 protein.

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Species-Specific Deamidation of cGAS by Herpes Simplex Virus UL37 Protein Facilitates Viral Replication

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12 December 2020

10.1016/J.CELS.2018.10.010

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30471916%20AND%20SRC:MED&resulttype=core&format=json

5 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30471916%20AND%20SRC:MED&resulttype=core&format=json

5 May 2020

PubMed publication ID

30471916

1 reference