Development of autophagy inducers in clinical medicine (Q26822948)

Crossref

language of work or name

1 reference

January 2015

1 reference

Journal of Clinical Investigation

published in

1 reference

volume

125

1 reference

page(s)

14-24

1 reference

issue

1

1 reference

EGFR-mediated Beclin 1 phosphorylation in autophagy suppression, tumor progression, and tumor chemoresistance

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Vitamin D inhibits human immunodeficiency virus type 1 and Mycobacterium tuberculosis infection in macrophages through the induction of autophagy

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Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease

7 April 2017

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Identification of a candidate therapeutic autophagy-inducing peptide

7 April 2017

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The role of Atg proteins in autophagosome formation

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Autophagy-dependent anticancer immune responses induced by chemotherapeutic agents in mice

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TFEB links autophagy to lysosomal biogenesis

7 April 2017

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A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells

7 April 2017

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Pharmacologic agents targeting autophagy

28 September 2017

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Caffeine prevents human prion protein-mediated neurotoxicity through the induction of autophagy

28 September 2017

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Genetic and chemical correction of cholesterol accumulation and impaired autophagy in hepatic and neural cells derived from Niemann-Pick Type C patient-specific iPS cells.

28 September 2017

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Autophagy and human disease: emerging themes

28 September 2017

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28 September 2017

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Autophagy is critical for pancreatic tumor growth and progression in tumors with p53 alterations

28 September 2017

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Atg16L1 T300A variant decreases selective autophagy resulting in altered cytokine signaling and decreased antibacterial defense

28 September 2017

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Glucose starvation inhibits autophagy via vacuolar hydrolysis and induces plasma membrane internalization by down-regulating recycling.

28 September 2017

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Essential role for autophagy in the maintenance of immunological memory against influenza infection

28 September 2017

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Epidermal growth factor receptor inhibition slows progression of diabetic nephropathy in association with a decrease in endoplasmic reticulum stress and an increase in autophagy

28 September 2017

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Autophagy--a key player in cellular and body metabolism

28 September 2017

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The impact of autophagy on cell death modalities.

28 September 2017

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A Crohn's disease variant in Atg16l1 enhances its degradation by caspase 3.

28 September 2017

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Nilotinib-induced autophagic changes increase endogenous parkin level and ubiquitination, leading to amyloid clearance

28 September 2017

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Autophagy and human diseases

28 September 2017

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p53 status determines the role of autophagy in pancreatic tumour development

28 September 2017

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Impaired autophagy in the lipid-storage disorder Niemann-Pick type C1 disease

28 September 2017

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Autosis is a Na+,K+-ATPase-regulated form of cell death triggered by autophagy-inducing peptides, starvation, and hypoxia-ischemia

28 September 2017

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Exploiting the bad eating habits of Ras-driven cancers

28 September 2017

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Regulation of autophagy by mTOR-dependent and mTOR-independent pathways: autophagy dysfunction in neurodegenerative diseases and therapeutic application of autophagy enhancers.

28 September 2017

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Chemical screening platforms for autophagy drug discovery to identify therapeutic candidates for Huntington's disease and other neurodegenerative disorders.

28 September 2017

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Autophagy inhibition radiosensitizes in vitro, yet reduces radioresponses in vivo due to deficient immunogenic signalling

28 September 2017

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Therapeutic targeting of autophagy in disease: biology and pharmacology

28 September 2017

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Caffeine stimulates hepatic lipid metabolism by the autophagy-lysosomal pathway in mice.

28 September 2017

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Autophagy suppresses progression of K-ras-induced lung tumors to oncocytomas and maintains lipid homeostasis

28 September 2017

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Emerging regulation and functions of autophagy

28 September 2017

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28 September 2017

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28 September 2017

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miR-30a downregulation aggravates pressure overload-induced cardiomyocyte hypertrophy

28 September 2017

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Diminished autophagy limits cardiac injury in mouse models of type 1 diabetes

28 September 2017

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Signals from the lysosome: a control centre for cellular clearance and energy metabolism

28 September 2017

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Transcription factor EB (TFEB) is a new therapeutic target for Pompe disease

28 September 2017

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The regulatory role of NF-κB in autophagy-like cell death after focal cerebral ischemia in mice

28 September 2017

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Ubiquitin-independent function of optineurin in autophagic clearance of protein aggregates

28 September 2017

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Epidermal growth factor receptor is a preferred target for treating amyloid-β-induced memory loss

28 September 2017

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Ubiquitination and selective autophagy

28 September 2017

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Inhibition of autophagy ameliorates acute lung injury caused by avian influenza A H5N1 infection.

