Choroid Plexus Megalin Is Involved in Neuroprotection by Serum Insulin-Like Growth Factor I (Q60693600)

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9 January 2020

title

Choroid plexus megalin is involved in neuroprotection by serum insulin-like growth factor I (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16306401%20AND%20SRC:MED&resulttype=core&format=json

insulin like growth factor 1 receptor

9 January 2020

main subject

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protein transporter activity

GOA release 2020-03-11

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GOA release 2020-03-11

author

Eva Carro

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16306401%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Carlos Spuch

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16306401%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Ignacio Torres Aleman

5

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16306401%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

author name string

Jose Luis Trejo

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16306401%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Desiré Antequera

4

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9 January 2020

language of work or name

English

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publication date

1 November 2005

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16306401%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

published in

Journal of Neuroscience

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16306401%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

volume

25

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9 January 2020

issue

47

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16306401%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

page(s)

10884-10893

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Peripheral infusion of IGF-I selectively induces neurogenesis in the adult rat hippocampus.

9 January 2020

cites work

1 reference

12 December 2020

Circulating insulin-like growth factor I mediates effects of exercise on the brain.

1 reference

12 December 2020

Cytosolic adaptor protein Dab2 is an intracellular ligand of endocytic receptor gp600/megalin

1 reference

12 December 2020

Evidence for the Role of Megalin in Renal Uptake of Transthyretin

1 reference

12 December 2020

Uptake of circulating insulin-like growth factors (IGFs) into cerebrospinal fluid appears to be independent of the IGF receptors as well as IGF-binding proteins.

1 reference

12 December 2020

An endocytosis defect as a possible cause of proteinuria in polycystic kidney disease

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12 December 2020

Circulating insulin-like growth factor I mediates exercise-induced increases in the number of new neurons in the adult hippocampus.

1 reference

12 December 2020

Insulin-like growth factor I (IGF-I) protects cells from apoptosis by Alzheimer's V642I mutant amyloid precursor protein through IGF-I receptor in an IGF-binding protein-sensitive manner.

1 reference

12 December 2020

Serum growth factors and neuroprotective surveillance: focus on IGF-1.

1 reference

12 December 2020

Cubilin and megalin: partners in lipoprotein and vitamin metabolism

1 reference

12 December 2020

Circulating insulin-like growth factor I mediates the protective effects of physical exercise against brain insults of different etiology and anatomy.

1 reference

12 December 2020

Dual roles for the Dab2 adaptor protein in embryonic development and kidney transport

1 reference

12 December 2020

Megalin and cubilin: multifunctional endocytic receptors

1 reference

12 December 2020

Serum insulin-like growth factor I regulates brain amyloid-beta levels

1 reference

12 December 2020

Insulin-like growth factor-1 promotes neuronal glucose utilization during brain development and repair processes

1 reference

12 December 2020

Sedentary life impairs self-reparative processes in the brain: the role of serum insulin-like growth factor-I.

1 reference

12 December 2020

The evolution of transthyretin synthesis in the choroid plexus

1 reference

12 December 2020

Insulin-like growth factor I modifies electrophysiological properties of rat brain stem neurons

1 reference

12 December 2020

Selective interaction of megalin with postsynaptic density-95 (PSD-95)-like membrane-associated guanylate kinase (MAGUK) proteins

1 reference

12 December 2020

Spherical aggregates of beta-amyloid (amylospheroid) show high neurotoxicity and activate tau protein kinase I/glycogen synthase kinase-3beta

1 reference

12 December 2020

Insulin receptor substrate-2 deficiency impairs brain growth and promotes tau phosphorylation

1 reference

12 December 2020

Glycogen synthase kinase-3 induces Alzheimer's disease-like phosphorylation of tau: generation of paired helical filament epitopes and neuronal localisation of the kinase

1 reference

12 December 2020

Increased soluble amyloid-beta peptide and memory deficits in amyloid model mice overexpressing the low-density lipoprotein receptor-related protein

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12 December 2020

Role for neuronal insulin resistance in neurodegenerative diseases

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12 December 2020

Role of tau protein in both physiological and pathological conditions.

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12 December 2020

Insulin-like growth factor-I, cognition and brain aging

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12 December 2020

Gene therapy of the brain: the trans-vascular approach

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12 December 2020

Clearing amyloid through the blood-brain barrier

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12 December 2020

Insulin-like growth factor I is required for vessel remodeling in the adult brain

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12 December 2020

LRP/amyloid beta-peptide interaction mediates differential brain efflux of Abeta isoforms.

1 reference

12 December 2020

Natural oligomers of the amyloid-beta protein specifically disrupt cognitive function

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12 December 2020

Twenty years of the Alzheimer's disease amyloid hypothesis: a genetic perspective

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12 December 2020

Environmental enrichment reduces Abeta levels and amyloid deposition in transgenic mice

1 reference

12 December 2020

Voluntary exercise decreases amyloid load in a transgenic model of Alzheimer's disease.

1 reference

12 December 2020

Therapeutic actions of insulin-like growth factor I on APP/PS2 mice with severe brain amyloidosis.

1 reference

12 December 2020

Blockade of the insulin-like growth factor I receptor in the choroid plexus originates Alzheimer's-like neuropathology in rodents: new cues into the human disease?

1 reference

12 December 2020

Behind the AIDS mailer

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12 December 2020

Developments of a water-maze procedure for studying spatial learning in the rat

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12 December 2020

Localization of insulin-like growth factor binding protein-2 messenger RNA during postnatal brain development: correlation with insulin-like growth factors I and II.

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12 December 2020

Transthyretin sequesters amyloid beta protein and prevents amyloid formation

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12 December 2020

An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants.

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12 December 2020

Patterns of insulin-like growth factor and IGF receptor gene expression in the brain. Functional implications

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12 December 2020

Signal transducing molecules and glycosyl-phosphatidylinositol-linked proteins form a caveolin-rich insoluble complex in MDCK cells

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12 December 2020

Glycoprotein 330/megalin: probable role in receptor-mediated transport of apolipoprotein J alone and in a complex with Alzheimer disease amyloid beta at the blood-brain and blood-cerebrospinal fluid barriers

1 reference

12 December 2020

Amyloid beta-peptide is transported on lipoproteins and albumin in human plasma

1 reference

12 December 2020

Interaction of apolipoprotein J-amyloid beta-peptide complex with low density lipoprotein receptor-related protein-2/megalin. A mechanism to prevent pathological accumulation of amyloid beta-peptide

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12 December 2020

Insulin and insulin-like growth factor-1 regulate tau phosphorylation in cultured human neurons.

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12 December 2020

Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo

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12 December 2020

Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins

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12 December 2020

A third-generation lentivirus vector with a conditional packaging system

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12 December 2020

Megalin is an endocytic receptor for insulin

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12 December 2020

10.1523/JNEUROSCI.2909-05.2005

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16306401%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16306401%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

PubMed publication ID

16306401

1 reference