Mutation of SHOC2 promotes aberrant protein N-myristoylation and causes Noonan-like syndrome with loose anagen hair (Q24336157)

positive regulation of Ras protein signal transduction

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Bruno Dallapiccola

27

0 references

Giuseppe Zampino

12

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Wendy Schackwitz

10

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Anna Sarkozy

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Viviana Cordeddu

1

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Kerstin Kutsche

19

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Marco Tartaglia

31

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Francesca Lepri

17

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Elisabetta Flex

16

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Laura Mazzanti

13

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Elia Di Schiavi

Elia Di Schiavi

2

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Avi Ma'ayan

Avi Ma'ayan

4

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0 references

25

Martin Zenker

0 references

Anna Lipzen

11

Anna Lipzen

0 references

Len A. Pennacchio

3

Len A Pennacchio

0 references

Valentina Fodale

6

Valentina Fodale

0 references

author name string

Alessio Cardinale

8

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Joel Martin

9

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Maria C Digilio

14

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Simone Martinelli

15

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Deborah Bartholdi

18

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Giovanni B Ferrero

20

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Cecilia Anichini

21

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Angelo Selicorni

22

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Cesare Rossi

23

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Romano Tenconi

24

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Daniela Merlo

26

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Ravi Iyengar

28

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Paolo Bazzicalupo

29

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Bruce D Gelb

MINT: the Molecular INTeraction database

30

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language of work or name

English

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publication date

September 2009

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published in

Nature Genetics

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volume

41

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issue

9

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page(s)

1022-6

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cites work

1 reference

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A phosphatase holoenzyme comprised of Shoc2/Sur8 and the catalytic subunit of PP1 functions as an M-Ras effector to modulate Raf activity

19 March 2017

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The leucine-rich repeat protein SUR-8 enhances MAP kinase activation and forms a complex with Ras and Raf

19 March 2017

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SUR-8, a conserved Ras-binding protein with leucine-rich repeats, positively regulates Ras-mediated signaling in C. elegans

19 March 2017

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soc-2 encodes a leucine-rich repeat protein implicated in fibroblast growth factor receptor signaling

19 March 2017

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The biology and enzymology of protein N-myristoylation

19 March 2017

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19 March 2017

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Mouse model of Noonan syndrome reveals cell type- and gene dosage-dependent effects of Ptpn11 mutation

19 March 2017

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A note on two problems in connexion with graphs

19 March 2017

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Multiple lentigines syndrome

22 April 2017

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Hyperactive Ras in developmental disorders and cancer

22 April 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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Loose anagen hair in a child with Noonan's syndrome

27 September 2017

1 reference

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Noonan-like syndrome with loose anagen hair: a new syndrome?

30 May 2018

1 reference

Somatic mutations in PTPN11 in juvenile myelomonocytic leukemia, myelodysplastic syndromes and acute myeloid leukemia

21 January 2018

1 reference

Mutations in PTPN11 implicate the SHP-2 phosphatase in leukemogenesis

21 January 2018

1 reference

ced-10 Rac and mig-2 function redundantly and act with unc-73 trio to control the orientation of vulval cell divisions and migrations in Caenorhabditis elegans

21 January 2018

1 reference

Gain-of-function SOS1 mutations cause a distinctive form of Noonan syndrome.

21 January 2018

1 reference

Amino acid residue penultimate to the amino-terminal gly residue strongly affects two cotranslational protein modifications, N-myristoylation and N-acetylation

21 January 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/19684605

21 January 2018

1 reference

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

GTPase and adenylate cyclase desensitize at different rates in NG108-15 cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19684605

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Clinical and molecular studies in a large Dutch family with Noonan syndrome

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19684605

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NG.425

1 reference

Dimensions Publication ID

725412

1036833666

0 references

725412

1 reference

1 reference

1 reference