Insight into the recognition patterns of the ErbB receptor family transmembrane domains: heterodimerization models through molecular dynamics search (Q80951655)

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scientific article published on 26 March 2008

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English	Insight into the recognition patterns of the ErbB receptor family transmembrane domains: heterodimerization models through molecular dynamics search	scientific article published on 26 March 2008

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18365190%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

Insight into the recognition patterns of the ErbB receptor family transmembrane domains: heterodimerization models through molecular dynamics search (English)

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18365190%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

protein heterodimerization activity

1 reference

based on heuristic

inferred from title

Norbert Garnier

2

1 reference

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4 January 2020

author name string

Oumarou Samna Soumana

1

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4 January 2020

Monique Genest

3

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4 January 2020

publication date

26 March 2008

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4 January 2020

European Biophysics Journal

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Europe PubMed Central

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4 January 2020

37

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4 January 2020

6

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4 January 2020

851-864

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18365190%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

Hydrophobic mismatch between helices and lipid bilayers.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Statistical analysis of amino acid patterns in transmembrane helices: the GxxxG motif occurs frequently and in association with beta-branched residues at neighboring positions.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A basic peptide within the juxtamembrane region is required for EGF receptor dimerization

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

How proteins adapt to a membrane-water interface

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell signaling by receptor tyrosine kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transmembrane helices of membrane proteins may flex to satisfy hydrophobic mismatch.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular dynamics simulation approach for the prediction of transmembrane helix-helix heterodimers assembly

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Study of the insulin dimerization: binding free energy calculations and per-residue free energy decomposition

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The cellular response to neuregulins is governed by complex interactions of the erbB receptor family

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

erbB-2 is a potent oncogene when overexpressed in NIH/3T3 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of helix interactions in membrane and soluble alpha-bundle proteins.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The type 1 (EGFR-related) family of growth factor receptors and their ligands

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The extracellular region of ErbB4 adopts a tethered conformation in the absence of ligand

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

EGF-ERBB signalling: towards the systems level

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of glycophorin A transmembrane helix interactions by lipid bilayers: molecular dynamics calculations.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An open-and-shut case? Recent insights into the activation of EGF/ErbB receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sequence context strongly modulates association of polar residues in transmembrane helices

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Helix packing in membrane proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Electrostatic interactions of peptides flanking the tyrosine kinase domain in the epidermal growth factor receptor provides a model for intracellular dimerization and autophosphorylation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The ErbB signaling network: receptor heterodimerization in development and cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modeling the effects of HER/ErbB1-3 coexpression on receptor dimerization and biological response

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polar residues drive association of polyleucine transmembrane helices

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specificity in transmembrane helix-helix interactions mediated by aromatic residues.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Helix to helix packing in proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A transmembrane helix dimer: structure and implications

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aromatic and cation-pi interactions enhance helix-helix association in a membrane environment

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Similarity of protein encoded by the human c-erb-B-2 gene to epidermal growth factor receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Helix-packing motifs in membrane proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A dimerization hierarchy in the transmembrane domains of the HER receptor family

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Single-molecule imaging of EGFR signalling on the surface of living cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

How protein transmembrane segments sense the lipid environment

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Crystal structure of the complex of human epidermal growth factor and receptor extracellular domains

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The crystal structure of a truncated ErbB2 ectodomain reveals an active conformation, poised to interact with other ErbB receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A Putative Mechanism for Downregulation of the Catalytic Activity of the EGF Receptor via Direct Contact between Its Kinase and C-Terminal Domains

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Type 1 growth factor receptors and their ligands considered as a complex system

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two motifs within a transmembrane domain, one for homodimerization and the other for heterodimerization

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The single transmembrane domains of ErbB receptors self-associate in cell membranes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The tethered configuration of the EGF receptor extracellular domain exerts only a limited control of receptor function

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oncogenic activation of the neu-encoded receptor protein by point mutation and deletion

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure of the extracellular region of HER3 reveals an interdomain tether

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dimerization of the extracellular domain of the receptor for epidermal growth factor containing the membrane-spanning segment in response to treatment with epidermal growth factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of c-erbB-3 binding sites for phosphatidylinositol 3'-kinase and SHC using an EGF receptor/c-erbB-3 chimera

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Signaling through ERBB receptors: multiple layers of diversity and control

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ligand-specific activation of HER4/p180erbB4, a fourth member of the epidermal growth factor receptor family

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Untangling the ErbB signalling network

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A hierarchical network of interreceptor interactions determines signal transduction by Neu differentiation factor/neuregulin and epidermal growth factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ErbB-2 is a common auxiliary subunit of NDF and EGF receptors: implications for breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutational activation of ErbB family receptor tyrosine kinases: insights into mechanisms of signal transduction and tumorigenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Crystal structure of a truncated epidermal growth factor receptor extracellular domain bound to transforming growth factor alpha

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GXXXG and AXXXA: common alpha-helical interaction motifs in proteins, particularly in extremophiles

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two EGF molecules contribute additively to stabilization of the EGFR dimer

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An allosteric mechanism for activation of the kinase domain of epidermal growth factor receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of receptor tyrosine kinase transmembrane domains in cell signaling and human pathologies

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation and characterization of ERBB3, a third member of the ERBB/epidermal growth factor receptor family: evidence for overexpression in a subset of human mammary tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantification of helix-helix binding affinities in micelles and lipid bilayers

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ligand-induced structural transitions in ErbB receptor extracellular domains

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transmembrane helix-helix interactions: comparative simulations of the glycophorin a dimer

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Helix packing in polytopic membrane proteins: role of glycine in transmembrane helix association

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of preformed EGF receptor dimers by ligand-induced rotation of the transmembrane domain

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The neu oncogene encodes an epidermal growth factor receptor-related protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effective energy function for proteins in lipid membranes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ErbB receptors: new insights on mechanisms and biology

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bivalence of EGF-like ligands drives the ErbB signaling network

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Motifs of serine and threonine can drive association of transmembrane helices

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Helix-helix packing and interfacial pairwise interactions of residues in membrane proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The transmembrane domains of ErbB receptors do not dimerize strongly in micelles

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A putative molecular-activation switch in the transmembrane domain of erbB2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polar side chains drive the association of model transmembrane peptides

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidermal growth factor-related peptides and their receptors in human malignancies

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

EGF activates its receptor by removing interactions that autoinhibit ectodomain dimerization

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidermal growth factor receptor dimerization and activation require ligand-induced conformational changes in the dimer interface

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased tyrosine kinase activity associated with the protein encoded by the activated neu oncogene

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular modeling of nearly full-length ErbB2 receptor.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Internal packing of helical membrane proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rotational coupling of the transmembrane and kinase domains of the Neu receptor tyrosine kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogene

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A sequence motif in the transmembrane region of growth factor receptors with tyrosine kinase activity mediates dimerization

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18365190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00249-008-0293-0

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18365190%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18365190%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

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