Histone deacetylase 8 safeguards the human ever-shorter telomeres 1B (hEST1B) protein from ubiquitin-mediated degradation (Q24671304)

Heat shock protein 90 alpha family class A member 1

1 reference

Heat shock protein 90 alpha family class B member 1

1 reference

Histone deacetylase 8

1 reference

Heat shock protein family A (Hsp70) member 1A

1 reference

SMG5 nonsense mediated mRNA decay factor

1 reference

STIP1 homology and U-box containing protein 1

1 reference

histone deacetylase binding

1 reference

author name string

Heehyoung Lee

1

0 references

Nilanjan Sengupta

2

0 references

Alejandro Villagra

3

0 references

Natalie Rezai-Zadeh

4

0 references

Edward Seto

Molecular and Cellular Biology

5

0 references

language of work or name

English

0 references

publication date

July 2006

0 references

published in

0 references

volume

26

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issue

14

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page(s)

5259-69

0 references

cites work

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Characterization of human Smg5/7a: a protein with similarities to Caenorhabditis elegans SMG5 and SMG7 that functions in the dephosphorylation of Upf1.

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The inv(16) fusion protein associates with corepressors via a smooth muscle myosin heavy-chain domain

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MDM2-HDAC1-mediated deacetylation of p53 is required for its degradation

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CHIP is associated with Parkin, a gene responsible for familial Parkinson's disease, and enhances its ubiquitin ligase activity

7 April 2017

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Cloning and functional characterization of HDAC11, a novel member of the human histone deacetylase family

7 April 2017

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Identification of components of the murine histone deacetylase 6 complex: link between acetylation and ubiquitination signaling pathways

7 April 2017

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hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase

7 April 2017

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Negative control of p53 by Sir2alpha promotes cell survival under stress

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Telomerase and breast cancer

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The co-chaperone CHIP regulates protein triage decisions mediated by heat-shock proteins

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Cloning and characterization of a novel human histone deacetylase, HDAC8

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A bacterial two-hybrid selection system for studying protein-DNA and protein-protein interactions

7 April 2017

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Cloning and characterization of a novel human class I histone deacetylase that functions as a transcription repressor

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Resistance to apoptosis in human cells conferred by telomerase function and telomere stability

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Identification of CHIP, a novel tetratricopeptide repeat-containing protein that interacts with heat shock proteins and negatively regulates chaperone functions

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Functional requirement of p23 and Hsp90 in telomerase complexes

7 April 2017

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A human homolog of yeast Est1 associates with telomerase and uncaps chromosome ends when overexpressed

7 April 2017

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TRF1 is degraded by ubiquitin-mediated proteolysis after release from telomeres

7 April 2017

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CHIP-mediated stress recovery by sequential ubiquitination of substrates and Hsp70

7 April 2017

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Sp1 and Sp3 recruit histone deacetylase to repress transcription of human telomerase reverse transcriptase (hTERT) promoter in normal human somatic cells

7 April 2017

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Human class I histone deacetylase complexes show enhanced catalytic activity in the presence of ATP and co-immunoprecipitate with the ATP-dependent chaperone protein Hsp70

7 April 2017

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CHIP is a U-box-dependent E3 ubiquitin ligase: identification of Hsc70 as a target for ubiquitylation

7 April 2017

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Deacetylation of p53 modulates its effect on cell growth and apoptosis

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Role of the histone deacetylase complex in acute promyelocytic leukaemia

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Conditional telomerase induction causes proliferation of hair follicle stem cells

7 April 2017

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The Hsc70 co-chaperone CHIP targets immature CFTR for proteasomal degradation

7 April 2017

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Histone deacetylase HDAC8 associates with smooth muscle alpha-actin and is essential for smooth muscle cell contractility.

7 April 2017

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Alternative effects of the ubiquitin-proteasome pathway on glucocorticoid receptor down-regulation and transactivation are mediated by CHIP, an E3 ligase.

28 September 2017

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Notch-induced E2A degradation requires CHIP and Hsc70 as novel facilitators of ubiquitination

28 September 2017

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Beginning to understand the end of the chromosome

28 September 2017

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Telomerase: what are the Est proteins doing?

28 September 2017

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Chaperone-dependent E3 ubiquitin ligase CHIP mediates a degradative pathway for c-ErbB2/Neu

28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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Telomerase regulation: not just flipping the switch

28 September 2017

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Telomerase activation by histone deacetylase inhibitor in normal cells

28 September 2017

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Stable association of hsp90 and p23, but Not hsp70, with active human telomerase

28 September 2017

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Histone deacetylation is involved in the transcriptional repression of hTERT in normal human cells

28 September 2017

1 reference

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Cloning and characterization of human histone deacetylase 8.

28 September 2017

1 reference

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The catalytic subunit of telomerase protects neurons against amyloid beta-peptide-induced apoptosis

28 September 2017

1 reference

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Transcriptional repression by wild-type p53 utilizes histone deacetylases, mediated by interaction with mSin3a.

28 September 2017

1 reference

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Chromosome healing in mouse embryonic stem cells

28 September 2017

1 reference

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The assembly of progesterone receptor-hsp90 complexes using purified proteins

28 September 2017

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CHIP is a chaperone-dependent E3 ligase that ubiquitylates unfolded protein

28 September 2017

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Structural snapshots of human HDAC8 provide insights into the class I histone deacetylases

30 May 2018

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Molecular evolution of the histone deacetylase family: functional implications of phylogenetic analysis.

28 November 2018

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Epigenetic regulation of telomere length in mammalian cells by the Suv39h1 and Suv39h2 histone methyltransferases.

28 November 2018

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The histone deacetylase inhibitor trichostatin A derepresses the telomerase reverse transcriptase (hTERT) gene in human cells

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592721

UbcD1, a Drosophila ubiquitin-conjugating enzyme required for proper telomere behavior

28 November 2018

1 reference

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Reconstitution of the steroid receptor.hsp90 heterocomplex assembly system of rabbit reticulocyte lysate.

28 November 2018

1 reference

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Est1p as a cell cycle-regulated activator of telomere-bound telomerase

28 November 2018

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12 December 2020

Interactions of p60, a mediator of progesterone receptor assembly, with heat shock proteins hsp90 and hsp70

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12 December 2020

Chromosome healing of constitutional chromosome deletions studied by microdissection

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12 December 2020

Anti-apoptotic role of telomerase in pheochromocytoma cells

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12 December 2020

Use of Histone Deacetylase 8 (HDAC8), a New Marker of Smooth Muscle Differentiation, in the Classification of Mesenchymal Tumors of the Uterus

1 reference

12 December 2020