28 September 2017

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Autophagy required for hepatitis B virus replication in transgenic mice

28 September 2017

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Concurrent detection of autolysosome formation and lysosomal degradation by flow cytometry in a high-content screen for inducers of autophagy

28 September 2017

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Sorafenib enhances pemetrexed cytotoxicity through an autophagy-dependent mechanism in cancer cells

28 September 2017

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Hormonally active vitamin D3 (1alpha,25-dihydroxycholecalciferol) triggers autophagy in human macrophages that inhibits HIV-1 infection

28 September 2017

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Oncogenic Ras-induced expression of Noxa and Beclin-1 promotes autophagic cell death and limits clonogenic survival

28 September 2017

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Autophagosomes and human diseases

28 September 2017

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Autophagy protein microtubule-associated protein 1 light chain-3B (LC3B) activates extrinsic apoptosis during cigarette smoke-induced emphysema

28 September 2017

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An autophagy-enhancing drug promotes degradation of mutant alpha1-antitrypsin Z and reduces hepatic fibrosis.

28 September 2017

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Targeting the prodeath and prosurvival functions of autophagy as novel therapeutic strategies in cancer

28 September 2017

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Rilmenidine attenuates toxicity of polyglutamine expansions in a mouse model of Huntington's disease

28 September 2017

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In vivo requirement for Atg5 in antigen presentation by dendritic cells

28 September 2017

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Autophagy regulates pancreatic beta cell death in response to Pdx1 deficiency and nutrient deprivation

28 September 2017

1 reference

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The role of exercise and PGC1alpha in inflammation and chronic disease

28 September 2017

1 reference

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Bcl-2 family members: dual regulators of apoptosis and autophagy

28 September 2017

1 reference

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Inhibition of autophagy prevents hippocampal pyramidal neuron death after hypoxic-ischemic injury

28 September 2017

1 reference

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Small molecule regulators of autophagy identified by an image-based high-throughput screen

28 September 2017

1 reference

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Alternate-day fasting and chronic disease prevention: a review of human and animal trials

28 September 2017

1 reference

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Cardiac autophagy is a maladaptive response to hemodynamic stress

28 September 2017

1 reference

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Small molecules enhance autophagy and reduce toxicity in Huntington's disease models.

28 September 2017

1 reference

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Dynein mutations impair autophagic clearance of aggregate-prone proteins

28 September 2017

1 reference

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Autophagy in metazoans: cell survival in the land of plenty

28 September 2017

1 reference

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Vitamin D analog EB1089 triggers dramatic lysosomal changes and Beclin 1-mediated autophagic cell death.

28 September 2017

1 reference

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Restriction of food intake prevents postinfarction heart failure by enhancing autophagy in the surviving cardiomyocytes

28 September 2017

1 reference

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Glucose-starved cells do not engage in prosurvival autophagy

31 May 2018

1 reference

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Atg16l1 is required for autophagy in intestinal epithelial cells and protection of mice from Salmonella infection

31 May 2018

1 reference

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Overexpression of beclin1 induced autophagy and apoptosis in lungs of K-rasLA1 mice

31 May 2018

1 reference

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Tyrosine kinase inhibition increases functional parkin-Beclin-1 interaction and enhances amyloid clearance and cognitive performance

31 May 2018

1 reference

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Proteomic mapping of mitochondria in living cells via spatially restricted enzymatic tagging.

31 May 2018

1 reference

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Pancreatic acinar cell-specific autophagy disruption reduces coxsackievirus replication and pathogenesis in vivo

31 May 2018

1 reference

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Insufficient activation of autophagy allows cellular damage to accumulate in critically ill patients

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382267

Differential involvement of Atg16L1 in Crohn disease and canonical autophagy: analysis of the organization of the Atg16L1 complex in fibroblasts

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382267

Effect of tolerating macronutrient deficit on the development of intensive-care unit acquired weakness: a subanalysis of the EPaNIC trial.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382267

A dual role for autophagy in a murine model of lung cancer

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382267

Statin therapy reduces the mycobacterium tuberculosis burden in human macrophages and in mice by enhancing autophagy and phagosome maturation.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382267

The involvement of autophagy pathway in exaggerated ischemic brain damage in diabetic mice

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382267

Autophagy is involved in traumatic brain injury-induced cell death and contributes to functional outcome deficits in mice

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382267

Autophagy is required for dietary restriction-mediated life span extension in C. elegans

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382267

Distinct roles of autophagy in the heart during ischemia and reperfusion: roles of AMP-activated protein kinase and Beclin 1 in mediating autophagy.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382267

Autophagy as a basis for the health-promoting effects of vitamin D

28 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/25654546